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Support for this project was provided by the Department of the Army (contract no. DAMD17-95-5028). The views, opinions, and/or findings contained in this report are those of the Committee to Study the Interactions of Drugs, Biologics, and Chemicals in U.S. Military Forces and should not be construed as an official Department of the Army position, policy or decision unless so designated by other documentation.
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COMMITTEE TO STUDY THE INTERACTIONS OF DRUGS, BIOLOGICS, AND CHEMICALS IN U.S. MILITARY FORCES
ROBERT G. PETERSDORF, Chair, Distinguished Professor of Medicine,
University of Washington, Puget Sound Health Care System, Seattle
DONNA DAY BAIRD, Epidemiologist,
Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina
WALTER H. CARTER, Chair,
Department of Biostatistics, Virginia Commonwealth University/Medical College of Virginia
JOY A. CAVAGNARO, Senior Pharmacologist,
Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland
JOHN DOULL, Professor,
Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City
MARY CAROLYN HARDEGREE, Director,
Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland
DAVID KORN, Professor of Pathology,
Stanford University School of Medicine and Distinguished Scholar in Residence, Association of American Medical Colleges, Washington, D.C.
GENEVIEVE M. MATANOSKI, Professor of Epidemiology,
School of Hygiene and Public Health, Johns Hopkins University
PHILIP K. RUSSELL, Professor of International Health,
School of Hygiene and Public Health, Johns Hopkins University
JAY P. SANFORD, Professor of Internal Medicine,
University of Texas Southwestern Medical Center, and Dean Emeritus, Uniformed Services University of the Health Sciences, Bethesda, Maryland
ANDY STERGACHIS, Chair,
Department of Pharmacy, School of Pharmacy, University of Washington
STEPHEN I. WASSERMAN, Chair,
Department of Medicine, University of California at San Diego Medical Center
RAYMOND S. H. YANG, Director,
Center for Environmental Toxicology and Technology, Colorado State University
Study Staff
RICHARD N. MILLER, Director,
Medical Follow-up Agency
WILLIAM F. PAGE, Study Director
CAROL A. MACZKA, Senior Program Officer
ERIN M. BELL, Research Associate
PAMELA C. RAMEY-McCRAY, Project Assistant
Preface
At the request of the Department of the Army, the Medical Follow-up Agency of the Institute of Medicine established a committee to review the available medical and scientific information on the interactions of drugs, biologics, and chemicals. The committee was asked to consider this topic further, specifically regarding U.S. military personnel, who are exposed to numerous drugs, biologics, and vaccines throughout their basic training and prior to and during deployment.
The committee met in Washington, D.C., on four separate occasions: September 5–6, 1995, and March 5–6, May 1–2, and June 18, 1996. During the first two meetings the committee heard testimony from officials of the U.S. Army, the Food and Drug Administration, the Centers for Disease Control and Prevention, and the British Ministry of Defence. This report sets forth the results of the committee's deliberations.
The committee is deeply appreciative of the testimony and written material submitted by the various agencies and of the work of the Medical Follow-up Agency. In particular, the committee thanks Richard Miller, William Page, Carol Maczka, Erin Bell, Pamela Ramey-McCray, and Nancy Diener for staff support. The committee also thanks Michael Hayes and Michael Edington for editorial review.
Robert G. Petersdorf, Chair