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DRI DIETARY REFERENCE INTAKES FOR Vitamin C, Vitamin E, Selenium, and Carotenoids
TABLE 6-2 Vitamin E Deficiency Symptoms in Subjects with Ataxia with Vitamin E Deficiency
Reference
Country
Subjects
Clinical Features
Burck et al., 1981
Germany
n = 1 male; aged 12
Ataxia
Sensory neuropathy
Muscle hypertrophy
Laplante et al., 1984
Canada
n = 1 male; aged 10
Areflexia
Gait and limb ataxia
Muscle weakness
Decreased vibration sense
Decreased proprioception
Limb dysmetria
Babinski sign
Harding et al., 1985
United Kingdom
n = 1 female; aged 23 (aged 13 at onset)
Head titubation
Reduced muscle tone
Ataxia
Areflexia
Romberg sign
Defective or absent vibration sense
Impaired proprioception
Krendel et al., 1987
United States
n = 1 male; aged 19
Severe dysarthria
Unintelligible speech
Bradykinesia
Absent tendon reflexes
Stumpf et al., 1987
Italy
n = 1 female; aged 30 (aged 4 at onset)
Dysarthria
Dystonic smile
Absent position sensation in leg and hands
Absent tendon reflexes
Mildly dysmetric
Extensor plantar responses
Moderately ataxic heel to shin movements
Romberg sign
Front Matter (R1-R23)
Summary (1-20)
1 Introduction to Dietary Reference Intakes (21-34)
2 Vitamin C, Vitamin E, Selenium, and •-Carotene and Other Carotenoids: Overview, Antioxidant Definition, and Relationship to Chronic Disease (35-57)
3 Vitamin C, Vitamin E, Selenium, and •-Carotene and Other Carotenoids: Methods (58-72)
4 A Model for the Development of Tolerable Upper Intake Levels for Nutrients (73-94)
5 Vitamin C (95-185)
6 Vitamin E (186-283)
7 Selenium (284-324)
8 •-Carotene and Other Carotenoids (325-382)
9 Uses of Dietary Reference Intakes (383-400)
10 A Research Agenda (401-408)
A Origin and Framework of the Development of Dietary Reference Intakes (409-412)
B Acknowledgments (413-415)
C Dietary Intake Data from the Third National Health and Nutrition Examination Survey (NHANES III), 1988–1994 (416-431)
D Dietary Intake Data from the Continuing Survey of Food Intakes by Individuals (CSFII), 1994–1996 (432-437)
E Canadian Dietary Intake Data, 1993, 1995 (438-439)
F Serum Values from the Third National Health and Nutrition Examination Survey (NHANES III), 1988–1994 (440-457)
G Options for Dealing with Uncertainties (458-462)
H Glossary and Acronyms (463-468)
I Biographical Sketches of Panel and Subcommittee Members (469-482)
Index (483-506)
