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B Extract from Statement of Work of DOD/NAS Contract SCOPE The CTR program is working with the Russian Federation to expedite the dismantlement of weapons of mass destruction, to encourage nonproliferation, and to promote conversion of military capabilities to peaceful, civilian applications. These efforts will support the CTR program by developing a cooperative support and research program to assist in conversion of the FSU BW personnel and facilities by redirecting work to public health and other peaceful, civilian research programs. The program will be executed by the NAS. NAS, the National Academy of Engineering, TOM, and the National Research Council will collaborate on this project. OBJECTIVES The basic objective of this effort is to support the conversion of former Soviet BW research personnel to work on international public health issues. The specific objective is to engage Russian BW researchers in continuing collaborative projects with the West as part of the global effort for research, surveillance, and monitoring of new, emerging and reemerging diseases. Some existing diseases that might be subjects for cooperative work include hantavirus and broader classes of hemorrhagic fevers, tick- borne encephalitis, malaria, tuberculosis, and human immunodeficiency virus (HIV)/ATDS. The specific types of research involved could include work on (1) surveillance and monitoring methods, (2) studies of pathogenesis, (3) diagnostic tests, (4) treatments, and (5) new vaccines.