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OCR for page R1
Information for Women About the Safety of Silicone Breast Implants
Information for Women About the Safety of Silicone Breast Implants
Martha Grigg, Stuart Bondurant, Virginia L. Ernster, and Roger Herdman, Editors
INSTITUTE OF MEDICINE
NATIONAL ACADEMY PRESS
Washington, D.C.
OCR for page R2
Information for Women About the Safety of Silicone Breast Implants
The project from which this publication was derived, Safety of Silicone Breast Implants, was carried out by a committee of the Institute of Medicine. The members of the committee responsible for the report were chosen for their special competences and with regard for appropriate balance.
Support for the project was provided by the National Institute of Arthritis and Musculoskeletal and Skin Diseases of the National Institutes of Health under Task Order No. 36, Contract No. N01-OD-4-2139.
Library of Congress Cataloging-in-Publication Data
Information for women about safety of silicone breast implants / Martha Grigg ... [et al.], editors ; Institute of Medicine.
p. ; cm.
Derived from Safety of silicone breast implants.
Includes bibliographical references and index.
ISBN 0-309-06593-3
1. Breast Implants—Complications. 2. Silicones—Toxicology. 3. Mammaplasty. I. Grigg, Martha. II Institute of Medicine (U.S.)
[DNLM: 1. Breast Implants—adverse effects—Popular Works. 2. Silicone Gels—adverse effects—Popular Works. WP 910 I43 2000]
RD539.8 .I54 2000
618.1′90592—dc21
99-058759
To obtain additional copies of Information for Women About the Safety of Silicone Breast Implants
For a single copy free of charge, please contact Y-me National Breast Cancer Organization, 212 W. Van Buren Street, Ste. 500, Chicago, IL 60607, (800) 221-2141 (hotline), (312) 294-8597 (fax).
For two or more copies, please contact
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, 2101 Constitution Avenue, NW, Lockbox 285, Washington, DC20055,(888) 624-8422 (toll-free),(202) 334-3313 (Washington metropolitan area), (202) 334-2451 (fax), www.nap.edu.
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To obtain additional copies of Safety of Silicone Breast Implants (ISBN 0-309-06593-3; 560 pages) from which the current publication is derived, please contact National Academy Press (at the address above). Price: $49.00 each plus $4.50 for the first book and $.95 for each additional book for shipping and handling.
The full text of both publications is available online at www.nap.edu.
For more information about the Institute of Medicine, visit the IOM home page at www.iom.edu .
Copyright 2000 by the National Academy of Sciences . All rights reserved.
INSTITUTE OF MEDICINE
Division of Health Promotion and Disease Prevention
2101 Constitution Avenue, N.W.
Washington, DC 20418
OCR for page R3
Information for Women About the Safety of Silicone Breast Implants
COMMITTEE ON THE SAFETY OF SILICONE BREAST IMPLANTS
STUART BONDURANT, M.D.
(Chair),
is a
Professor of Medicine
at the
University of North Carolina at Chapel Hill
VIRGINIA L. ERNSTER, Ph.D.
(Vice Chair),
is a
Professor of Epidemiology and Biostatistics
at the
University of California at San Francisco
MARGIT L. BLEECKER, M.D., Ph.D.,
is the
Director
of the
Center for Occupational and Environmental Neurology in Baltimore, Maryland
DIANE V. DADO, M.D., is an
Associate Professor of Surgery and Pediatrics
at
Loyola University Medical Center in Chicago
CARL J. D'ORSI, M.D.,
is a
Professor of Radiology
at the
University of Massachusetts Medical Center in Worcester
JOANN G. ELMORE, M.D., M.P.H.,
is an
Associate Professor of Medicine and Epidemiology
at the
University of Washington
THOMAS J. FAHEY, Jr., M.D.,
is the
Senior Vice President for Clinical Program Development
at
Memorial Sloan-Kettering Cancer Center in New York City
BRIAN E. HENDERSON, M.D.,
is a
Professor of Preventive Medicine
at the
Norris Comprehensive Cancer Center at the University of Southern California
ARTHUR C. MARTELLOCK, Ph.D.,
is a
consultant
in
Pittsford, New York
CHRIS D. PLATSOUCAS, M.D.,
is a
Professor of Microbiology and Immunology
at the
Temple University School of Medicine in Philadelphia
NAOMI F. ROTHFIELD, M.D.,
is a
Professor of Medicine and Rheumatic Diseases
at the
University of Connecticut School of Medicine
DIANA TAYLOR, R.N., N.P., Ph.D., F.A.A.N.,
is an
Associate Professor of Family Health Care Nursing
at the
University of California at San Francisco
RALPH C. WILLIAMS, Jr., M.D.,
is
Professor Emeritus of Medicine
at the
University of Florida
IOM Staff
ROGER HERDMAN,
Study Director
ANNICE HIRT,
Research Associate
STACEY PATMORE,
Research Associate
PATRICIA J. SPAULDING,
Project Assistant
KATHLEEN R. STRATTON,
Director,
Division of Health Promotion and Disease Prevention
DONNA D. THOMPSON,
Division Assistant
SHARON GALLOWAY,
Financial Associate
Staff Consultants
WESTLEY REEVES,
Associate Professor,
Department of Medicine, University of North Carolina at Chapel Hill
HANSPETER WITSCHI,
Professor of Toxicology,
Department of Molecular Biosciences, School of Veterinary Medicine, University of California at Davis
Drawings by Roberto Osti. Design by Anne Rogers.
OCR for page R4
Information for Women About the Safety of Silicone Breast Implants
CONTENTS
Silicone: What Is It?
3
How This Study Came About
4
What the IOM Committee Found
5
Conclusions
20
Mammograms and Other Breast Imaging in Women with Implants
21
Recommendations
24
A History of Implants
26
ABOUT THIS PUBLICATION
The Institute of Medicine report Safety of Silicone Breast Implants evaluates the evidence for associations of these devices with human health conditions, provides a comprehensive list of references, and makes recommendations for further research.
This publication, which is derived exclusively from that report, is a step toward meeting one of its recommendations—that is, making the information contained in the original report available to women who have or who are considering breast implants. In this publication, the Institute seeks to provide a short, easily understood version of that information to women.
Stuart Bondurant
Chair
Committee on the Safety of Silicone Breast Implants
Virgina L. Ernster
Vice Chair
Committee on the Safety of Silicone Breast Implants
