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A Healthy NIH Intramural Program: Structural Change or Administrative Remedies? Report of a Study (1988)
Institute of Medicine (IOM)

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A Healthy NIH Intramural Program: Structural Change or Administrative Remedies?

A Healthy NIH Intramural Program

Structural Change or Administrative Remedies?

Report of a Study by a Committee of the Institute of Medicine

Division of Health Sciences Policy

National Academy Press

Washington D.C.

1988

Page
I

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A Healthy NIH Intramural Program: Structural Change or Administrative Remedies? A Healthy NIH Intramural Program Structural Change or Administrative Remedies? Report of a Study by a Committee of the Institute of Medicine Division of Health Sciences Policy National Academy Press Washington D.C. 1988

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A Healthy NIH Intramural Program: Structural Change or Administrative Remedies? NOTICE: The project that is the subject of this report was approved by the Governing Board of the National Research Council, whose members are drawn from the councils of the National Academy of Sciences, the National Academy of Engineering, and the Institute of Medicine. The members of the committee responsible for the report were chosen for their special competencies and with regard for appropriate balance. This report has been reviewed by a group other than the authors according to procedures approved by a Report Review Committee consisting of members of the National Academy of Sciences, the National Academy of Engineering, and the Institute of Medicine. The Institute of Medicine was chartered in 1970 by the National Academy of Sciences to enlist distinguished members of the appropriate professions in the examination of policy matters pertaining to the health of the public. In this, the Institute acts under both the Academy’s 1863 congressional charter responsibility to be an advisor to the federal government and its own initiative in identifying issues of medical care, research, and education. This project (Evaluation Project No. NIH 88–310 for Contract Number NO1-OD-8-2104) received support from the evaluation set-aside Section 513, Public Health Service Act. 2101 Constitution Avenue, N.W. Washington, D.C. 20418 (202) 334-3300 IOM 88-08

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A Healthy NIH Intramural Program: Structural Change or Administrative Remedies? INSTITUTE OF MEDICINE COMMITTEE TO STUDY STRATEGIES TO STRENGTHEN THE SCIENTIFIC EXCELLENCE OF THE NATIONAL INSTITUTES OF HEALTH INTRAMURAL RESEARCH PROGRAM HAROLD T.SHAPIRO, (Chairman), President, Princeton University, Princeton, New Jersey. MICHAEL S.BROWN,* Professor of Genetics, University of Texas Health Science Center, Dallas, Texas. JOHN T.DUNLOP,* Lamont University Professor, Emeritus, Harvard University, Cambridge, Massachusetts. GERALD D.FISCHBACH, Chairman of Anatomy and Neurobiology, Washington University, St. Louis, Missouri. MARIAN E.KOSHLAND, Professor and Chair, Department of Microbiology and Immunology, University of California, Berkeley, California. CHARLOTTE V.KUH, Executive Director, Educational Testing Service, Princeton, New Jersey. ROBERT I.LEVY,* President and Chief Executive Officer, Sandoz Research Institute, East Hanover, New Jersey. WALTER E.MASSEY, Vice President for Research and for Argonne National Laboratory, The University of Chicago, Chicago, Illinois. ROBERT G.PETERSDORF,* President, Association of American Medical Colleges, Washington, D.C. PAUL GRANT ROGERS,* Partner, Hogan & Hartson, Washington, D.C. BENNO C.SCHMIDT,* Managing Partner, J.H.Whitney & Company, New York, New York. LLOYD H.SMITH,* Associate Dean and Professor of Medicine, University of California at San Francisco, San Francisco, California. ELMER B.STAATS, Former U.S. Comptroller General, Washington, D.C. P.ROY VAGELOS,* Chairman and Chief Executive Officer, Merck and Company, Rahway, New Jersey. * Member, Institute of Medicine

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A Healthy NIH Intramural Program: Structural Change or Administrative Remedies? STUDY STAFF RUTH ELLEN BULGER, Director, Division of Health Sciences Policy MICHAEL L.MILIMAN, Study Director JESSICA TOWNSEND, Associate Study Director CARLOTTA C.MOLITOR, Research Associate WALLACE K.WATERFALL, Editor, Institute of Medicine CONSULTANTS ALAN L.DEAN MICHAEL FINN HELEN HOFER GEE HAROLD SEIEMAN ROBERT A.WALKINGTON

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A Healthy NIH Intramural Program: Structural Change or Administrative Remedies? CONTENTS     SUMMARY   1     INTRODUCTION   11      The Charge to the Committee   11      The Committee’s Interpretation of Their Charge   11      Scope of the Study   12      Conduct of the Study   13      Origins of the Study   13      Structure and Funding of NIH and Its Intramural Program   16 CHAPTER 1.   MISSION AND PURPOSES OF THE NIH INTRAMURAL PROGRAM   23      Role as a Government Laboratory   24      The Environment   24      Research Training   25      Basic and Clinical Research   26      The Application and Communication of Research   27      Long-Term Research   28      The Intramural Program in Relation to the Extramural Program   28      Conclusion   29 CHAPTER 2.   SCIENTIFIC EXCELLENCE OF NIH INTRAMURAL PROGRAM   33      Important Discoveries by Scientists in the NIH Intramural Program   33      Bibliometric Analysis of Publications in Scientific Journals   35      Peer Judgment of Scientific Contribution   38      New Young Talent   39      Administrative Measures to Strengthen the Current Program   40      Conclusion   44

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A Healthy NIH Intramural Program: Structural Change or Administrative Remedies? CHAPTER 3.   SIZING UP ADMINISTRATIVE PROBLEMS   47      Personnel   48      Compensation   49      Beginning Researchers   50      Mid-Level Researchers   53      Senior Researchers   59      Support Staff   63      Summary of Compensation Findings   64      The Personnel System   65      Barriers to a Productive Work Environment   68      Coping with a Changing Environment   72      Summary of Administrative Problems   73      Endnotes   75      Tables   83 CHAPTER 4.   SOLVING ADMINISTRATTVE PROBLEMS   119      The Policy Background   120      Models for Organizational Reform   121      Addressing Problems that Exist under the Present Organization   126      Improving the NIH Managerial Environment   133      Conclusions and Recommendations   134     APPENDIXES     A   ORGANIZATIONS AND INDIVIDUALS PROVIDING TESTIMONY REGARDING THE NIH INTRAMURAL PROGRAM   143 B   NIH VISIT ON MAY 25, 1988   146 C   SUMMARY OF ACHIEVEMENTS OF NIH INTRAMURAL PROGRAMS   148 D   BIBLIOMETRIC ANALYSIS   156

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A Healthy NIH Intramural Program: Structural Change or Administrative Remedies? FIGURES Figure I-1   NIH Organizational Chart   17 Figure 3-1   U.S. and Foreign Fellows, 1983 and 1988   51 Figure 3-2   Attrition Rates 1983–1987 for Tenured M.D.s and Ph.D.s   55 Figure 3-3   Salaries for M.D.s and Ph.D.s, 1987, NIH vs Academic Centers,   60 Figure 4-1   NBS Personnel Management Demonstration Project   128 TABLES Table I-1   NIH Obligations by Institute 1977–1987   21 Table 2-1   Percent Papers Among Most Highly Cited 10 Percent   37 Table 2-2   Ratio Intramural to Academic Average Citations Per Paper   37 Table 3-1a   Personnel Systems Under Which NIH Tenured Scientists Are Employed   83 Table 3-1b   Salary Rates for Permanent NIH Scientists Under the General Schedule and Senior Executive Service   86 Table 3-2   NIH Fellows by Title and Degree as of End of Fiscal Years 1983–1988   87 Table 3-3   Non-Tenured Intramural Employment   88 Table 3-4   Time Line for Trainees at NIH   90 Table 3-5   NIH Medical Staff Fellowship Program Statistics, 1977–1988   91 Table 3-6a   Rates of Conversion of NIH Staff Fellows to Permanent GS and CO Appointments   92 Table 3-6b   Conversions of NIH Fellows to Full-Time Permanent Appointments in General Schedule (GS/GM), Commissioned Corps (CO) Positions. Fiscal Years 1983–1987   93 Table 3-7   Grades Within Senior Investigator Category   94

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A Healthy NIH Intramural Program: Structural Change or Administrative Remedies? Table 3-8   Selected Employment Data for Current Full-Time Permanent NIH Tenured Scientists in Intramural Positions by Grade, 1983–1988   95 Table 3-9   Selected Employment Data for Full-Time Permanent NIH Tenured Scientists Who Left NIH Intramural Positions by Grade, Fiscal Years 1983–1987   101 Table 3-10   Attrition of NIH Full-Time Permanent Tenured Scientists (M.D.s and Ph.D.s) in Intramural Positions by Grade, Fiscal Years 1983–1987   106 Table 3-11   Appointments of Scientists to NIH Intramural Positions by Grade and Degree. Fiscal Years 1983–1987   111 Table 3-12   Appointment of Scientists to NIH Intramural Programs. Distribution by Grade. 1983–1987   112 Table 3-13   Comparative Salaries of Research Scientists   113 Table 3-14   Change in Average Annual Salaries Reported by Doctorates at NIH in 1981 by Type of Employer in 1987   114 Table 3-15   Comparison of Physician Compensation: NIH and American Medical Schools   115 Table 3-16   Comparison of Ph.D. Pay: NIH and American Medical Schools   116 Table 3-17   Allied Health Specialists Salary Comparison—Washington, D.C. Area. January 1988   117

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A Healthy NIH Intramural Program: Structural Change or Administrative Remedies? ACKNOWLEDGEMENTS The committee appreciates the cooperation and assistance it received from many individuals and organizations. Space prevents acknowledging them all, although every input contributed to the overall report. A few warrant special mention. More than 50 organizations and individuals (Appendix A) provided testimony to the committee regarding the NIH Intramural Program within a very brief timeframe; we offer them each our thanks. The National Institutes of Health responded to our many requests for data. We would like to thank Philip S.Chen, Associate Director for Intramural Affairs; Richard G.Wyatt, Special Assistant for Intramural Affairs; Kurt Habel, Chief, Program Planning Branch; John D.Mahoney, Associate Director for Administration; Norman D.Mansfield; Director, Division of Financial Management; and Robert T.Dillon, Chief, Staffing Management Branch, Division of Personnel Management, and his staff. Our thanks extend to the other NIH staff who generously provided insights for the committee, and especially to Sean Donohue, Office of Science Policy and Legislation, Program Planning Branch, who, by facilitating our many requests, smoothed project progress. Bradie Methany, Coordinator of the Delegation for Basic Biomedical Research, offered direction leading to staff interviews with private biomedical research laboratories, while Susan Racca, Director of Special Projects, Industrial Biotechnology Association, provided yet other insights into this sector. Representatives of a number of the nation’s most prestigious postdoctoral fellowships gave generously of their time for interviews: The American Cancer Society, Damon Runyon-Walter Winchell Cancer, Helen Hay Whitney, Jane Coffin Childs, Leukemia Society of America, Markey Charitable Trust, and the Pharmaceutical Manufacturers Association Foundation, Inc. A very special acknowledgement must go to Jean M.Haddock, Manager, American Society for Clinical Investigation (ASCI), who through a major effort made possible a survey of the more than 2,000 ASCI members, to which its membership responded overwhelmingly. Lynn Morrison, Director for Public Policy, American Federation for Clinical Research, provided the committee with additional perspectives.

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A Healthy NIH Intramural Program: Structural Change or Administrative Remedies? Paul Jolly, Associate Vice President for Operational Studies, Association of American Medical Colleges, provided valuable data. Mark Abramson, Executive Director, Center for Excellence in Government, offered his observations. Among the staff of government agencies who shared their experiences with the IOM staff and committee, we wish to recognize Harold J.Reese, Chief, Labor Management Relations and Staff Services, National Bureau of Standards (presently the National Institute of Standards and Technology) ; Kenneth E.Kinnamon, Uniformed Services University of the Health Sciences; Charles Levine, Deputy Director of the National Commission on the Public Service; William M.Tolles, Associate Director of Research, Strategic Planning, Naval Research Laboratory, Washington, D.C.; and Sheldon B. Clark, Ph.D., Senior Research Scientist, Labor and Policy Studies Program; Manpower, Education, Research, and Training Division, Oak Ridge Associated Universities. Harold T.Shapiro Chairman Committee to Study Strategies to Strengthen the Scientific Excellence of the NIH Intramural Research Program