TABLE 7-1 Estimates of Standardized Regression Coefficients Based on Reported Study Results

Study

Exposure SD

Outcome

Outcome SD

Raw Regression Coefficient

Standardized Regression Coefficient

Faroe Islanda

0.375

Finger Tapping

6.15

−1.1

−0.07 Islands a

   

CPT-Errors b

0.54

0.12

0.08

   

CPT-Reaction

80

40.3

0.18

   

Time

     
   

Digit Span

1.5

−.27

−0.06

   

Boston Naming

5.3

−1.77

−0.12

   

Test-no cues

     
   

Boston Naming

5.3

−1.91

−0.13

   

Test-cues

     
   

CVLT-Short-term

3.1

−0.57

−0.06

   

CVLT-Long-term

3.8

−0.55

−0.05

New Zealandc

3.31

TOLD-Language Development

16

−0.6

−0.12

   

WISC-R:PIQ

16

−0.54

−0.11

   

WISC-R:FSIQ

16

−0.55

−0.11

   

McCarthy

10

−0.53

−0.17

   

Perceptual

     
   

Performance

     
   

McCarthy Motor

0.15

−0.007

−0.15

   

Test b

     

aExposures measured on the log-scale. Exposure SD and regression coefficients provided by study investigators (Grandjean et al. 1997). Outcome SDs estimated by dividing the interquartile range by 1.3.

bLog transformed.

cData from Crump et al. 1998.

Abbreviations: CPT, Continuous Performance Test; CVLT, California Verbal Learning Test; TOLD, Test of Language Development; WISC-R:PIQ, Wechsler Intelligence Scale for Children-Revised Performance IQ; WISC-R:FSIQ, Wechsler Intelligence Scale for Children-Revised Full-Scale IQ.

response estimates for the Faroe Islands study were also sensitive to omission of some of the observations with very high exposure levels.



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