Workshop Agenda

INSTITUTE OF MEDICINE VACCINE SAFETY FORUM

Workshop on Poliomyelitis Vaccines

Savoy Suites Georgetown

2505 Wisconsin Avenue, N.W. Washington, D.C.

Wednesday, June 7, 1995

7:30 a.m.

Registration desk opens

8:15

Setting the Stage: Alternatives for U.S. Policy on Polio Vaccines Richard B. Johnston, Jr., Chair, IOM Vaccine Safety Forum and Chair of Wednesday morning session

History and Current Status of Poliomyelitis Vaccines

8:30

General Overview, 1900–1995

Frederick C. Robbins, Case Western Reserve University

8:50

Current U.S. Status

Walter Orenstein, Centers for Disease Control and Prevention

9:15

Other American Experience

Ciro de Quadros, Pan American Health Organization

Ronald Gold, Hospital for Sick Children, Toronto

9:45

Global Experience

Stephen Cochi, Centers for Disease Control and Prevention

Poliomyelitis Vaccine Characteristics

10:45

Current Status of OPV

Peter Paradiso, Lederle-Praxis Biologicals



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Options for Poliomyelitis Vaccination in the United States: Workshop Summary Workshop Agenda INSTITUTE OF MEDICINE VACCINE SAFETY FORUM Workshop on Poliomyelitis Vaccines Savoy Suites Georgetown 2505 Wisconsin Avenue, N.W. Washington, D.C. Wednesday, June 7, 1995 7:30 a.m. Registration desk opens 8:15 Setting the Stage: Alternatives for U.S. Policy on Polio Vaccines Richard B. Johnston, Jr., Chair, IOM Vaccine Safety Forum and Chair of Wednesday morning session History and Current Status of Poliomyelitis Vaccines 8:30 General Overview, 1900–1995 Frederick C. Robbins, Case Western Reserve University 8:50 Current U.S. Status Walter Orenstein, Centers for Disease Control and Prevention 9:15 Other American Experience Ciro de Quadros, Pan American Health Organization Ronald Gold, Hospital for Sick Children, Toronto 9:45 Global Experience Stephen Cochi, Centers for Disease Control and Prevention Poliomyelitis Vaccine Characteristics 10:45 Current Status of OPV Peter Paradiso, Lederle-Praxis Biologicals

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Options for Poliomyelitis Vaccination in the United States: Workshop Summary 11:15 Current Status of IPV Carlton Meschievitz, Pasteur Mérieux Connaught 12:15 p.m. LUNCH Options for Poliomyelitis Vaccination   Chair, Wednesday afternoon session Russell Alexander, Seattle-King County Health Department 1:15 p.m. Benefits and Risks: Personal Experiences March of Dimes Historical Video John Salamone, Oakton, Virginia Lenita Schafer, Princeton, Massachusetts 1:40 Oral Poliovirus Vaccine—Benefits, Risks, and What Is Not Known Peter Wright, Vanderbilt University 2:20 Inactivated Poliovirus Vaccines—Benefits, Risks, and What Is Not Known Stanley Plotkin, Pasteur Mérieux Connaught 3:00 Sequential Use of IPV and OPV—Benefits, Risks, and What Is Not Known John Modlin, Dartmouth Medical School 3:50 Parental Choice—Benefits, Risks, and What Is Not Known Neal Halsey, Johns Hopkins University 4:00 No Vaccine—Benefits, Risks, and What Is Not Known D. A. Henderson, Johns Hopkins University 4:20 Modelling the Five Options Robert Kohberger, Lederle-Praxis Roland Sutter, Centers for Disease Control and Prevention 5:30 ADJOURN

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Options for Poliomyelitis Vaccination in the United States: Workshop Summary CENTERS FOR DISEASE CONTROL AND PREVENTION Workshop on Poliomyelitis Vaccines Savoy Suites Georgetown 2505 Wisconsin Avenue, N.W. Washington, D.C. Thursday, June 8, 1995 8:30 a.m. Introduction and Charge for the Day Jeffrey Davis, Chair, Advisory Committee on Immunization Practices and Chair, Thursday session Implementation Issues for Poliomyelitis Vaccination 8:40 Potential Schedules Integrated into Harmonized Vaccination—Present and Future Jacqueline Gindler, Centers for Disease Control and Prevention 9:00 Future Prospects with Combination Vaccines Kathryn Edwards, Vanderbilt University 9:20 Provider Perspectives, Public and Private Guthrie Birkhead, New York State Department of Health Richard Zimmerman, University of Pittsburgh Caroline Hall, University of Rochester 9:50 Parent Perspectives Kathi Williams, National Vaccine Information Center 10:00 Consumer and Ethical Issues Lawrence Gostin, Georgetown University Law Center and Johns Hopkins University 10:20 Liability and Compensation Issues Robert Weibel, Vaccine Injury Compensation Program John Brydon, Attorney, Long Beach, California 11:00 Cost-Benefit Assessment of the Options Mark Miller, Centers for Disease Control and Prevention

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Options for Poliomyelitis Vaccination in the United States: Workshop Summary 11:30 Discussion 12:15 p.m. LUNCH Considering the Options for Poliomyelitis Vaccination 1:45 p.m. Panel Summation Presentations OPV Only D. A. Henderson, Johns Hopkins University IPV Only Ronald Gold, Hospital for Sick Children, Toronto IPV-OPV Sequential Schedule Joseph Melnick, Baylor College of Medicine Informed Parental Choice Jessica Scheer, National Rehabilitation Hospital Research Center, Washington, D.C. No Vaccine Stephen C. Marini, Pennsylvania College of Chiropractic 2:20 Discussion 2:45 BREAK Discussion and Summary 3:00 Discussion of Unanswered Questions Jeffrey Davis, Chair, Advisory Committee on Immunization Practices 4:00 Summary of Workshop Presentations and Discussion Samuel Katz, Duke University 4:20 Discussion 5:00 ADJOURN