Skip to main content

Self-Perpetuating Structural States in Biology, Disease, and Genetics

View Cover

Overview

Contributors

Topics

Suggested Citation

National Academy of Sciences. 2002. Self-Perpetuating Structural States in Biology, Disease, and Genetics. Washington, DC: The National Academies Press. https://doi.org/10.17226/10620.

Import this citation to:

Publication Info

140 pages | 8.5 x 11
DOI: https://doi.org/10.17226/10620
Contents

Table of Contents

skim chapter
Front Matter i-vi
Self-perpetuating structural states in biology, disease, and genetics 1-1
Transmission of prions 2-7
Conservation of a portion of the S. cerevisiae Ure2p prion domain that interacts with the full-length protein 8-15
Interactions among prions and prion “strains” in yeast 16-23
Identification of benzothiazoles as potential polyglutamine aggregation inhibitors of Huntington 24-30
Chaperoning brain degeneration 31-35
Molecular chaperones as modulators of polyglutamine protein aggregation and toxicity 36-42
Studies of the aggregation of mutant proteins in vitro provide insights into the genetics of amyloid diseases 43-50
Sequence-dependent denaturation energetics: A major determinant in amyloid disease diversity 51-56
The insulation of genes from external enhancers and silencing chromatin 57-61
Histone H3 lysine 4 methylation is mediated by Set1 and promotes maintenance of active chromatin states in fission yeast 62-69
Changes in the middle region of Sup35 profoundly alter the nature of epigenetic inheritance for the yeast prion [PSI+] 70-77
Heritable chromatin structure: Mapping “memory” in histones H3 and H4 78-85
Does heterochromatin protein 1 always follow code? 86-93
Self-perpetuating epigenetic pili switches in bacteria 94-100
Histone H3 variants specify modes of chromatin assembly 101-108
Induction and maintenance of nonsymmetrical DNA methylation in Neurospora 109-114
Locus-specific control of asymmetric and CpNpG methylation by the DRM and CMT3 methyltransferase genes 115-122
RNA-directed DNA methylation in Arabidopsis 123-134
Resources
Rights

Copyright Information

The National Academies Press and the Transportation Research Board have partnered with Copyright Clearance Center to offer a variety of options for reusing our content. You may request permission to:

  • Republish or display in another publication, presentation, or other media
  • Use in print or electronic course materials and dissertations
  • Share electronically via secure intranet or extranet
  • And more

For most Academic and Educational uses no royalties will be charged although you are required to obtain a license and comply with the license terms and conditions.

Click here to obtain permission for Self-Perpetuating Structural States in Biology, Disease, and Genetics.

Translation and Other Rights

For information on how to request permission to translate our work and for any other rights related query please click here.

Copyright.com Customer Service

For questions about using the Copyright.com service, please contact:

Copyright Clearance Center
22 Rosewood Drive
Danvers, MA 01923
Tel (toll free): 855/239-3415 (select option 1)
E-mail: info@copyright.com
Web: https://www.copyright.com
Stats

Loading stats for Self-Perpetuating Structural States in Biology, Disease, and Genetics...