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Environmental Tobacco Smoke: Measuring Exposures and Assessing Health Effects (1986)
Commission on Life Sciences (CLS)

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. "Appendix B: Method of Combining Data From Studies of Environmental Tobacco Smoke Exposure and Lung Cancer." Environmental Tobacco Smoke: Measuring Exposures and Assessing Health Effects. Washington, DC: The National Academies Press, 1986.

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Environmental Tobacco Smoke: Measuring Exposures and Assessing Health Effects

TABLE B-1 Passive Smoking and Lung Cancer: Observed Numbers Used to Calculate Values in Table 12–4a

Type of Study

Study Authors

Sex

Spouse Smoker

Spouse Nonsmoker

Risks

Cases (a)

Controls (b)

Cases (c)

Controls (d)

Computed

Published

CC

Chan and Fung, 1982

F

34

66

50

73

0.75

CC

Trichopoulos et al., 1983

F

38

81

24

109

2.13

2.4, 3.4

CC

Correa et al., 1983

F

M

14

2

61

26

8

6

72

154

2.03

2.29

2.00

2.07

CC

Kabat and Wynder, 1984

F

M

13

5

15

5

11

7

10

7

0.79

1.00

CC

Buffler et al., 1984

F

M

33

5

164

56

8

6

32

34

0.80

0.50

0.78

0.52

CC

Garfinkel et al., 1985

F

92

266

42

136

1.12

1.12

CC

Pershagen et al., in press

F

33

150

34

197

1.28

1.2

CC

Akiba et al., 1986

F

M

73

3

188

9

21

16

82

101

1.48

2.45

1.5

1.8

CC

Koo et al., 1985

F

51

66

35

70

1.54

1.64

CC

Lee et al., 1986

F

M

22

8

45

14

10

7

21

16

1.03

1.30

1.00

1.30

PRO

Garfinkel, 1981

F

88

127,164

65

49,422

1.27, 1.10

PRO

Gillis et al., 1984

F

M

6

4

1,388

306

2

2

521

515

1.00

3.25

PRO

Hirayama, 1984

F

M

146

7

69,287

1,003

37

57

21,858

19,222

1.45, 1.91

2.25

ABBREVIATIONS: CC=Case-Control

PRO=Prospective

aFor the calculations, (a) through (d) are used for case-control studies and published RR are used for prospective studies.

Page
285
Front Matter (R1-R8)
Contents (R9-R14)
Executive Summary (1-12)
1 Introduction (13-22)
Part I: Physicochemical and Toxicological Studies of Environmental Tobacco Smoke (23-24)
2 The Physicochemical Nature of Sidestream Smoke and Environmental Tobacco Smoke (25-53)
3 In Vivo and In Vitro Assays to Assess the Health Effects of Environmental Tobacco Smoke (54-62)
Part II: Assessing Exosures to Environmental Tobacco Smoke (63-64)
4 Introduction (65-68)
5 Assessubg /Exposures to Environmental Tobacco Smoke in the External Environment (69-100)
6 Assessing Exposures to Enviromental Tobacco Smoke Using Questionnaires (101-119)
7 Exposure-Dose Relationship for Environmental Tobacco Smoke (120-132)
8 Assessing Exposures to Environmental Tobacco Smoke Using Biological Markers (133-160)
Part III: Health Effects Possibly Associated with Exposure to Environmental Tobacco Smoke by Nonsmokers (161-162)
9 Introduction (163-165)
10 Sensory Reactions To and Irritation Effects of Environmental Tobacco Smoke (166-181)
11 Effects of Exposure to Environmental Tobacco Smoke on Lung Function and Respiratory Symptoms (182-222)
12 Exposure to Environmental Tobacco Smoke and Lung Cancer (223-249)
13 Cancers Other than Lung Cancer (250-256)
14 Cardiovascular System (257-268)
15 Other Health Considerations in Children (269-276)
Appendixes (277-278)
Appendix A: Guidelines for Public and Occupational Chemical Exposures to Materials that are Also Found in Environmental Tobacco Smoke (279-283)
Appendix B: Method of Combining Data From Studies of Environmental Tobacco Smoke Exposure and Lung Cancer (284-288)
Appendix C: Adjusments to Epidemiologic Estimates of Excess Lung Cancer in Persons Exposed to Environmental Tobacco Smoke (289-293)
Appendix D: Risk Assessment- Exposure to Environmental Tobacco Smoke and Lung Cancer (294-338)