Toxicological Effects of Methylmercury

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Toxicological Effects of Methylmercury (2000)
Commission on Life Sciences (CLS)

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. "Risk Characterization and Public Health Implications." Toxicological Effects of Methylmercury. Washington, DC: The National Academies Press, 2000.

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Toxicological Effects of Methylmercury

The BMDL of 12 ppm is nearly identical to the BMDL currently used by EPA (11 ppm). Given the toxicokinetic variability and uncertainties in the data, an uncertainty factor of at least 10 is supported by the committee. Therefore, on the basis of its analysis of the available data, the committee finds that the value of EPA's current RfD for MeHg (0.1 µg/kg per day) is scientifically justifiable for the protection of public health.

REFERENCES

Bakir, F., S.F. Damluji, L. Amin-Zaki, M. Murtadha, A. Khalidi, N.Y. al-Rawi, S. Tikriti, H.I. Dhahir, T.W. Clarkson, J.C. Smith, and R.A. Doherty. 1973. Methylmercury poisoning in Iraq. Science 181(96):230-241.

Budtz-Jørgensen, E., N. Keiding, and P. Grandjean. 1999. Benchmark Modeling of the Faroese Methylmercury Data. Research Report 99/5. Prepared at the University of Copenhagen, Denmark, for the U.S. Environmental Protection Agency.

Burbacher T.M., M.K. Mohamed, and N.K. Mottett. 1988. Methylmercury effects on reproduction and offspring size at birth . Reprod. Toxicol 1(4):267-278.

Crump, K.S. 1984. A new method for determining allowable daily intakes. Fundam. Appl. Toxicol. 4(5):854-871.

Crump, K.S., T. Kjellström, A.M. Shipp, A. Silvers, and A. Stewart. 1998. Influence of prenatal mercury exposure upon scholastic and psychological test performance: benchmark analysis of a New Zealand cohort. Risk Anal. 18(6):701-713.

Crump, K.S., C. Van Landingham, C. Shamlaye, C. Cox, P.W. Davidson, G.J. Myers, and T.W. Clarkson. 2000. Benchmark concentrations for methylmercury obtained from the Seychelles child development study. Environ. Health Perspect. 108(3):257-63.

Crump K, J. Viren, A. Silvers, H. Clewell 3rd, J. Gearhart, and A. Shipp. 1995. Reanalysis of dose-response data from the Iraqi methylmercury poisoning episode. Risk Anal. 15(4):523-532.

Dantas, D.C., and M.L. Queiroz. 1997. Immunoglobulin E and autoantibodies in mercury-exposed workers. Immunopharmacol. Immunotoxicol. 19(3): 383-92.

Davidson, P.W., G.J. Myers, C. Cox, C. Shamlaye, O. Choisy, J. Sloane-Reeves, E. Cernchiari, D.O. Marsh, M. Berlin, M. Tanner, and T.W. Clarkson. 1995a. Neurodevelopmental test selection, administration, and performance in the main Seychelles child development study. Neurotoxicology 16(4):665-676.