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Suggested Citation:"Appendix D." National Research Council. 1996. Guide for the Care and Use of Laboratory Animals -- Russian Version. Washington, DC: The National Academies Press. doi: 10.17226/10498.
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Page 123
Suggested Citation:"Appendix D." National Research Council. 1996. Guide for the Care and Use of Laboratory Animals -- Russian Version. Washington, DC: The National Academies Press. doi: 10.17226/10498.
×
Page 124
Suggested Citation:"Appendix D." National Research Council. 1996. Guide for the Care and Use of Laboratory Animals -- Russian Version. Washington, DC: The National Academies Press. doi: 10.17226/10498.
×
Page 125

Below is the uncorrected machine-read text of this chapter, intended to provide our own search engines and external engines with highly rich, chapter-representative searchable text of each book. Because it is UNCORRECTED material, please consider the following text as a useful but insufficient proxy for the authoritative book pages.

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124 I7PB~O~EH~E ~ - upunqanbi uT#E~BL~ u npuMenenu~ XTB~BKM COCTO~HHIO8KCHepUMeHTa~BH~X~K~BOTH~X. B 06~3aHHOCT~KOMUCCHUBXO~HT paCHpOCTpaHeHHe UH~OpMa~H, KOOp~HHa~H HpOrpaMM ~ yHaCTHe B paSpa60TKe HO~HT~KH Be~OMCTB. p~H~HbIDpaB~Te~bCTBa CiCL\B OTHO~eHMM Hp~MeHeHMB ~ CO~ep~aHMB H03BOHOqHbIX ^MBOTHbIX,HCHO~b3yeMbIX B MCHbITaHM~X,HCC~e~OBaHM~X ~ oGyqeH~ Pa3BUTHe HEX SHaHHU, HeO6XO~HM~X ~~H y~yH~eHUH 3~OpOBB~ Earth He~oBeKa7 a TaK*e Pyrex *HBoTH~X,Tpe6yeT HpOBe~eHUH ~KCHepUMeHTOB in vivo Ha ~K~BOTHuX CaM~X pa3H~X BLOB. Ape paSpa60TKe KpUTepHeB ~~H HpOBe~eHH~ ~CH~TaHHU, ~CC~e~OBaHHU H~H oGy~eHn~ c lICTIO3IB3 OB aHHeM H03B OHO~HEIX *HB OTHEIX ro chap CTB eHHEIe yap em CHAR CJ~IA ~O~*HEI HpH~ep*HBaTBCH yKa3aHHEIX HH*e Hp~H~HOB; HpH HeHOCpe~CTBeHHOM BBIHO~HeHHU ~H HO~ep*Ke H0~06HEIX MepOUpH~THU O~Ha~EHEIU upe~cTasuTe~ ~aHHoro y~pe~eHn~ ~o~*eH obecne~nT~ C06~IO~eHHe BTUX Hp~H~HOB: I. TpaHCHOpTHpOBKa, CO~ep~aHHe ~ ~CHO~B30BaHHe *HBOTHEIX OCy~eCTB~SlIOTCH B COOTBeTCTBHU C 3aKOHOM O 3a~HTe ~BOTHEIX (7 U.S.C. 2131 et seq.) ~ ,~pyrnMn cooTseTcTsyIomuMn ~e,~epa~BH~IMn 3aKoHaMn, pyKOBO~CTBaMH1 ~ HpaB~aMH. II. IlpOLle,~ypLI, lIpe,~yCMaTpUBaIO~He ~CTIOJIB30BaHHe *HBOTHEIX, C3Ie~yeT ~aHUpOBaTB ~ BBIHO~H~TB C y~eTOM T~aTe~BHOrO paCCMOTpeH~ UX 3HalIeH~ ~H 3~0pOBB~ He~OBeKa ~H CaM~X ~BOTHEIX, Hporpecca HayKH 6~arococTo~H~ scero o6mecTsa. III.,~ ~KCHepUMeHTOB C~e~yeT OT6HpaTB 3~0pOBBIX *HBOTHEIX COOTBeTCTByIO~erO BH~a, orpaHn~nsa~cB M~HUMa~BHEIM KO~HeCTBOM, HeO6XO~HMBIM ~H HO~yUeHH~ ~OCTOBepHEIX Hay~HEIX pe3y~BTaTOB. HeO6XO~HMO yHUTEIBaTB B03MO*HOCTB ~CHO~B30BaHH~ TaKHX MeTO~OB, KaK MaTeMaTlIIIeCKOe MO~e~HpOBaHHe, KOM0BIOTepHOe MO~e~HpOBaHHe ~ rIpuMeHeHHe 6Ho~ornHecKHx cHcTeM in vitro. IV. 06~3aTe~BHEIM Tpe60BaHHeM ~B~HeTCH lIpaB ~ BHOe ~CTIO~B30BaHHe *HBOTHEIX, KOTOpOe Tpe6yeT yCTpaHeHH~ H~H CBe~eHH~ ~0 M~HUMyMa HCKOMC JOpTa, CTpa~aHHU ~ ~HCTpeCCa B TOH CTeHeHU, B KOTOpOH 3TO COBMeCTHMO C pa~HOHa~BHOH ~KCHepUMeHTa~BHOH HpaKT~KOH. upH OTCyTcTBHn ,~pyrux ~aHHEIX ncc~e~osaTe~n ~O~*HEI ~CXO~HTB H3 TOrO, HTO lIpO~e~ypLI, KOTOpLIe BBI3BIBaIOT 60~B H~H ~HCTpeCC y He~OBeKa, MOryT Hp~HHSITB 60~B ~H ~HCTpeCC ~ ~pyrUM ~BOTHEIM. V. IlpO~e~ypLI, MOry~He BBI3BaTB 60~B ~H ~HCTpeCC, KOTOpLIe He~B3H CIIlITaTB KpaTKOBpeMeHHEIMU H~H M~HUMa~BHEIM~, C~e~yeT BBIHO~H~TB C IplIMeHeHlIeM Ha,~e~am~x Ce~aTHBHEIX Cpe~CTB, aHa~BreT~KOB H~n aHecTeT~KoB. x~pypr~ecKne ~,~pyrne 60JIe3HeHHEIe HpO~e~ypLI He ~O~*HEI HpOBO~HTCH Ha HeaHeCTe3HpOBaHHEIX *HBOTHEIX, 06e3~B~eHHEIX C HOMO~BIO MlIOpe3IaKCaHTOB . VI. *lIBOTHEIX, KOTOpLIe B HpOTHBHOM c~y~ae 6y~yT ncn~IT~IsaTB He r~o,~,~a~omnec~ yCTpaHeHn~O C~H~Ie ~n r~OCTO~HH~Ie 60~n ~n ,~ncTpecc, CJIe~yeT yMep~B~TB 6e360~e3HeHHEIM CHoC060M B KOH~e HpO~e~ypLI ~H, HpH Heo6Xo~HMocTH, B upouccce ee s~Ino~HeHn~. VII. YCJIOBTISI CO~ep~aHH~ *HBOTHEIX ~O~*HEI COOTBeTCTBOBaTB BH~y Ha BCeM HpOTSDKeHHU ~aHH~X Hp~H~HOB HUTaTe~b OTCbMaeTCH K <<PYKOBO~CTBY HO CO~ep~aHHIO ~ ~CHO~bSOBaHHIO ~a60paTOpH~X ~BOTH~X>>, HO~rOTOB~eHHOMy IIHCTHTYTOM peCypCOB ~a60paTOpH~X *HBOTH~X Ha~HOHa~bHOH aKa~eMHU HayK.

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