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Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals (2001)

Chapter: C Glossary of Acronyms, Abbreviations, and Symbols

« Previous: B Diagram of the AEGL Development Process
Suggested Citation:"C Glossary of Acronyms, Abbreviations, and Symbols." National Research Council. 2001. Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals. Washington, DC: The National Academies Press. doi: 10.17226/10122.
×

Appendix C
Glossary of Acronyms, Abbreviations, and Symbols


AAPCC

American Association of Poison Control Centers

ACGIH

American Conference of Governmental Industrial Hygienist

ACOEM

American College of Occupational and Environmental Medicine

ADI

acceptable daily intake.

AEGL

acute exposure guidelines levels

AFL-CIO

American Federation of Labor-Congress of Industrial Organizations

AIHA

American Industrial Hygienist Association

ATSDR

Agency for Toxic Substances and Disease Registry (U.S.)


BMC

benchmark concentration

BMC05

benchmark concentration, 5% response

BMC10

benchmark concentration, 10% response


CAAA

Clean Air Act Amendments (U.S. EPA)

CAER

Community Awareness and Emergency Response

CMA

Chemical Manufacturers Association, now known as the American Chemistry Council

CAS

Chemical Abstract Service (U.S.)

CDC

Centers for Disease Control and Prevention (U.S. DHHS)

CEEL

community emergency exposure levels (U.S. NRC)

Suggested Citation:"C Glossary of Acronyms, Abbreviations, and Symbols." National Research Council. 2001. Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals. Washington, DC: The National Academies Press. doi: 10.17226/10122.
×

CEL

continuous exposure limits (U.S. NRC)

COT

Committee on Toxicology (U.S. NRC)

C×t

concentration×time

CURE

Chemical Unit Record Estimate database


DFO

designated federal officer

DOD

Department of Defense (U.S.)

DOE

Department of Energy (U.S.)

DOT

Department of Transportation (U.S.)

DTIC

Defense Technical Information Center (U.S.)


ECETOC

European Chemical Industry Ecology and Toxicology Centre

EEGL

emergency exposure guidance levels (U.S. NRC)

EEL

emergency exposure limits (U.S. NRC)

einsatz-toleranzwert

[action tolerance levels] (Federation for the Advancement of German Fire Prevention)

EPA

Environmental Protection Agency (U.S.)

ERP

emergency response planning (AIHA)

ERPG

emergency response and planning guidelines (AIHA)


FACA

Federal Advisory Committee Act (U.S.)

FDA

Food and Drug Administration (U.S.)

FEDRIP

Federal Research in Progress (U.S.)

FEMA

Federal Emergency Management Agency (U.S.)

FEV1

forced expiratory volume


GLP

Good Laboratory Practices

GSA

General Services Administration (U.S.)


HEAST

Health Effects Assessment Tables

HSDB

Hazardous Substances Data Base

HUD

Department of Housing and Urban Development (U.S.)


IARC

International Agency for Research on Cancer

IDLH

immediately dangerous to life and health (U.S. NIOSH)

IPCS

International Programme for Chemical Safety

IRIS

Integrated Risk Information System (U.S. EPA)


LC01

lethal concentration, 1% lethality

LC50

lethal concentration, 50% lethality

LCL

lower confidence limit

LOAEL

lowest-observed-adverse-effect level


MAC

minimum alveolar concentration

MAC

maximum acceptable concentration (The Netherlands)

MAK

maximale arbeitsplatzkonzentration [maximum workplace concentration] 8-h time-weighted average (German Research Association)

Suggested Citation:"C Glossary of Acronyms, Abbreviations, and Symbols." National Research Council. 2001. Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals. Washington, DC: The National Academies Press. doi: 10.17226/10122.
×

MAK. S

spitzenbegrenzung (kategorie ii, 2) [MAK peak limit (category II, 2)] 30 min×2 per day (Germany)

MCS

multiple chemical sensitivity

MF

modifying factor

MLE

maximum likelihood estimate

MLE01

maximum likelihood estimate, 1% response

MTD

maximum tolerated dose


N/A

not applicable

NAAQS

National Ambient Air Quality Standards (U.S.)

NAC

National Advisory Committee

NAC/AEGL

National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances (NAC/AEGL Committee)

NAS

National Academy of Sciences (U.S.)

NASA

National Aeronautical and Space Administration (U.S.)

NCI

National Cancer Institute (U.S.)

NIOSH

National Institute for Occupational Safety and Health (U.S.)

NOAEL

no-observed-adverse-effect level

NRC

National Research Council (U.S.)

NRC/AEGL

National Research Council Subcommittee on Acute Exposure Guideline Levels (NRC/AEGL Subcommittee) (U.S.)

NSF

National Science Foundation (U.S.)

NTIS

National Technical Information Service (U.S.)

NTP

National Toxicology Program (U.S.)


OECD

Organization for Economic Cooperation and Development

ORNL

Oak Ridge National Laboratories (U.S.)

OSHA

Occupational Safety and Health Administration (U.S.)

OSWER

Office of Solid Waste and Emergency Response (U.S.)


PEL-TWA

permissible exposure limit-time-weighted average (U.S. OSHA)

PEL-STEL

permissible exposure limit-short-term exposure limit (U.S. OSHA)


QA

quality assurance

QC

quality control

QSARs

quantitative structure activity relationships


REL-STEL

recommended exposure limit-short-term exposure limit (U.S. NIOSH)

REL-TWA

recommended exposure limits-time-weighted average (U.S. NIOSH)

RfC

reference concentration (U.S. EPA)

RfD

reference dose (U.S. EPA)

RTECS

Registry of Toxic Effects of Chemical Substances

Suggested Citation:"C Glossary of Acronyms, Abbreviations, and Symbols." National Research Council. 2001. Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals. Washington, DC: The National Academies Press. doi: 10.17226/10122.
×

SARA

Superfund Amendments and Reauthorization Act (CERCLA)

SMAC

spacecraft maximum allowable concentrations

SOP

standing operating procedures

SPEGL

short-term public emergency guidance levels (U.S. NRC)

STPL

short-term public limit (U.S. NRC)


TARA

Toxicology and Risk Assessment Document List (U.S. ORNL)

TLV-STEL

Threshold Limit Value-short-term exposure limit (ACGIH)

TLV-TWA Threshold Limit Value-time-weighted average (ACGIH)

TSD

technical support document


UF

uncertainty factor


WEEL

workplace environmental exposure level (AIHA)

>

greater than

greater than or equal to

<

less than

less than or equal to

%

percent

dL

deciliter

g

gram

h

hour

µm

micrometer

µg

microgram

mg

milligram

min

minute

mL

milliliter

mm

millimeter

ppb

parts per billion

ppm

parts per million

ppt

parts per trillion

Suggested Citation:"C Glossary of Acronyms, Abbreviations, and Symbols." National Research Council. 2001. Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals. Washington, DC: The National Academies Press. doi: 10.17226/10122.
×
Page 175
Suggested Citation:"C Glossary of Acronyms, Abbreviations, and Symbols." National Research Council. 2001. Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals. Washington, DC: The National Academies Press. doi: 10.17226/10122.
×
Page 176
Suggested Citation:"C Glossary of Acronyms, Abbreviations, and Symbols." National Research Council. 2001. Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals. Washington, DC: The National Academies Press. doi: 10.17226/10122.
×
Page 177
Suggested Citation:"C Glossary of Acronyms, Abbreviations, and Symbols." National Research Council. 2001. Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals. Washington, DC: The National Academies Press. doi: 10.17226/10122.
×
Page 178
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Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals contains a detailed and comprehensive methodology for developing acute exposure guideline levels (AEGLs) for toxic substances from inhalation exposures.

The book provides guidance on what documents and databases to use, toxicity endpoints that need to be evaluated, dosimetry corrections from animal to human exposures, selection of appropriate uncertainty factors to address the variability between animals and humans and within the human population, selection of modifying factors to address data deficiencies, time scaling, and quantitative cancer risk assessment.

It also contains an example of a summary of a technical support document and an example of AEGL derivation. This book will be useful to persons in the derivation of levels from other exposure routes—both oral and dermal—as well as risk assessors in the government, academe, and private industry.

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