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Committee Biographies DANIEL B. MENZEL, Chairman, is professor of pharmacology and medicine at Duke University and director of chemical carcinogenesis and of environmental toxicology in the Duke Comprehensive Cancer Center. He has served as chairman of the Safe Drinking Water Committee of the NRC from 1981 to 1986, as chairman of the WHO working group on airborne carcinogens and other expert toxicology groups for the National Library of Medicine, National Institute of Occupational Health and Safety, National Institutes of Health, and the World Health Organization. He was also a member of the EPA Science Advisory Board. His active research is in chemical carcinogenesis, mathematical modeling, and estimation of human health risks. BYRON E. BUTTERWORTH, Vice Chairman, is chief of genetic tox- icology for the Chemical Industry Institute of Toxicology in Research Triangle Park, North Carolina. His numerous publications include papers on the development of new methods to determine the genotoxic effects of chemicals in the whole animal and in exposed individuals. He serves as an advisor on several national and international committees dealing with toxicology. He is a member of the American Association for Cancer Research and the Environmental Mutagen Society. Dr. Butterworth is also an adjunct associate professor in the Department of Pathology of the University of North Carolina in Chapel Hill. MELVIN E. ANDERSEN is a research pharmacologist, Toxic Hazards Division, Armstrong Aerospace Medical Research Laboratory, Wright- Patterson Air Force Base, Ohio. Dr. Andersen specializes in developing physiologically based models for examining the pharrnacokinetics and 439

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440 Committee Biographies pharmacodynamics of volatile chemicals. He is presently a member of the editorial board and in the past was associate editor of Toxicology and Applied Pharmacology. He is a member of the Society of Toxicology and a diplomate of the American Board of Toxicology and the American Board of Industrial Hygiene. JAMES V. BRUCKNER is associate professor of pharmacology and toxicology and director of the Toxicology Program at the University of Georgia. Dr. Bruckner is an environmental toxicologist whose research areas include development of in vitro testing systems for hepatorenal toxins, comparison of the relative pharmacokinetics and toxicity of inhaled and ingested organics, and investigation of the toxicity of halogenated hydrocarbons. Dr. Bruckner has served as consultant to state and federal agencies and to industry and as a member of expert panels for these groups. He serves on editorial boards of the Journal of Toxicology and Environ- mental Health, Toxicology, and Toxicology and Applied Pharmacology. SEYMOUR L. FREISS is president of Drill, Freiss, Hays, Loomis & Shaffer, Inc., a firm of consultants in toxicology. His research has been in the fields of physical biochemistry, pharmacology, toxicology, and chemical hazard assessment/safety evaluation. He has served as president of the Society of Toxicology, the International Union of Toxicology, and the certifying body, American Board of Toxicology, Inc. He has also served on the editorial boards of major journals in toxicology. MICHAEL A. GALLO is an associate professor and director of toxi- cology and environmental health in the Department of Environmental and Community Medicine at the University of Medicine and Dentistry of New JerseyRutgers Medical School, and associate director of the Rutgers University/Rutgers Medical School Joint Graduate Program in Toxicology. Dr. Gallo is associate editor of Drug and Chemical Toxicology, a member of the Board of Scientific Counselors of the National Toxicology Program, a member of the New Jersey Governor's Advisory Toxicology Panels on dioxin and radon, and chairs the Governor's Pesticide Control Council. He served as a member of the NRC Committee on Dnnking Water and Health, Volume 5, and currently serves on the NRC Committee on Com- plex Mixtures. Dr. Gallo's research interests address the cellular and molecular mechanisms of toxicity of dioxins, chlorinated pesticides, and the molecular interactions of photoactive compounds and tumor promoters as they relate to risk assessment. JOHN N. HATHCOCK is currently chief of the Experimental Nutrition Branch, Food and Drug Administration, and until recently was professor in the Department of Food and Nutrition, Iowa State University. Dr. Hathcock is a member of the American Institute of Nutrition and the Society of Toxicology and serves on the editorial boards of Nutrition Reviews and Drug-Nutrient Interactions. He has edited volumes on

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Committee Biographies 441 nutritional toxicology and drug-nutnent interactions and has served as a consultant to the Pesticide Tolerance Study Group of the Environmental Protection Agency. CLARK W. HEATH, JR., is director of the Bureau of Preventive Health Services at the South Carolina Department of Health and Environmental Control. He was formerly professor of Community Health at Emory Uni- versity and director of the Chronic Diseases Division, Center for Envi- ronmental Health, Centers for Disease Control. Dr. Heath is a physician epidemiologist with particular experience in the epidemiology of cancer, reproductive disorders, and environmental health. He is a fellow of the American Epidemiological Society, the Society for Epidemiologic Re- search, and the International Epidemiological Association. MICHAEL E. HOGAN is assistant professor in the Department of Molecular Biology at Princeton University. He received his undergraduate degree in biology at Dartmouth College, his Ph.D. from the Department of Molecular Biophysics and Biochemistry at Yale, and was a postdoctoral fellow of the Damon Runyon-Walter Winchell Cancer Fund at Stanford University in the Magnetic Resonance Laboratory (1979-19801. His prin- ciple field of interest is the physical biochemistry of carcinogen adducts with genetic material. DAVID I. JOLLOW is a professor of pharmacology and director of the Laboratory of Molecular Toxicology at the Medical University of South Carolina. For the past 15 years, Dr. Jollow has conducted research on the molecular mechanisms underlying tissue necrosis caused by drugs and other xenobiotic compounds. He is a member of the American Society for Pharmacology and Experimental Therapeutics, a past member and chairman of the Toxicology Study Section of the National Institutes of Health, and a councillor of the International Society for the Study of Xenobiotics. JEANNE M. MANSON is director of Reproductive and Developmental Toxicology at Smith Kline and French Laboratories, Philadelphia, Penn- sylvania. Dr. Manson also serves as an adjunct associate professor in teratology at the University of Cincinnati and Thomas Jefferson University in Philadelphia. She is a member of the National Toxicology Program's Board of Scientific Counselors and has served on the Science Advisory Board of EPA and the Advisory Council of NIEHS. Her research has addressed the developmental toxicity of drugs and environmental agents. FREDERICA P. PERERA is assistant professor of Environmental Sci- ences at the Columbia University School of Public Health. She is project director of several molecular epidemiology studies of chemical carcino- genesis in humans. Senior scientist at the Natural Resources Defense Council, Inc., from 1979 to 1983, Dr. Perera currently acts as a science advisor to that organization. She is senior author of a book on air pollution,

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442 Committee Biographies as well as articles on molecular epidemiology, risk assessment, and en- vironmental policy, and serves on advisory committees including the Na- tional Toxicology Program's Board of Scientific Counselors and the U.S. Environmental Program. MARVIN A. SCHNEIDERMAN is professor of biostatistics at the Uni- formed Services University of the Health Sciences, Bethesda, Maryland, and a private consultant in matters relating to environment and health. Until 1980 he was at the National Cancer Institute, first as a theoretical (research) statistician, later as associate director for Field Studies (Epi- demiology) and Statistics, and then as associate director for Science Policy. He has been on the editorial board of several journals. He was chairman of the Epidemiology Subcommittee of the first NRC Safe Drinking Water Committee. He is past chairman of COPSS (Committee of Presidents of Statistical Societies) and has served on the Board of Directors of the American Statistical Association and on the Council of the (International) Biometrics Society. He is the author of about 130 scientific papers and the editor of several books relating to the environment and health one in Russian, which was developed as a consequence of his being chairman of the U.S. group in a series of scientific exchanges with Soviet scientists on matters relating to the epidemiology of cancer. PETER S. SPENCER is professor of neuroscience and director of the Institute of Neurotoxicology at The Albert Einstein College of Medicine of Yeshiva University, The Bronx, New York. He is a member of the Board on Toxicology and Environmental Health Hazards of the NRC, a former member of its Committee on Toxicology, and past president of the specialty section on neurotoxicology of the Society of Toxicology. His research activities are focused on molecular and cellular mechanisms of chemical neurotoxicity.