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TABLE 2.2 A Hypothetical Example of Multiattribute Scoringa

 

Criterion (Weighting Factor)

 

Disease Impact (0.4)

Vaccine Costs and Efficacy (0.4)

Characteristics of Development (0.2)

 

Vaccine Candidate

Potential Lives Saved per Year (0.6)

Potential Direct Economic Cost Saved per Year (0.1)

Potential Morbidity Averted (0.3)

Subscore

Vaccine Efficacy (0.7)b

Ease of Implementation (0.2)

Cost of Production and Implementation (0.1)

Subscore

Cost of Development (0.2)

Time to Development (0.2)

Likelihood of Success (0.6)

Subscore

Total Score

A

67

33

60

61

75

100

50

77

80

60

80

76

70

B

100

100

30

79

60

60

50

59

40

100

65

67

68

C

20

67

10

22

50

60

0

47

0

60

50

42

36

D

0

33

100

33

40

30

100

44

100

20

90

78

46

aScores and subscores are normalized to 100.

bReduction in expected frequency of disease among vaccinees.



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