The EPA, FDA, and USDA should collaborate on the establishment of a database for natural plant defensive compounds of potential dietary or other toxicological concern.
Given that transfer and manipulation of genes between sexually compatible plants could potentially result in adverse effects in some cases (for example, modulation of a pathway that increases the concentration of a toxicant), and given public controversy regarding transgenic products, EPA should reconsider its categorical exemption of transgenic pest-protectants derived from sexually compatible plants.
EPA should not categorically exempt viral coat proteins from regulation under FIFRA. Rather, EPA should adopt an approach, such as the agency 's alternative proposal, that allows the agency to consider the gene transfer risks associated with the introduction of viral coat proteins to plants.
EPA should review exemptions of transgenic pest-protected plant products to ensure that they are consistent with the scientific principles elucidated in this report.