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TABLE 14–2 Resting Acute Cardiovascular Effects in Nondiseased Humans of Exposure to Environmental Tobacco Smoke

Authors

Study Population

Conditions

Results

Measured Variable

Before

After

Luguette et al., 1970

40 children

Room: 9 m3

No. cig.: 6

Time: 15 min

Heart rate

Blood pressure

89

116/67

97

120/72

Harke and Bleichert, 1972

10

Room: n.g.

No. cig.: 150

Time: 20 min

Heart rate

Blood pressure

Skin temperature (−°C/min)

72±8

123/84

0

74±12

121/84

0.0273

Rummel et al., 1975

56

Room: 30 m3

No. cig.: 6–8

Time: 20 min

Heart rate

Blood pressure

72±10

117/71

71±11

117/71

Hurshman et al., 1978

8

Room: n.g.

No. cig.: 2–6

Time: 10 min

Heart rate

Blood pressure

73

107/67

79

114/68

Pimm et al., 1978

10 males

10 females

Age=22.3

Room: 14.6 m3

No. cig.: 7

Time: 2 h

Heart rate

84(F)

77(M)

80(F)

70(M)

CO, or ETS need to be separately studied. In addition, consideration needs to be given to persons of different sensitivity or vulnerability.

Healthy Subjects

Table 14–2 lists studies that report on the consequences of exposure of nondiseased individuals to ETS for periods up to 2 hours under experimental, resting conditions. There were no significant changes noted in heart rate or blood pressure in school-aged children or in adult men and women.

Two studies evaluated the physiologic responses to exercise with and without exposure to ETS. In the first, Pimm et al. (1978) (see also Table 14–2) had subjects perform a 7-minute progressive exercise test on an electronic bicycle ergometer. During exercise, the women had higher heart rates after exposure to ETS when compared with control conditions (differences of 6.3 beats per minute at 2 minutes and 4.5 beats per minute at 7 minutes, p<0.01). The recovery heart rates were not significantly different. The men, however, showed little difference between test and



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