This report has been reviewed in draft form by individuals chosen for their diverse perspectives and technical expertise, in accordance with procedures approved by the National Research Council’s Report Review Committee. The purpose of this independent review is to provide candid and critical comments that will assist the Institute of Medicine in making the published report as sound as possible and to ensure that the report meets institutional standards for objectivity, evidence, and responsiveness to the study charge. The review comments and draft manuscript remain confidential to protect the integrity of the deliberative process. The committee wishes to thank the following individuals for their participation in the review of this report:

Donald A.Henderson, Johns Hopkins University

Richard Johnston, University of Colorado

Joyce Lashof, University of California, Berkeley

Robert Miller, (retired) National Cancer Institute

Gregory Poland, Mayo Clinic and Foundation

Hugh Tilson, University of North Carolina at Chapel Hill

Mary Wilson, Mount Auburn Hospital, Cambridge, MA

While the individuals listed above have provided constructive comments and suggestions, responsibility for the final content of this report rests solely with the authoring committee and the Institute of Medicine.

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