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Biologic Markers in Reproductive Toxicology (1989)
Commission on Life Sciences (CLS)

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. "III. Biologic Markers of Toxicity during Pregnancy." Biologic Markers in Reproductive Toxicology. Washington, DC: The National Academies Press, 1989.

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Page
203
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Page
203
Front Matter (R1-R24)
Executive Summary (1-14)
1. Report of the Oversight Committee (15-36)
I. Biologic Markers in Male Reproductive and Gametic Genetic Toxicology (37-38)
2. Introduction (39-42)
3. Clinical Evaluation of Male Infertility (43-46)
4. Biologic Markers of Testicular Function (47-62)
5. Biologic Markers of Epididymal Structure and Function (63-76)
6. Biologic Markers of Accessory Sex Organ Structure and Function (77-82)
7. Biologic Markers of Human Male Reproductive Health and Physiologic Damage (83-106)
8. Assessing Transmitted Mutations in Mice (107-118)
9. Markers for Measuring Germinal Genetic Toxicity and Heritable Mutations in People (119-140)
10. Conclusions and Recommendations (141-146)
II. Biologic Markers in Female Reproductive Toxicology (147-148)
11. Introduction (149-162)
12. Biologic Markers of Genetic Damage in Females (163-168)
13. Biologic Markers of Reproductive Development and Aging (169-178)
14. Biologic Markers of Nonconceptive Menstrual Cycles (179-186)
15. Developing Assays of Biologic Markers for Epidemiologic Studies: Experience with a Marker of Pregnancy and Early Loss (187-196)
16. Conclusions and Recommendations (197-202)
III. Biologic Markers of Toxicity during Pregnancy (203-204)
17. Introduction (205-210)
18. Molecular Biology: Developing DNA Markers of Genotoxic Effects (211-214)
19. Reproductive Immunology: Biologic Markers of Compromised Pregnancies (215-222)
20. Cell Biology: Identifying Biologic Markers Expressed during Early Pregnancy (223-240)
21. Physiologic Assessment of Fetal Compromise (241-246)
22. Biologic Markers of Exposure during Pregnancy: Pharmacokinetic Assessments (247-252)
23. Conclusions and Recommendations (253-262)
IV. Biologic Markers in Neurodevelopmental Toxicology (263-264)
24. Introduction (265-272)
25. Developmental Neurobiology of the Central Nervous System (273-280)
26. Morphologic, Neurochemical, and Behavioral Responses to Toxic Agents (281-288)
27. Methodologic Issues of Extrapolation from Animal Studies to Human Toxicant Exposure (289-296)
28. Lead as a Paradigm for the Study of Neurodevelopmental Toxicology (297-302)
29. Conclusions and Recommendations (303-310)
Appendix: Assessing the Validity of Biologic Markers: Alpha-Fetoprotein (311-318)
References (319-372)
Biographies (373-380)
Index (381-396)

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biologic markers