Appendix D
Biographical Information on the Committee on Developmental Toxicology

ELAINE FAUSTMAN (Chair), University of Washington, Seattle, WA. Dr. Faustman is a professor in the Department of Environmental Health and director of the Institute for Risk Analysis and Risk Communication at the University of Washington. She earned her Ph.D. in pharmacology and toxicology from Michigan State University. Her research interests include mechanistic investigations of the reproductive and developmental toxicity of metals and pesticides. She has developed quantitative risk assessment methods for noncancer end points. Dr. Faustman previously served as a member of the National Research Council Committee on Toxicology. She is an elected fellow of the American Association for the Advancement of Science.

JOHN GERHART (Vice Chair), University of California, Berkeley, CA. Dr. Gerhart is a professor in the Department of Molecular and Cell Biology at the University of California, Berkeley. He earned his PhD in biochemistry from the same institution. His research interests include the development of Xenopus and the formation and function of Spemann’s organizer. Dr. Gerhart is a member of the National Academy of Sciences.

NIGEL BROWN, St. George’s Hospital Medical School, University of London, UK. Dr. Brown is professor of developmental biology in the Department of Anatomy and Developmental Biology at St. George’s Hospital Medical School. He earned his Ph.D. in biochemistry from the University of Surrey, UK and did postdoctoral training at NIEHS. His research interests include mammalian heart development, mechanisms of teratogenesis, and left-right asymmetry. Dr. Brown is a former president of the European Teratology Society and chairman of the International Federation of Teratology Societies.



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Scientific Frontiers in Developmental Toxicology and Risk Assessment Appendix D Biographical Information on the Committee on Developmental Toxicology ELAINE FAUSTMAN (Chair), University of Washington, Seattle, WA. Dr. Faustman is a professor in the Department of Environmental Health and director of the Institute for Risk Analysis and Risk Communication at the University of Washington. She earned her Ph.D. in pharmacology and toxicology from Michigan State University. Her research interests include mechanistic investigations of the reproductive and developmental toxicity of metals and pesticides. She has developed quantitative risk assessment methods for noncancer end points. Dr. Faustman previously served as a member of the National Research Council Committee on Toxicology. She is an elected fellow of the American Association for the Advancement of Science. JOHN GERHART (Vice Chair), University of California, Berkeley, CA. Dr. Gerhart is a professor in the Department of Molecular and Cell Biology at the University of California, Berkeley. He earned his PhD in biochemistry from the same institution. His research interests include the development of Xenopus and the formation and function of Spemann’s organizer. Dr. Gerhart is a member of the National Academy of Sciences. NIGEL BROWN, St. George’s Hospital Medical School, University of London, UK. Dr. Brown is professor of developmental biology in the Department of Anatomy and Developmental Biology at St. George’s Hospital Medical School. He earned his Ph.D. in biochemistry from the University of Surrey, UK and did postdoctoral training at NIEHS. His research interests include mammalian heart development, mechanisms of teratogenesis, and left-right asymmetry. Dr. Brown is a former president of the European Teratology Society and chairman of the International Federation of Teratology Societies.

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Scientific Frontiers in Developmental Toxicology and Risk Assessment GEORGE DASTON, The Procter and Gamble Company, Cincinnati, OH. Dr. Daston is a toxicologist at Miami Valley Laboratories of the Procter and Gamble Company. He earned his Ph.D. in teratology from the University of Miami. His research interests include in vitro methodologies, teratogenic mechanisms, and risk assessment. Dr. Daston is a former member of the National Research Council Board on Environmental Studies and Toxicology. MARK FISHMAN, Massachusetts General Hospital and Harvard Medical School, Boston, MA. Dr. Fishman is chief of cardiology, director of the Cardiovascular Research Center, and chief of the Developmental Biology Laboratory at the Massachusetts General Hospital. He also is a professor of medicine at Harvard Medical School. He earned his M.D. from Harvard Medical School. Dr. Fishman’s research interests are in the development of the heart and other organ systems. He has helped pioneer the use of the zebrafish in large-scale genetic screens and has been instrumental in the discovery of many new genes critical to development of the early embryo. JOSEPH HOLSON, WIL Research Laboratories, Inc., Ashland, OH. Dr. Holson is president and director of WIL Research Laboratories, Inc. He earned his Ph.D. in physiology from University of Cincinnati College of Medicine. Dr. Holson’s scientific activities are primarily in product development and risk assessment where he specializes in developmental and reproductive toxicology. HERMAN B.W.M. KOËTER, Organisation for Economic Cooperation and Development (OECD), Paris, France. Dr. Koëter is principal administrator of the OECD Environmental Health and Safety Division. He is responsible for and directs the OECD Test Guidelines Programme, the OECD Programme on Harmonization of Classification and Labeling, the OECD Special Activity on Endocrine Disrupters, and the OECD Special Activity on Animal Welfare Policies. He is also senior adviser for OECD on human health risk characterization and assessment issues. Dr. Koëter earned his masters degree in experimental pathology and his doctoral degree in biological toxicology from Utrecht State University, Utrecht, The Netherlands. ANTHONY MAHOWALD, University of Chicago, Chicago, IL. Dr. Mahowald is Louis Block professor and chair of the Department of Molecular Genetics and Cell Biology and the Committee on Developmental Biology at the University of Chicago. He received his Ph.D. in biology from Johns Hopkins University. His research interests include the developmental genetics of oogenesis and germ-cell sex determination in Drosophila. Dr. Mahowald is a fellow of the American Academy of Arts and Sciences and a member of the National Academy of Sciences.

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Scientific Frontiers in Developmental Toxicology and Risk Assessment JEANNE MANSON, University of Pennsylvania, Philadelphia, PA. Dr. Manson is a fellow in the Center for Clinical Epidemiology and Biostatistics at the University of Pennsylvania, where she is obtaining her M.S. in clinical epidemiology. She earned her Ph.D. in developmental biology from Ohio State University. Dr. Manson previously worked in the pharmaceutical industry in the area of reproductive toxicology. RICHARD MILLER, University of Rochester, Rochester, NY. Dr. Miller is professor and associate chair of obstetrics and gynecology, and professor of environmental medicine at the University of Rochester School of Medicine and Dentistry. He is also director of the Division of Research and Director of the PEDECS, which is a regional and national Teratogen Information Service. He earned his Ph.D. in pharmacology and toxicology from Dartmouth Medical School. Dr. Miller’s research interests include the vertical transmission of the HIV-1 and the role of anti-HIV therapy, the toxicity of heavy metals, and the role of vitamins in normal and abnormal development. PHILIP MIRKES, University of Washington, Seattle, WA. Dr. Mirkes is research professor in the Department of Pediatrics at the University of Washington. He earned his Ph.D. in zoology from the University of Michigan. Dr. Mirkes’ research interests include teratology and developmental toxicology, heat shock response, and apoptosis. DANIEL NEBERT, University of Cincinnati Medical Center, Cincinnati, OH. Dr. Nebert is a professor in the Department of Environmental Health at the University of Cincinnati Medical Center and in the Department of Pediatrics, Division of Human Genetics at Children’s Hospital Medical Center. He earned his M.S. in biochemistry and M.D. from the University of Oregon Medical School. He is author or coauthor of more than 460 publications in the fields of pharmacogenetic disorders, toxicology, gene expression and signal transduction pathways, gene nomenclature and evolution, teratology, and developmental biology. DREW NODEN, Cornell University, Ithaca, NY. Dr. Noden is professor of embryology in the Department of Biomedical Sciences of the College of Veterinary Medicine at Cornell University. He earned his Ph.D. in zoology from Washington University. Dr. Noden’s research focuses on vertebrate craniofacial development, with particular emphasis on the migratory patterns of mesenchymal cells and the factors that influence their assembly into muscle, endothelial, and connective tissues. VIRGINIA PAPAIOANNOU, Columbia University, NY. Dr. Papaioannou is professor of genetics and development at the College of Physicians and Sur-

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Scientific Frontiers in Developmental Toxicology and Risk Assessment geons of Columbia University. She earned her Ph.D. in genetics from the University of Cambridge, England. Her research interests include implantation, embryonic cell lineages and the genetics of early embryonic development, using mutations and transgenic technology. GARY SCHOENWOLF, University of Utah, Salt Lake City, UT. Dr. Schoenwolf is professor of neurobiology and anatomy, and member of the Huntsman Cancer Institute at the University of Utah School of Medicine. He earned his M.S. and Ph.D. in zoology from the University of Illinois, Champaign-Urbana. His research interests include gastrulation, neurulation, and neuraxial patterning. FRANK WELSCH, Chemical Industry Institute of Toxicology (CIIT), Research Triangle Park, NC. Dr. Welsch is senior scientist and head of the Teratology Laboratory at CIIT. He earned his qualification as a veterinarian and doctor medicinae veterinariae degree from the Veterinary School of Freie Universität, Berlin, Germany. His research interests include development of new testing methods to predict developmental toxicity hazards. WILLIAM B. WOOD, University of Colorado, Boulder, CO. Dr. Wood is a professor in the Department of Molecular, Cellular and Developmental Biology at the University of Colorado, Boulder, and a member of the Cancer Institute, University of Colorado Health Sciences Center, Denver. He earned his Ph.D. in biochemistry from Stanford University. He studies the developmental genetics and molecular biology of embryonic pattern formation and sex determination in the nematode Caenorhabditis elegans. Dr. Wood is a fellow of the American Academy of Arts and Sciences and a member of the National Academy of Sciences.