Suggested Citation:"Appendix B: Computation of Average Daily Dose." National Research Council. 2012. Water Reuse: Potential for Expanding the Nation's Water Supply Through Reuse of Municipal Wastewater. Washington, DC: The National Academies Press. doi: 10.17226/13303.
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Computation of Average Daily Dose
The Average Daily Dose from all exposures to reclaimed water (ADDRW) can be estimated using the following equation (modified from Hutcheson et al., 1990):
ADDRW = ADDR + ADDD + ADDI
The Average Daily Dose from ingestion of the reclaimed water (ADDR) can be estimated using the following equation (modified from Hutcheson and Martin, 1992):
where
| ContaminantR | = Concentration of chemical in reclaimed water (mass/volume), | |
| VI | = Daily volume of reclaimed water ingestion (mass/volume), | |
| BAF | = Bioavailability adjustment factor, | |
| D2 | = Duration of the exposure period (time), | |
| BW | = Average body weight (e.g., 70 kg), | |
| AP | = Averaging period (time), | |
| C | = Appropriate units conversion factor. |
The Average Daily Dose from dermal contact with reclaimed water (ADDD) can be estimated using the following equation:
where
| ContaminantR | = Concentration of chemical in reclaimed water (mass/volume), | |
| SA | = Skin surface area in contact with the surface water during the period of exposure (area), | |
| PC | = Permeability constant (volume/time × area), | |
| D1 | = Average duration of each exposure event (time/event), | |
| D2 | = Duration of the exposure period (time), | |
| BAF | = Bioavailability adjustment factor, | |
| F | = Number of exposure events during the exposure period divided by the number of days in the exposure period (events/time), | |
| D1 | = Average duration of each exposure event (time/event), | |
| D2 | = Duration of the exposure period (time), | |
| BW | = Average body weight (e.g., 70 kg), | |
| AP | = Averaging period (time), | |
| C | = Appropriate units conversion factor. |
Suggested Citation:"Appendix B: Computation of Average Daily Dose." National Research Council. 2012. Water Reuse: Potential for Expanding the Nation's Water Supply Through Reuse of Municipal Wastewater. Washington, DC: The National Academies Press. doi: 10.17226/13303.
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The Average Daily Dose from inhalation of contaminants in reclaimed water (ADDI) can be estimated using the following equation:
where
| ContaminantR | = Concentration of chemical in reclaimed water (mass/volume), | |
| VR | = Daily respiratory volume during the period of exposure (volume/time), | |
| BAF | = Bioavailability adjustment factor, | |
| F | = Number of exposure events during the exposure period divided by the number of days in the exposure period (events/time), | |
| D1 | = Average duration of each exposure event (time/event), | |
| D2 | = Duration of the exposure period (time), | |
| BW | = Average body weight (e.g., 70 kg), | |
| AP | = Averaging period (time), | |
| C | = Appropriate units conversion factor. |
