NASA has built a very productive relationship with the NIH based on the development and use of rotating-wall vessels. The NASA/NIH Center for Three-Dimensional Tissue Culture was started in 1994 to expose a wider community to bioreactor technology by allowing researchers from government agencies (e.g., NIH, the Food and Drug Administration, and the Department of the Navy) to test new model systems for biomedical research and basic cell and molecular biology in the rotating-wall vessel hardware with technical assistance from experienced NASA personnel. The task group believes that this outreach program is an excellent idea and recommends that a wider range of investigators be reached by opening the introductory phase of this program to extramural (nongovernment) researchers.