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OCR for page 230
SUBJECT INDEX
Abortions, reporting of, 9
spontaneous, 18
therapeutic (induced) , 19, 61, 76
Acetabulum, dysplasia of, 15, 102, 104
"Accumulation factor," in man, 212
Age, maternal
allowance for, in analysis, 76
differences in irradiation subclasses, 55
Age effects, maternal
onbirthweight, 132, 148
on death during first 9 months, 152
on growth and development, 165
on malformation frequency, 105, 189
on sex ratio, 89
on stillbirth frequency, 119
Ainu, 21
Americans, in Nagasaki, 23
Analytic methods, general
attribute data
"interactions," 78, 162
"main eRects," 78, 162
measurement data, 83, 84
Analytic methods, specific
analysis of dispersion, 168
Bartlett's test, 137, 175, 179
concomitant variation, approach to, 73
confidence limits, 197
covariance analysis, 75, 133, 137
determinants of matrices, 168
F test, 179
heterogeneity, within-cell, 85, 133, 137, 168, 175,
179
index of absolute difference, 105, 185
L statistic, 148, 170
means, multivariate, 164, 165, 168, 170, 175, 179
"omnibus" tests, 84
"portmanteau" tests, 84
power curves, 197, 198
pyramidal handling of data, 73
regression, 82, 132, 133, 148
significance test, one-tailed, 89, 198
variance, generalized, 164, 168, 175, 179
variance analysis, 82, 86, 133, 137, 150, 157, 175
Wilks' test, 168
Anamnestic data, reliability of, 14
Anthropometric studies
genetic component in, 164
measurements obtained, 164
variation, effect of maternal age on, 165
parity, 1 65
radiation, 165, 196
Armed Forces Institute of Pathology, 47
Atomic Bomb Casualty Commission, 2
Atomic bombs, mortality from, 28
radiation from, 33
Austrians, in Nagasaki, 23
Autopsy program, 9
description of, 184
of Hayashi, 189
237
randomness of autopsies, 184
type of data, 187
Biases, of sampling, 191
see also "comparability of irradiation subclasses"
Birth injury
death during first 9 months, 152
effect on stillbirth rate, 119
Birth rates, Japanese, 19
Birthweight
accuracy of, 131
effect on, of maternal age, 132, 148
economic status, 131, 148
nutrition, 131
parental radiation, 132, 196
parity, 132, 148
year of birth, 148
genetic component in, 131
"Black market," 4, 132
Blood group (A-B-O) frequencies, 25
Cataracts, radiation, 33, 69
Chest circumference of child, in relation to parental
radiation, 164
Chikuzen type, of Japanese, 171
China, 21
Chinese, in Nagasaki, 22, 28
Chi-square, 82
factorial, 82
in analysis of age and parity effects on malforma-
tions, 105
Christianity, ban against, 22, 24
Codes for data, 18
Genetics Long Form, 221
Genetics 9-Months Follow-up, 225
Genetics Short Form, 218
Committee for the Investigation of the Effects of the
Atomic Bombs (Japanese), 2, 20
Committee on Atomic Casualties, 1, 19, 87
Comparability of irradiation subclasses
age, 55, 73
background, 71, 192
consanguinity, 53, 73
dilatation and curettage of uterus, 61,73
economic status, 59, 73
induced abortions, 61, 73
parental cooperation, 63
parity, 55, 73
positive serological test for syphilis, 61, 73
repeat registrations, 63, 73
sequelae of exposure, 69
year to year changes in proportions, 69
Confidence limits, of attribute data, 196
Congenital defect see "malformation, congenital"
Consanguinity
allowance for, in analysis, 76
differences, in exposure subgroups, 53, 73
effect of Christianity on, 55
Controls, use of exposed persons as, 86
see also "comparability of irradiation subclasses"
Cooperation, of parents, 63
OCR for page 230
238
Covariance analysis, 75, 133, 137
Cytogenetic studies, 18
Danes, in Nagasaki, 23
Death, from birth to 9 months of age
frequency of, as affected by birth injury, 152
congenital syphilis, 152
maternal age, 152
maternal nutrition, 152
parental radiation, 157, 196
parity, 152, 162
genetic component of, 151
neonatal, definition of, 151
operating characteristic curve of, 198
Degrees of freedom
in analysis of attribute data, 81
Deshima, 22, 24
"Disaster effect," vs. "radiation eRect," 33, 150, 192
Distance, in relation to symptoms, 41
Distance-dosage relationship, 36, 46
Drosophila, 199, 203, 204, 208, 209, 212, 213, 216
mutation rate, induced, 211
mutation rate, spontaneous, 206
number of genes in, 212
Dutch, in Nagasaki, 22, 23, 24
Economic status, allowance for, in analysis, 76
effect on birthweight, 131
effect on frequency of autopsy, 186
of control and irradiated, 59
English, in Nagasaki, 22, 23
Errors, clerical, 15
diagnostic, 15
Exposure to radiation, sequelae of
cataracts, 33, 69
leukemia, 33, 69
Finland, 21
Formosa, 21
Franciscans, in Nagasaki, 22
French, in Nagasaki, 23
Funnel chest, 102
Gamma rays, importance in dosage, 52
Genes see also "accumulation factor"
additive effects of, 213
number in Drosophila, 212
number in man, 212, 217
Genetic damage, indicators of, 3, 5, 72
Genetics Conferences
first, 2, 217, 231
second, 19
Genetics Long Form, 9, 14, 61, 93, 221
Genetics 9-Months Follow-up, 15, 225
Genetics Short Form, 5, 9, 44, 53, 61, 218
Guinea pig, 213
radiation of, effect on birthweight, 203
on growth and development, 203
on neonatal death rate, 203
Goa, 21
Government, Japanese, 3
Hawaii, 28, 173
Head circumference of child, in relation to parental
radiation, 164
Heart disease, congenital, 15, 102
Hernia, inguinal, 15, 102
Heterogeneity, within exposure cells, 85, 133, 137,
168, 175, 179
Honshu, 21
Sz~bjer~ Index
Indonesia, 21
Ishikawa type, of Japanese, 171
Japan Science Council, 34, 189
Japanese, origin of, 21
physical types of, 171
Jesuits, in Nagasaki, 21
Korea, 21, 173
"Korean colony," in Hiroshima, 28
Kyushu, 21
LD50, man, 45
Length of child, in relation to parental radiation, 164
Leucopenia, following irradiation, 46, 50
Leukemia, 33, 69
Macao, 21, 24
Malaysia, 21
Malformation, congenital see also under specific
type
accuracy of diagnosis, 99
autopsy studies of, 184
definition of
major, 99
minor, 99
frequency, in relation to parental radiation, 195
at age 9 months, 115
at birth, 110
specific types, 117
frequency of, as affected by maternal age, 105
nutrition, 110
parity, 105
viral infections, 110
operating characteristic curve of, 198
opportunities for concealment, 63
study of Macht and Lawrence, 202
types encountered, in ABCC study, 100
comparison, in Hiroshima and Nagasaki, 102
in other studies on Japanese, 101
Manchuria, 21, 172
Marshall Islands, 49
Meiji era, 22
Mental defect, severe, 102, 104
Midwives, 4, 5, 9
Midwives Association, 5
Ministry of Welfare, Japanese, 2
Miscarriages, reporting of, 9
Mongolism, 110
Mouse
radiation of, effect on malformation frequency, 201
on neonatal death rate, 203
on sex ratio, 200
on stillbirth frequency, 202
sterility following irradiation, 200
Mutation rates, induced by radiation, 3
in Drosophila, 211
in man, 211, 217
in the mouse, 210
Mutation rates, spontaneous, 3, 205
in Drosophila, 208
in man, 209
in the mouse, 209
Mutations, types of
"detrimentals," 164
"invisibles," 131
lethal, 88,118,204,205
ratio of types, 206, 207
sex-linked, 88, 203
"visibles," 104,204,205
OCR for page 230
Subject Index
Nagasaki Medical School, 29, 102, 184, 188, 189
National Academy of Sciences-National Research
Council (U.S.), 1, 3, 19, 20
National Institute of Health, Japanese, 2, 5, 20
National Research Council, Japanese, 2
Neonatal death see "death, neonatal"
Neutrons, importance in dosage, 51, 52
"Nine-months program," description of, 14
Non-orthogonality, 86, 157
Nutrition, maternal, effect on
birthweight, 132
death during first 9 months, 152
malformation frequency, 105
size of adult, 172
stillbirth frequency, 119
Okayama type, of Japanese, 171
Operating characteristic curves, 198
Parity
allowance for, in analysis, 76
differences, in irradiation subclasses, 55
Parity effects
on birthweight, 132, 148
on death during first 9 months, 152
on growth and development, 165
on malformation frequency, 105
on sex ratio, 89
on stillbirth frequency, 120
Plutonium-239, 28
Polynesia, 21
Portuguese, in Japan, 21, 24
Prefecture, definition of, 23
Pregnancy registration, Japanese, 5
completeness of, 7
repeat, 63, 77
Radiation, indicators of genetic effects of, 3, 5, 72
Radiation, residual, 33, 189
Radiation, symptoms of
diarrhea, 36
epilation, 29, 36, 47
oropharyngeal lesions, 29, 36, 47
petechiae, 29, 36, 47
Radiation categories
definition of
by ABCC, 44
by Hayashi, 189
dosage in, 45, 50
Radiation Census, 44
Radiation history, 5, 9, 38
validity of, 44
Radiation sickness, syndrome of, 34
Ration system, 4
Registration, of pregnancy see "pregnancy registra
tion"
Rejected observations, justification, 77
Rockefeller Foundation, 20
Roentgen, 45
Roentgen equivalent physical, 45, 46, 51, 203
Russia, 21
Russians, in Nagasaki, 23, 25
Ryukyu Islands, 21
239
Sampling, balanced, 75
Satsuma type, of Japanese, 171
Selection, natural, in man, 213
Sequelae, late, of exposure to bombs, 69
Sex differences, in anthropometrics, 170
in birthweight, 135
in indicator values, 192
in malformation frequency (absent), 110
in neonatal death rate, 157
in stillbirth frequency (absent), 124
Sex ratio
effect of concomitant variation on, 89
effect of irradiation of parents on, 89, 194
genetic control of, 88
operating characteristic curves of, 198
study of Macht and Lawrence, 201
Shielding, 36, 50
in relation to symptoms, 41, 42
Siberia, 21
Sinus, pilonidal, 15, 104
Spanish, 22
Sterility, in mouse following radiation, 200
Stillbirth
definition of, 118
frequency of, as affected by
birth injury, 119
congenital syphilis, 119
maternal age, 120
nutrition, 119
parental radiation, 124, 196
parity, 1 20
paternal age, 120
genetic component in, 118
operating characteristic curve of, 198
study of Macht and Lawrence, 203
Sweden, 21
Syphilis, maternal, 9
allowance for, in analysis, 76
different rates, in irradiation subclasses, 61
effect on death during first 9 months, 152
effect on stillbirth frequency, 119
relation to frequency of autopsy, 187
"Ten-per cent sample," 9
Tokugawa Shogunate, 22, 24
U.S. Army of Occupation, 3
U.S. Army-Navy Joint Commission, 2, 47, 49
U.S. Atomic Energy Commission, 1, 3, 19, 87
"Unregistered Series," 7
Uranium-235, 28
Uterus, dilatation and curettage of, 61
allowance for, in analysis, 76
Variance analysis, 82, 86, 133, 137, 150
Variances, test for equality of, 84
Viral diseases
effect on malformation frequency, 105
Weight of child, in relation to parental radiation,
164
X-chromosome, 88, 204
Y-chromosome, 88
OCR for page 230
NAME INDEX
Alexander, M. L., 208, 211, 230
Anderson, R. C., 53, 234
Antonov, A. N., 59, 110, 131, 230
Armitage, P., 20
Balfour, M. I., 59, 230
Barnett, H. L., 234
Bartlett, M. S., 175, 179, 230
Beadle, G. W., 1, 2, 19
Beardsley, R., 21, 230
Bell, M., 231
Bellows, M. T., 233
Bernstein, M., 89, 230
Block, M., 1
Bond, V. P., 50, 230
Bonnier, G., 208, 230
gorges, W., 33, 69, 231
Bowers, J. Z., 36, 235
Box, G. E. P., 84, 179, 230
Boxer, C. R., 24, 230
Boyd, W. C., 28, 230
Bradshaw, E. S., 55, 234
Brandt, A. E., 20, 82
Brewer, R., 53, 234
Brinkley, F., 21, 230
Bronk, D. W., 1
Brown, A., 231
Brues, A., 1
Burke, B. S., 59, 230
Butterfly, Madame, 25
Carter, C., 55, 105, 230
Charles, D. R., 2, 19, 201, 202, 230
Ciocco, A., 55, 89, 230
Cochran W. G.. 82 230
,
Coffey, V. P., 105, 230
Cogan, D. G., 33, 69, 230
Collins, V. P., 49, 230
Connell, F. H., 19
Cox, G., 86
Craig, C. C., 19, 20
Cronkite, E. P., 50, 230
Crow, J. F., 203, 231
Danforth, C. H., 2
Davidson, P., 20
Dean, R. F. A., 59, 231
Dobzhansky, T., 209, 231
Dunham, C. L., 50, 230
Dwyer, P. S., 20
Ebbs, J. H., 59, 231
Eisenhart, C., 82, 231
Evans, R. D., 210, 211, 212, 231
Falk, R., 206, 231
Falls, H. F., 213, 234
Fillmore, P. G., 69, 231
Fisher, R. A., 84, 231
Folley, J. H., 33, 69, 231
Forrestal, J. T., 1
Glass, H. B., 208
Gordon, J. E., 55, 233
Green, E., 20
.
240
Gruenwald, P., 105, 231
Hadorn, E., 202, 231
Haldane, J. B. S., 209, 211, 217, 231
Hammond, E. C., 234
Harris, H., 85, 231
Harris, T., 22
Hasebe, K., 171, 231
Hayasl~i, I., 184, 188, 189, 190, 191, 231
Hechter, H., 50
Hegnauer, H., 55, 231
Hempelmann, L. H., 36, 45, 49, 231
Henshaw, P. S., 1
Hertwig, P., 200, 202, 203, 231
Hill' B., 20
Hoffman, J. G., 36, 45, 49, 231
Holmes, R., 98
House, V. L., 213, 231
Hsiao, B., 20
Hulse, F. S., 171, 232
Ingalls, T. H., 102, 234
Ives, P. T., 208, 211, 232
Izumi, T., 23, 232
Jessop, W. J. E., 105, 230
Johnson, H., 20
Kaempfer, E., 22, 24, 171, 232
Kalmus, H., 200, 232
Karn, M. N., 55, 131, 232
Kastenbaum, M., 20, 69, 233, 234
Kelley, H. C., 20
Kendall, M. G., 86, 232
Keosian, J., 216, 232
Kerkis, J. J., 206, 232
Kimura, S., 33, 69, 230
Kirk, N. T., 1
Kirkwood, J. B., 102, 234
Kitamura, S., 234
Kiyono, K., 21, 232
Kobayashi, R., 20
Kodani, M., 18, 53, 234
Komai, T., 20
Koya, Y., 19, 232
Krooth, R., 20, 75, 105, 185, 214, 232
Kuji, V., 101
Kurasaki, H., 69, 232
Lamphiear, D. E., 20
Landtman, B., 55, 105, 232
Lange, R. D., 33, 69, 232, 233
Lawrence, P. S., 200, 202, 203, 232
Lefevre, G., 208, 232
Lerner, I. M., 206, 232
LeRoy, G. V., 47, 232, 234
Liebow, A. A., 234
Lisco, H., 36, 45, 49, 231
Loeffler, R. K., 49, 230
Lorenz, E., 69, 232
Lowe, C. R., 55, 89, 232
Lucas, H. C., 20, 74
Luning, K. G., 208, 230
Lyon, G. M., 1
, . , i
OCR for page 230
Name lade
Macht, S. H., 200, 202, 203, 232
MacMahon, B., 55, 233
Maki, H., 20
Martin, S. F., 33, 69, 230
Matsubayashi, I., 3
Matsumoto, S., 4, 233
Matsumura, A., 171, 233
Matsunaga, H., 69, 232
Matsuoka, S., 69, 232
McCarthy, D., 105, 230
McDonald, D. J., 234
McIntosh, R., 104, 233
McKeown, T., 55, 89, 232, 234
Meerdervoort, P., 22
Merritt, K. K., 233
Metrakos, J. D., 200, 232, 235
Millis, J., i31, 233
Mitani, S., 101
Moloney, W. C., 33, 69, 232, 233
Morton, J., 19
Morton, N., 131, 233, 234
Mourant, A. E., 28, 233
Moyle, W. J., 231
Muller, H. J., 2, 203, 206, 207, 208, 210, 211, 212,
213, 215, 216, 233
Munro, N. G., 21, 233
Murdoch, J., 21, 24, 233
Murphy, D. P., 202, 233
Myers, R. J., 55, 233
Nachtsheim, H., 209, 233
Nagai, I., 20
Neel, J. V., 1, 2, 19, 45, 53, 55, 96, 208, 209, 210,
213, 233, 234
Nickson, J. J., 49, 234
Nixon, W. C. W., 59, 234
Novitski, E., 55, 89, 234
Olkin, I., 20
Oughterson, A. W., 1, 33, 233
Parkes, A. S., 200, 234
Penrose, L. S., 20, 55, 131, 215, 232, 234
Perry, Commodore, 22, 25
Phelps, L. V., 7, 20
Plough, H., 19
Prindle, R. A., 102, 234
Rao, C. R., 20, 82, 86, 137, 168, 175, 234
Record, R. G., 55, 234
Reed, T. E., 209
Rhoads, C. P., 1
Rice, R. G., 55, 236
Richards, M. R., 233
Ritterhoff, R. K., 208
Rivers, T. M., 1
Robson, E., 131, 234
Rosenbaum, J. D., 234
Roy, S. N., 78, 234
Russell, W. L., 199, 200, 201, 202, 210, 211, 234
Salber, E. J., 55, 234
Sams, C. F., 2, 20
Samuels, M. H., 233
Sansom, G. B., 21, 24, 234
Sasano, A., 23, 234
Schneider, B. A., 234
Schneidewind, J., 20
Schull, W. J., 19, 54, 105, 208, 209, 210, 234
241
Schultz, J., 207, 234
Scott, W. A., 231
Seijas, B., 20
Seng, Y. P., 132, 233
Sevitt, S., 184, 188, 191, 23S
Shapiro, H. L., 172, 235
Silverberg, M., 200, 232
Sinskey, R. M., 33, 69, 235
Slatis, H. M., 210, 211, 212, 235
Smith, C. A., 59, 110, 131, 235
Smith, C. A. B., 85, 231
Smith, H. F., 20
Snedecor, G. W., 86, 235
Snyder, L. H., 2, 19
Spassky, B., 209, 231
Spassky, N., 209, 231
Spencer, W. P., 203, 207, 235
Spuhler, J. N., 212, 235
Stern, C., 19, 20, 203, 207, 235
Stevenson, S. S., 55, 230, 236
Strandskov, H. H., 89, 202, 203, 235
Stuart, H. C., 230
Sturtevant, A. H., 211, 235
Sutherland, I., 55, 235
Suzuki, M., 234
Takeshima, K., 234
Taylor, G., 19
Tessmer, C. F., 19
Thunberg, K. P., 25, 235
Tietze, C., 88, 235
Timofeeff-Ressovsky, N. W., 203, 206, 235
Tisdall, F. F., 231
Tomonaga, M., 69, 232
Trasler, 13. G., 200, 235
Tsuzuki, M., 20
Ullman, J., 20
Ullrich, F., 1
Valencia, J. I., 208
Valencia, R. M., 208
Vor der Bruegge, C. F., 36, 235
Wallace, B., 216, 235
Wallis, W. A., 73, 235
Warkany, J., 105, 110, 235
Warren, S. L., 1, 34, 235
Warren, Sh., 1, 34, 36
Weed, L. H., 1
Westergaard, M., 212, 235
Whipple, G. H., 1
Wilks, S. S., 86, 179, 235
Wilson, R. R., 34, 46, 236
Wishart, J., 137, 236
Wood, J., 234
Woodbury, L., 43, 98, 236
Woolley, W., 24, 236
Worcester, J., 55, 230, 236
Wright, S., 210, 211, 213, 236
Wright, S. W., 69, 232, 234, 236
Yamawaki, T., 33, 69, 231, 232
Yamazaki, J., 234
Yates, F., 86, 232
Yerushalmy, J., 55, 153, 232
Yesley, G., 20
Zelle, M., 19
Zirkle, R. E., 1