. "Appendix C: The Burden of Disease Resulting from Diarrhea." New Vaccine Development: Establishing Priorities: Volume II, Diseases of Importance in Developing Countries. Washington, DC: The National Academies Press, 1986.
The following HTML text is provided to enhance online
readability. Many aspects of typography translate only awkwardly to HTML.
Please use the page image
as the authoritative form to ensure accuracy.
New Vaccine Development: Establishing Priorities, Volume II, Diseases of Importance in Developing Countries
TABLE C.6 Distribution of Mild and Moderate Diarrheal Episodes by Etiology (percent)a
Age Group (years)
Pathogen
Under 2
2–4
Under 5
5–14
15–59
60 and Over
E. coli (enterotoxigenic)
25
20
22.5
25
20
20
Rotavirus
10
5
7
1
1
1
Salmonella
2
1
1
1
1
2
Shigella
5
10
8
10
10
15
aPercentages do not total 100 because some pathogens that cause diarrhea are not included due to poor vaccine prospects.
TABLE C.7 Distribution of Severe Diarrheal Episodes and Deaths by Etiology (percent)a
Age Group (years)
Pathogen
Under 2
2–4
Under 5
5–14
15–59
60 and Over
E. coli (enterotoxigenic)
20
20
20
20
20
20
Rotavirus
30
10
25
0
0
0
Salmonella
2
1
1
1
1
1
Shigella
10
20
15
20
20
25
aPercentages do not total 100 because some pathogens that cause diarrhea are not included due to poor vaccine prospects.
Combining estimates in Tables C.5, C.6, and C.7 yields (for enterotoxigenic E. coli, rotavirus, and shigella) distributions of illness burden shown in Tables C.8, C.9, and C.10, respectively. These estimates are used in the calculation of total disease burden values (see Chapter 4).
