There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised?
Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.
National Research Council. 1988. Mapping and Sequencing the Human Genome. Washington, DC: The National Academies Press. https://doi.org/10.17226/1097.
Chapters | skim | |
---|---|---|
Front Matter | i-xii | |
1 Executive Summary | 1-11 | |
2 Introduction | 12-25 | |
3 Implications for Medicine and Science | 26-33 | |
4 Mapping | 34-55 | |
5 Sequencing | 56-74 | |
6 The Collection, Analysis, and Distribution of Information and Materials | 75-85 | |
7 Implementation and Management Strategies | 86-98 | |
8 Implications for Society | 99-104 | |
Appendix A Glossary | 105-107 | |
Appendix B Curricula Vitae of Committee Members | 108-110 | |
Appendix C Invited Speakers at Committee Meetings | 111-112 | |
Index | 113-116 |
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