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Toxicological Effects of Methylmercury
microgliocytosis and cerebellar degeneration
Mouse
24 wk
1.9
Paralysis
MacDonald and Harbison 1977
Mouse (C57B1/6)
17 d
6 d
4
8
Increased auditory brainstem response thresholds
Wassick and Yonovitz 1985
Mouse (B6C3F1 ) 2 yr
2 yr
0.6
Paralysis, neuropathy
Mitsumori et al. 1990
Rabbit (New Zealand)
7 d
30
Ataxia, decreased muscle tone, reduced splay reflex
Jacobs et al. 1977
Cat
0.05
Ataxia
Khera et al. 1974
Cat
60 wk
0.046
Impaired hopping
Charbonneau et al. 1976
Abbreviations: NOAEL, no-observed-adverse-effect level; LOAEL, lowest-observed-adverse-effect level; NS, not stated.
