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TABLE 2. Polymorphisms in 10 loci of P. falciparum

           

Synonymous sites analyzed

Gene

Chromosome location

Length, bp

Sequences in the sample, ni

Nonsynonymous polymorphisms, Dn

Synonymous polymorphisms, Ds

4-fold, nili

2-fold, nimi

Dhfr

4

609

32

4

0

2,144

4,128

Ts

4

1,215

10

0

0

1,250

2,640

Dhps

8

1,269

12

5

0

1,536

2,724

Mdr1

5

4,758

3

1

0

1,350

2,088

Rap1

2,349

9

8

0

1,092

1,668

Calm

14

441

7

0

0

364

602

G6pd

14

2,205

3

9

0

726

1,404

Hsp86

7

2,241

2

0

0

532

910

Tpi

597

2

0

0

180

262

CsP 5′end

3

387

25

7

0

688

2,010

Csp 3′end

3

378

25

17

0

1,050

1,625

Total

51

0

10,912

20,061

Modified from Ayala et al. (1999).



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