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The Role of Protein and Amino Acids in Sustaining and Enhancing Performance (1999)
Institute of Medicine (IOM)

Page
17
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The Role of Protein and Amino Acids in Sustaining and Enhancing Performance

I
Committee Summary and Recommendations

Part I of this report provides the Committee on Military Nutrition Research's (CMNR) overview and summary of key issues in protein metabolism, its response to specific questions posed by the Army, and the committee's conclusions and recommendations. The CMNR was requested by the U.S. Army Medical Research and Materiel Command and the Military Nutrition and Biochemistry Division of the U.S. Army Research Institute of Environmental Medicine to review the state of knowledge on protein requirements and determine if the Military Recommended Dietary Allowance (MRDA) need to be revised.

In Chapter 1, the committee presents an overview of the project using relevant background materials and the proceedings of the workshop held in March 1997 to provide a summary of key issues in determining protein requirements, various militarily relevant stressors that may influence protein requirements, and the benefits and risks of supplemental protein or individual amino acids.

The committee's response to the three questions posed by the Army, listed below, and its conclusions and recommendations are presented in Chapter 2.

  1. Do protein requirements increase with military operational stressors, including high workload with or without energy deficit? Are there gender differences in protein requirements in endurance exercise?

Page
17
Front Matter (R1-R18)
Executive Summary (1-16)
I Committee Summary and Recommendations (17-18)
1 Committee Review (19-76)
2 Responses to Questions, Conclusions, and Recommendations (77-82)
II Authored Papers and Workshop Discussions (83-84)
3 Protein and Amino Acids: Physiological Optimization for Current and Future Military Operational Scenarios (85-92)
4 Overview of Garrison, Field, and Supplemental Protein Intake by U.S. Military Personnel (93-108)
5 The Energy Costs of Protein Metabolism: Lean and Mean on Uncle Sam's Team (109-120)
6 Regulation of Muscle Mass and Function: Effects of Aging and Hormones (121-136)
7 Effects of Protein Intake on Renal Function and on the Development of Renal Disease (137-154)
8 Infection and Injury: Effects on Whole Body Protein Metabolism (155-168)
9 Inherent Difficulties in Defining Amino Acid Requirements (169-216)
10 Amino Acid Flux and Requirements: Counterpoint Tentative Estimates are Feasible and Necessary (217-242)
11 Physical Exertion, Amino Acid and Protein Metabolism, and Protein Requirements (243-254)
12 Skeletal Muscle Markers (255-278)
13 Alterations in Protein Metabolism Due to the Stress of Injury and Infection (279-284)
Discussion I (285-288)
14 Amino Acid and Protein Requirements: Cognitive Performance, Stress, and Brain Function (289-308)
15 Supplementation with Branched-Chain Amino Acids, Glutamine, and Protein Hydrolysates: Rationale for Effects on Metabolism and Performance (309-330)
16 Dietary Supplements Aimed at Enhancing Performance: Efficacy and Safety Considerations (331-340)
Discussion II (341-346)
Appendixes (347-348)
A Workshop Agenda (349-352)
B Biographical Sketches (353-368)
C Acronyms and Abbreviations (369-372)
D Proteins and Amino Acids - A Selected Bibliography (373-410)
E Protein and Energy Content of Selected Operational Rations (411-412)
Index (413-429)

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OCR for page 17
The Role of Protein and Amino Acids in Sustaining and Enhancing Performance I Committee Summary and Recommendations Part I of this report provides the Committee on Military Nutrition Research's (CMNR) overview and summary of key issues in protein metabolism, its response to specific questions posed by the Army, and the committee's conclusions and recommendations. The CMNR was requested by the U.S. Army Medical Research and Materiel Command and the Military Nutrition and Biochemistry Division of the U.S. Army Research Institute of Environmental Medicine to review the state of knowledge on protein requirements and determine if the Military Recommended Dietary Allowance (MRDA) need to be revised. In Chapter 1, the committee presents an overview of the project using relevant background materials and the proceedings of the workshop held in March 1997 to provide a summary of key issues in determining protein requirements, various militarily relevant stressors that may influence protein requirements, and the benefits and risks of supplemental protein or individual amino acids. The committee's response to the three questions posed by the Army, listed below, and its conclusions and recommendations are presented in Chapter 2. Do protein requirements increase with military operational stressors, including high workload with or without energy deficit? Are there gender differences in protein requirements in endurance exercise?

OCR for page 18
The Role of Protein and Amino Acids in Sustaining and Enhancing Performance What is the optimal protein content (and protein-energy ratio) for standard operational rations, and specifically, is the protein MRDA for operational rations (100 g/d for men and 80 g/d for women) appropriate? Is the protein MRDA for women appropriate during pregnancy and lactation? Is there evidence that supplementation with specific amino acids (AAs) or modification of dietary protein quality would optimize military performance, either cognitive or physical, during high workload, psychological stress, or energy deficit? What are the risks of amino acid supplements and high-protein diets?

Representative terms from entire chapter:

amino acids