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Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids (2000)
Institute of Medicine (IOM)

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. "5 Vitamin C." Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington, DC: The National Academies Press, 2000.

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DRI DIETARY REFERENCE INTAKES FOR Vitamin C, Vitamin E, Selenium, and Carotenoids

FIGURE 5-1 Chemical structure of ascorbic acid.

volves either monooxygenase or dioxygenase activities (Levine et al., 1996b).

As a cofactor for hydroxylase and oxygenase metalloenzymes, ascorbic acid is believed to work by reducing the active metal site, resulting in reactivation of the metal-enzyme complex, or by acting as a co-substrate involved in the reduction of molecular oxygen. The

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