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PREFACE The Conference on Hemoglobin was held by the Division of Medical Sciences, National Academy of Sciences-National Research Council, as a result of discussions within its Subcommittee on Blood and Related Problems. The members of the Subcommittee felt that the time was ripe for a compre- hensive review of research on hemoglobin, similar to that which had been held in Cambridge, England, in 1948 in honor of Sir Joseph Barcroft. Chairmen of the various sessions were Drs. John T. Edsall, Irving M. London, and George E. Cartwright, each of whom has been helpful in editing his respective section of the Proceedings. Within the Division of Medical Sciences, staff responsibility for planning and conducting the Conference was borne by Dr. Margaret H. Sloan and Dr. fames R. Weisizer with the help of Mrs. Mary Freeman and Mrs. Phyllis Danielson. The manuscript and illustrations of these Proceedings were prepared for publication by Mr. Frank At. Holz, under the supervision of Dr. Weisiger. Some papers have been revised by the editors, and much of the discussion has been rearranged in the interest of logical association and continuity. Special acknowledgment is due to Dr. Hans T. Cahnmann, Dr. Harvey A. Itano, and Dr. James V. Neel for their assistance with various sections. The Subcommittee felt that, insofar as possible, the contents of this volume should represent the material actually available to the participants at the time of the Conference. On this basis the editors have regretfully excluded one paper that was not received in time for presentation. On the other hand, a paper that could not be presented for lack of time is included, since copies had been circulated in advance of the meeting. It has also proved necessary to omit the remarks of one discussant, from whom the editors were unable to obtain illustrations needed for their interpretation. In conclusion, the Division wishes to express its deep appreciation for the willing help and encouragement of the National Heart Institute, whose grant (No. H-2896) underwrote the costs of holding the Conference and of publishing these Proceedings. to . 111

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