TABLE E.2 Studies on Persons Not Previously Poisoned by Organophosphate (OP) Pesticides

Reference

Population

 

Exposed

Controls

Health Outcomes

Exposure

Adjustment

Results

Daniell et al., 1992

49 male pesticide applicators in orchards

40 slaughterhouse workers

Pre–Post NP battery

Pre–post measures over few months; applicator vs. control; cholinesterase levels

Preseason NP performance

Controlling for baseline NP performance, only symbol digit was worse in postseason for applicators

 

Washington State

Ciesielski et al., 1994

202 farmworkers

42 nonfarmworkers

Self-reported symptoms over prior week

Self-reported pesticide exposure over prior month; erythrocyte cholinesterase levels

None

Only odds of diarrhea higher for subjects with low AChE; odds of many symptoms higher among persons with higher self-reported exposures including dysgeusia

 

Two community health centers in North Carolina

Stephens et al., 1995

146 sheep farmers or dippers, no dipping in prior 2 months

143 quarry workers

NP battery, psychiatric symptoms (GHQ)

Sheep farmer vs. control; lifetime exposure by questionnaire

Regression: age, education, alcohol, comp. experience, language, time of day, smoking, accuracy

Sheep farmers worse on sustained attention and processing speed; greater vulnerability to psychiatric disorder on GHQ

 

British Wool Marketing Board



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