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The Outiook for
Science and
Technology
1 985
Committee on Science,
Engineering, and Public Policy
NATIONAL ACADEMY OF SCIENCES
NATIONAL ACADEMY OF ENGINEERING
INSTITUTE OF MEDICINE
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NOTICE: The National Academy of Sciences was established in 1863 by Act of Congress as a
private, nonprofit, self-governing membership corporation for the furtherance of science and
technology for the general welfare. The terms of its charter require the National Academy of
Sciences to advise the federal government upon request within its fields of competence.
Under this corporate charter, the National Academy of Engineering and the Institute of
Medicine were established in 1964 and 1970, respectively.
The Committee on Science, Engineering, and Public Policy is a joint committee of the
National Academy of Sciences, the National Academy of Engineering, and the Institute of
Medicine. It includes members of the councils of all three bodies.
This work was supported by the National Science Foundation under Grant PSP-
7913104.
Library of Congress Catalog Card Number 85~0421
Availablefor $3. 00 per copy (prepaid only)from
National Academy Press
2101 Constitution Ave., NW
Washington, DC 20418
Printed in the United States of America
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Preface
The 1985 Outlook for Science and Technology is the fourth
report in a series originally mandated by the National Science and
Technology Policy, Organization, and Priorities Act of 1976.
Subsequent to the passage of that Act, a reorganization of the
Executive Office of the President gave the National Science
Foundation responsibility for preparing the Outlooks. In turn,
the Foundation asked the National Academy of Sciences to assist.
Since 1982, the Outlooks have been prepared by the Committee
on Science, Engineering, and Public Policy (COSEPUP), ajoint
unit of the National Academy of Sciences, the National Acade-
my of Engineering, and the Institute of Medicine.
The purposes of these reports are to describe and discuss:
· current and emerging problems of national significance that
are identified through scientific research or in which scientific or
technical considerations are of major importance; and
· opportunities for the use of new and existing scientific and
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PREFACE
technological capabilities that can help to resolve these problems
and impediments to the effective use of these capabilities.
Issues presented in this Outlook were obtained from several
sources, including discussion within COSEPUP and from re-
search briefings prepared for the President's Office of Science
and Technology Policy (OSTP), the National Science Founda-
tion, and other federal agencies. These briefings summarized
research opportunities with the potential for high scientific re-
turns in a number of fields, identified by OSTP after consultation
with COSEPUP. Twenty-one briefings have been presented in
the last three years on subjects as diverse as agriculture, astron-
omy, atherosclerosis, catalysis and other topics in chemistry,
computer-aided manufacturing, information technology in pre-
college education, neuroscience, immunology, and cognitive
science and artificial intelligence.
In this report, we summarize the nine subjects that formed the
bases of the 1984 research briefings. Subjects of comparable
scientific merit could have been selected. However, as with past
briefings, the topics selected were those for which near-term
federal actions were considered likely.
Other suggestions for this Outlook came from the major units
of the National Research Council and from Councilors of the
National Academy of Sciences, the National Academy of Engi-
neering, and the Institute of Medicine.
The committee is grateful to all of these contributors and
especially to the members of its subcommittee responsible for
preparation of the 1985 Outlook: lacob Bigeleisen, of the State
University of New York at Stony Brook (chairman); Floyd E.
Bloom, of the Scripps Clinic and Research Foundation; Emilio
Q. Daddario, of Wilkes, Artis, Hedrick, and Inane; and Edward
A. Mason, of the Standard Oil Company (Indiana). The sub-
stantial contributions by Norman Metzger in preparing this
report are acknowledged.
LEON T. SILVER
Chairman
Committee on Science, Engineering,
and Public Policy
.
1V
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Committee on Science, Engineering,
and Public Policy
Subcommittee on the Outiook
for Science and Technology
JACOB BIGELEISEN, Leading Professor, Department of Chemistry,
State University of New York at Stony Brook (Chairman)
FLOYD E. BLOOM, Director and Member, Division of Preclinical
Neuroscience and Endocrinology, Scripps Clinic and
Research Foundation, La Jolla, California
EMILIO Q. DADDARIO, Wilkes, Artis, Hedrick, and Lane,
Attorneys at Law, Washington, D.C.
EDWARD A. MASON, Vice President, Research, Standard Oil
Company (Indiana), Naperville, Illinois
Staff
NORMAN METZGER, Staff Officer
AUDREY PENDERGAST, Associate Editor
GERRY KASARDA, Administrative Assistant
v
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Committee on Science' Engineering,
and Public Policy
LEON T. SILVER, William M. Keck Foundation Professor of
Geology, Division of Geological and Planetary Sciences,
California Institute of Technology, Pasadena, California
(:Chairman)
LINDA H. AIKEN,* Vice President for Research, The Robert Wood
Johnson Foundation, Princeton, New Jersey
RICHARD C. ATKINSON, Chancellor, University of California, San
Diego
JACOB BIGELEISEN, Leading Professor, Department of Chemistry,
State University of New York at Stony Brook
FLOYD E. BLOOM, Director and Member, Division of Preclinical
Neuroscience and Endocrinology, Scripps Clinic and
Research Foundation, La Jolla, California
~V. DALE COMPTON, Vice President, Research, Ford Motor
Company, Dearborn, Michigan
EMILIO Q. DADDARIO, Wilkes, Artis, Hedrick, and Lane,
Attorneys at Law, Washington, D.C.
GERALD P. DINNEEN, Vice President, Science and Technology,
Honeywell, Inc., Minneapolis, Minnesota
ALEXANDER FLAX, President Emeritus, Institute for Defense
Analyses, Alexandria, Virginia
ZVI GRILICHES, Professor, Department of Economics, Harvard
University, Cambridge, Massachusetts
PHILIP LEDER, TOhn Emory Andrus Professor and Chairman,
Department of Genetics, Harvard Medical School,
Cambridge, Massachusetts
GARDNER LINDZEY, President and Director, Center for Advanced
Study in the Behavioral Sciences, Palo Alto, California
*Term expired December 31, 1984.
V1
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COMMI T TEE
EDWARD A. MASON, Vice President, Research, Standard Oil
Company (Indiana), Naperville, Illinois
DANIEL NATHANS, Professor, Department of Molecular Biology
and Genetics, The Johns Hopkins University School of
Medicine, Baltimore, Maryland
GILBERT S. OMENN, Dean, School of Public Health and
Community Medicine, University of Washington, Seattle,
Washington
HERBERT A. SIMON, Richard King Mellon University Professor of
Computer Science and Psychology, Department of
Psychology, Carnegie-Mellon University, Pittsburgh,
Pennsylvania
F. KARL WILLENBROCK, Cecil H. Green Professor of Engineering,
School of Engineering and Applied Science, Southern
Methodist University, Dallas, Texas
Ex Officio Members
FRANK PRESS, President, National Academy of Sciences
ROBERT M. WHITE, President, National Academy of Engineering
FREDERICK C. ROBBINS, President, Institute of Medicine
COSEPUP Staff
ALLAN R. HOFFMAN, Executive Director
BARBARA A. CANDLAND, Administrative Assistant
JOANNA M. MASTANTUONO, Senior Secretary
vat
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Contents
OVERVIEW
I. RECENT PROGRESS IN SCIENCE AND
TECHNOLOGY . . .
Oncogenes ..............
Atherosclerosis......
Parasitism ..........
Chemical and Process Engineering
for Biotechnology.
Advanced Polymeric Composites
Supercomputer Architectures ....
Information Technology in Precollege
Education ....
Opportunities in Physics ........
Solar-Terrestrial Plasma Physics..
A- ~
... 10
11
12
... 13
14
· · -
1X
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CONTENTS
lI. AN OUTLINE OF SELECTED ISSUES.
International Competition in Science
and Technology.......................
~17
..... 18
Supercomputers, 18; Biochemical Engineering, 20;
Advanced Polymeric Composites, 22
Issues for the Congress, 22
Scientific and Engineering Personnel 23
Starting a Research Career, 23; Clinicians in
Research, 24; Possible Shortages, 24; Doctorates for
Non-U.S. Citizens, 25
Issues for the Congress, 27
Cooperative Work Across Disciplines. .
The Special Case of Agriculture, 29
Issues for the Congress, 30
Research and Transportation
Highways, 31
Issues for the Congress, 32
Facilities and Instrumentation
Large-Scale Facilities, 33; Medium-Scale
Instrumentation, 34; Planning New Facilities, 37
Issues for the Congress, 38
Issues in Genetic Engineering ~
28
30
33
40
Issues for the Congress, 41
Issues in Human Biology 4~1
In Vitro Fertilization and Implantation of Human
Eggs, 42; Genetic Therapy of Human Cells, 42
Issues for the Congress, 44
Scientific Communication, Technology Transfer,
and National Security 44
The Department of Defense, 45; The Department
of Commerce, 45
Issues for the Congress, 47
Global Atmospheric Effects of Nuclear
Explosions
Issues for the Congress, 49
Final Comment
x
... 48
... 49
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The OutlooFfor
Science and
Technology
1 985
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