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TABLE A.2 Potential Candidate Diseases for New or Improved Vaccine Development

Amebiasis

Ancylostomiasis (hookworm)

Ascariasis

Brucellosis

Chlamydial infections

Cholera

Dengue fever

Diarrheas

E. coli

Norwalk agent

Salmonella (nontyphoid)

Shigella

Rotavirus

Campylobacter

Filariasis

Giardiasis

Gonorrhea

Hantaan virus

Hemophilus influenzae type B

invasive disease

Hepatitis A

Hepatitis B

Influenza virus

Japanese encephalitis

Leishmaniasis

Leprosy

Malaria

Measles

Meningococcal meningitis

Onchocerciasis

Skin disease

River blindness

Pertussis

Rabies

Respiratory infections

Parainfluenza

Respiratory syncytial virus

Adenovirus

Streptococcus pneumoniae

Hemophilus influenzae

Schistosomiasis

Streptococcus group A

Streptococcus group B

Trichuriasis

Trypanosomiasis

African

South American

Tuberculosis

Typhoid

Yellow fever

TABLE A.3 Pathogens Not Included as Candidates but Discussed in the Committee’s First Report (Appendix B)

Acquired immune deficiency syndrome agent

Adenovirus (respiratory disease)

Anaerobic bacteria

Clostridium botulinum

Clostridium difficile

Clostridium perfringens

Clostridium tetani

Chlamydia

Epstein-Barr virus

Giardia lamblia

Hospital acquired infections (gram-negative bacteria)

Nontypable Hemophilus influenzae

Non-A, non-B hepatitis

Histoplasma capsulatum

Human papilloma virus

Kawasaki disease agent

Legionella spp. (Legionnaire’s disease)

Mycoplasma pneumoniae

Rhinovirus

Rickettsia rickettsii (Rocky Mountain spotted fever)

Salmonella spp. (nontyphoidal)

Staphylococcus aureus

Streptococcus mutans

Treponema pallidum (syphilis)

Treponema-like spirochete of Lyme disease



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