Appendix

Workshop Agenda

INSTITUTE OF MEDICINE

National Academy of Sciences

Board on International Health

Board on Health Promotion and Disease Prevention

Workshop on Malaria Vaccines

19–20 October 1995

Cecil and Ida Green Building, Room 104

2001 Wisconsin Avenue, N.W.

Washington, DC 20007

(202) 334-3904

AGENDA

19 October 1995

8:30 a.m.–8:45 a.m.

Welcome and Introductions

 

Philip Russell, Chair, IOM Committee on Malaria Vaccines

8:45 a.m.–10:45 a.m.

SESSION I: SETTING THE STAGE

(8:45 a.m.–9:15 a.m.)

Malaria: The Deteriorating Situation

 

Donald Krogstad, Tulane University School of Public Health and Tropical Medicine, USA

(9:15 a.m.–9:45 a.m.)

The Promise of Malaria Vaccines

 

Jerald Sadoff, Merck Research Laboratories, USA



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Vaccines Against Malaria: Hope in a Gathering Storm Appendix Workshop Agenda INSTITUTE OF MEDICINE National Academy of Sciences Board on International Health Board on Health Promotion and Disease Prevention Workshop on Malaria Vaccines 19–20 October 1995 Cecil and Ida Green Building, Room 104 2001 Wisconsin Avenue, N.W. Washington, DC 20007 (202) 334-3904 AGENDA 19 October 1995 8:30 a.m.–8:45 a.m. Welcome and Introductions   Philip Russell, Chair, IOM Committee on Malaria Vaccines 8:45 a.m.–10:45 a.m. SESSION I: SETTING THE STAGE (8:45 a.m.–9:15 a.m.) Malaria: The Deteriorating Situation   Donald Krogstad, Tulane University School of Public Health and Tropical Medicine, USA (9:15 a.m.–9:45 a.m.) The Promise of Malaria Vaccines   Jerald Sadoff, Merck Research Laboratories, USA

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Vaccines Against Malaria: Hope in a Gathering Storm (9:45 a.m.–10:05 a.m.) Malaria Vaccines in the Field: A Perspective from the Africa Malaria Vaccine Testing Network   Wenceslaus Kilama, The African Malaria Vaccine Testing Network, Tanzania (10:05 a.m.–10:30 a.m.) Discussion   Moderator: Philip Russell 10:30 a.m.–11:00 a.m. Break 11:00 a.m.–12:00 p.m. SESSION II: MALARIA AS A PARADIGM   Stephen Hoffman, Naval Medical Research Institute, USA (11:40 a.m.–12:00 p.m.) Discussion   Moderator: Louis Miller, National Institutes of Health, USA 12:00 p.m.–1:00 p.m. Lunch 1:00 p.m.–3:30 p.m. SESSION III: CURRENT APPROACHES TO MALARIA VACCINE DEVELOPMENT (1:00 p.m.–1:25 p.m.) Preerythrocytic Vaccines   Ruth Nussenzweig, New York University Medical Center, USA (5 min.) Questions (1:30 p.m.–1:55 p.m.) Erythrocytic Vaccines   Graham Brown, The Walter and Eliza Hall Institute of Medical Research, Australia (5 min.) Questions (2:00 p.m.–2:25 p.m.) Transmission Blocking Vaccines   David Kaslow, National Institutes of Health, USA (5 min.) Questions (2:30 p.m.–3:30 p.m.) Discussion: Potential Immunologic Obstacles toDevelopment of an Optimal Multi-Immune Response, Multi-Stage Malaria Vaccine   Moderator: W. R. Ballou, Walter Reed Army Institute of Research, USA 3:30 p.m.–4:00 p.m. Break

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Vaccines Against Malaria: Hope in a Gathering Storm 4:00 p.m.–5:30 p.m. SESSION IV: ROUNDTABLE ON U.S. FEDERAL MALARIA VACCINE ACTIVITIES Summary of Agency Activities 20 October 1995 (4:00 p.m.–4:15 p.m.) Public Health Service   Daniel Colley, Centers for Disease Control and Prevention (4:15 p.m.–4:30 p.m.) Department of Defense   William Bancroft, U.S. Army Medical Research and Materiel Command (4:30 p.m.–4:45 p.m.) U.S. Agency for InternationalDevelopment   Carter Diggs, USAID (4:45 p.m.–5:00 p.m.) Federal Malaria Vaccine Coordinating Committee   Lee Hall, National Institutes of Health (5:00 p.m.–5:30 p.m.) Roundtable Discussion   Moderator: Lee Hall 5:30 p.m. Reception (North Prefunction Area, directly outside meeting room) 8:30 a.m.–10:15 a.m. SESSION V: ROUNDTABLE ON INDUSTRIAL SECTOR ACTIVITIES (8:30 a.m.–9:00 a.m.) Malaria Vaccine Development: A Perspective from Industry   Russell Howard, Glaxo-Wellcome (9:00 a.m.–9:35 a.m.) The following participants may wish to present for 5 min. each:   Ian Bathurst, LXR Biotechnology W. Neal Burnette, Molecular Pharmaceutics Corporation Kenneth Guito, Connaught Laboratories Maurice Hilleman, The Merck Institute Adeoye Olukotun, Bristol-Myers Squibb Company John Tine, Virogenetics Corporation

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Vaccines Against Malaria: Hope in a Gathering Storm (9:35 a.m.–10:15 a.m.) Roundtable Discussion Moderator: Russell Howard 10:15 a.m.–10:45 a.m. Break 10:45 a.m.–12:15 a.m. SESSION VI: ROUNDTABLE ON INTERNATIONAL COLLABORATION (10:45 a.m.–11:00 a.m.) Overview of Global Malaria Vaccine Activities Howard Engers, WHO Special Programme for Research and Training in Tropical Diseases, Switzerland (11:00 a.m.–11:15 a.m.) DANIDA and Commission of European Communities Palle Jakobsen, Denmark (11:15 a.m.–11:25 a.m.) African Malaria Vaccine Testing Network Wenceslaus Kilama, Tanzania (11:25 a.m.–11:35 a.m.) Walter and Eliza Hall Institute of Medical Research Graham Brown, Australia (11:35 a.m.–11:45 a.m.) Medical Research Council Michael Davies, Great Britain (11:45 a.m.–12:15 p.m.) Roundtable Discussion Moderator: Howard Engers (session will include participants from the Roundtable on U.S. Federal Malaria Vaccine Activities) 12:15 p.m.–1:00 p.m. SESSION VII: SUMMARY AND DISCUSSION OF FINDINGS, CONCLUSIONS, AND RECOMMENDATIONS Philip Russell, IOM Committee Chair 1:00 p.m. Workshop Adjournment 1:30 p.m.–5:00 p.m. EXECUTIVE SESSION Workshop Committee on Malaria Vaccines