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1) Activity: mole for mole as active as INH

2) Orally active

3) Bactericidal

4) Active vs. nongrowing organisms (e.g., M. tuberculosis cultured under anaerobic conditions)

5) Now in initial stages of testing

Ribozyme Pharmaceuticals

0

0

0

0

Sequella Corp.

  • Ethambutol analogs (3 candidates)

Clinical testing probably

Clinical testing probably

Vaccine: Has license for new experimental vaccine (Nature 400[6741]:269; 1999)

  • Shikemic acid pathway

0

0

(inhibitor)

  • New diagnostic being studied: A patch test that may be positive in patients with active disease but not in individuals with prior infection



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