Environmental Tobacco Smoke: Measuring Exposures and Assessing Health Effects

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Environmental Tobacco Smoke: Measuring Exposures and Assessing Health Effects (1986)
Commission on Life Sciences (CLS)

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. "12 Exposure to Environmental Tobacco Smoke and Lung Cancer." Environmental Tobacco Smoke: Measuring Exposures and Assessing Health Effects. Washington, DC: The National Academies Press, 1986.

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Environmental Tobacco Smoke: Measuring Exposures and Assessing Health Effects

TABLE 12–4 Summary of Epidemiologic Studies of Risk Based on Exposure Assessed by Spouse Smoking Habits, When Available, or Smoking by the Household Cohabitants

Study No.	Study Authors	Location	Sex	Lung Cancers in “Exposed” Group		O–E	Var. of (O–E)	Risk^a	95% Confidence Limits
Study No.	Study Authors	Location	Sex	Obs.	Exp.	O–E	Var. of (O–E)	Risk^a	95% Confidence Limits
Case-Control Studies
1	Chan and Fung, 1982	Hong Kong	F	34	37.7	−3.7	13.01	0.75	0.44	1.30
2	Trichopoulos et al., 1983	Greece	F	38	29.3	8.7	11.70	2.13	1.18	3.78
3	Correa et al., 1983	U.S.A.	F M	14 2	10.6 1.2	3.4 0.8	4.75 0.98	2.03 2.29	0.83 0.31	5.03 16.50
4	Kabat and Wynder, 1984	U.S.A.	F M	13 5	13.7 5.0	−0.7 0.0	3.06 1.52	0.79 1.00	0.26 0.20	2.43 4.90
5	Buffler et al., 1984	U.S.A.	F M	33 5	34.1 6.6	−1.1 −1.6	4.78 2.37	0.80 0.50	0.32 0.14	1.99 1.79
6	Garfinkel et al., 1985	U.S.A.	F	92	89.5	2.5	22.33	1.12	0.74	1.69
7	Pershagen et al., in press	Sweden	F	33	29.6	3.4	13.88	1.28	0.75	2.16

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232

Front Matter (R1-R8)

Contents (R9-R14)

Executive Summary (1-12)

1 Introduction (13-22)

Part I: Physicochemical and Toxicological Studies of Environmental Tobacco Smoke (23-24)

2 The Physicochemical Nature of Sidestream Smoke and Environmental Tobacco Smoke (25-53)

3 In Vivo and In Vitro Assays to Assess the Health Effects of Environmental Tobacco Smoke (54-62)

Part II: Assessing Exosures to Environmental Tobacco Smoke (63-64)

4 Introduction (65-68)

5 Assessubg /Exposures to Environmental Tobacco Smoke in the External Environment (69-100)

6 Assessing Exposures to Enviromental Tobacco Smoke Using Questionnaires (101-119)

7 Exposure-Dose Relationship for Environmental Tobacco Smoke (120-132)

8 Assessing Exposures to Environmental Tobacco Smoke Using Biological Markers (133-160)

Part III: Health Effects Possibly Associated with Exposure to Environmental Tobacco Smoke by Nonsmokers (161-162)

9 Introduction (163-165)

10 Sensory Reactions To and Irritation Effects of Environmental Tobacco Smoke (166-181)

11 Effects of Exposure to Environmental Tobacco Smoke on Lung Function and Respiratory Symptoms (182-222)

12 Exposure to Environmental Tobacco Smoke and Lung Cancer (223-249)

13 Cancers Other than Lung Cancer (250-256)

14 Cardiovascular System (257-268)

15 Other Health Considerations in Children (269-276)

Appendixes (277-278)

Appendix A: Guidelines for Public and Occupational Chemical Exposures to Materials that are Also Found in Environmental Tobacco Smoke (279-283)

Appendix B: Method of Combining Data From Studies of Environmental Tobacco Smoke Exposure and Lung Cancer (284-288)

Appendix C: Adjusments to Epidemiologic Estimates of Excess Lung Cancer in Persons Exposed to Environmental Tobacco Smoke (289-293)

Appendix D: Risk Assessment- Exposure to Environmental Tobacco Smoke and Lung Cancer (294-338)