TABLE E.1 Human Studies of Organophosphate (OP) Pesticide Poisonings

Reference

Population

 

Exposed

Control

Health Outcomes

Exposure

Adjustment

Results

Rosenstock et al., 1991

35 hospitalized for OP poisoning

25 no prior OP poisoning

NP battery, psychiatric exam 1–3 years after hospitalization

OP poisoned or not

Matching: age

NP and psychological symptoms poorer in exposed group

 

Population based; Leon, Nicaragua

 

Reidy and Bowler, 1992

21 field workers with documented acute toxicity

11 cannery workers

NP battery; symptoms questionnaire

Acute toxicity or not

Matching: age, sex, education, SES

NP poorer for acute toxicity group

Steenland et al., 1994

128 men; OP poisoning

90 male friends of exposed; no poisoning

Neurological tests; NP battery; Neurological exam 1–9 years after poisoning

OP poisoned or not

Regression: age, race, body mass index, language, alcohol, sleep, smoking, coffee, medications, current exposure

Trend only for NP poorer in exposed group

 

California registry—same as Ames, 1995



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