Choline: The AI is based on a single experiment in adult men. Choline 's potential role in reducing chronic disease risk was considered in developing its AI.
Biotin: For infants exclusively fed human milk, the AI is based on the biotin content of human milk. This level is extrapolated for all other age groups.
Pantothenic acid: The AI is based on estimated mean intakes of apparently healthy populations.
In general, how does the Adequate Intake (AI) compare with the Estimated Average Requirement (EAR) and the Recommended Dietary Allowance (RDA)?
The amount of evidence suitable for setting the AI is less than that available for setting the EAR and deriving the RDA. When the AI represents a suitable group mean intake, by definition, it is above the (unknown) EAR and generally should be above the (unknown) RDA.
Like the RDAs (which are derived from the EARs), the AIs are levels of nutrient intake that should be associated with a low risk of developing a condition related to a nutrient deficiency or some other negative functional outcome (see Appendix F for details). Intakes at the level of the RDA or AI would not necessarily replete or rehabilitate individuals previously undernourished, nor would they be adequate for persons afflicted by a disease that increased requirements.
Can the Adequate Intake (AI) be used to determine the prevalence of inadequate nutrient intakes in a group?