National Academies Press: OpenBook

Gulf War and Health: Volume 2: Insecticides and Solvents (2003)

Chapter: Appendix G: Consensus Conclusions Arranged by Health Outcome

« Previous: Appendix F: Neurologic Examination
Suggested Citation:"Appendix G: Consensus Conclusions Arranged by Health Outcome." Institute of Medicine. 2003. Gulf War and Health: Volume 2: Insecticides and Solvents. Washington, DC: The National Academies Press. doi: 10.17226/10628.
×

G
CONSENSUS CONCLUSIONS ARRANGED BY HEALTH OUTCOME

Cancer

Sufficient Evidence of a Causal Relationship

  • Benzene and acute leukemia

Sufficient Evidence of an Association

  • Benzene and adult leukemia

  • Solvents and acute leukemia

Limited/Suggestive Evidence of an Association:

  • Tetrachloroethylene and dry-cleaning solvents and bladder cancer

  • Solvents and bladder cancer

  • Tetrachloroethylene and dry-cleaning solvents and kidney cancer

  • Organophosphorous insecticides and non-Hodgkin’s lymphoma

  • Carbamates and non-Hodgkin’s lymphoma

  • Benzene and non-Hodgkin’s lymphoma

  • Solvents and multiple myeloma

  • Organophosphorous insecticides and adult leukemia

  • Solvents and adult leukemia

  • Solvents and myelodysplastic syndromes

Inadequate/Insufficient Evidence to Determine Whether an Association Exists:

  • Solvents and oral, nasal, or laryngeal cancer

  • Insecticides and pancreatic cancer

  • Solvents other than tetrachloroethylene and dry-cleaning solvents and esophageal cancer

  • Solvents and stomach, rectal, or pancreatic cancer

  • Solvents other than trichloroethylene and mixtures of benzene, toluene, and xylene and colon cancer

  • Insecticides and solvents and hepatobiliary cancers

  • Insecticides and lung cancer

  • Solvents other than tetrachloroethylene and dry-cleaning solvents and lung cancer

Suggested Citation:"Appendix G: Consensus Conclusions Arranged by Health Outcome." Institute of Medicine. 2003. Gulf War and Health: Volume 2: Insecticides and Solvents. Washington, DC: The National Academies Press. doi: 10.17226/10628.
×
  • Solvents and bone cancer

  • Solvents and melanoma or nonmelanoma skin cancer

  • Insecticides and soft tissue sarcomas

  • Lindane and solvents and breast cancer

  • Solvents other than trichloroethylene and cervical cancer

  • Solvents and ovarian or uterine cancer

  • Insecticides and prostate, testicular, bladder, or kidney cancers

  • Specific solvents other than tetrachloroethylene and dry-cleaning solvents and bladder cancer

  • Solvents other than tetrachloroethylene and dry-cleaning solvents and kidney cancer

  • Solvents and prostate cancer

  • Insecticides and brain and other central nervous system cancers

  • Specific solvents other than benzene and brain and other central nervous system cancers

  • Specific solvents other than benzene and non-Hodgkin’s lymphoma

  • Insecticides and solvents and Hodgkin’s disease

  • Insecticides and specific solvents and multiple myeloma

  • Specific solvents other than benzene and acute and adult leukemia

  • Benzene and myelodysplastic syndrome

  • Parental preconception exposure to insecticides and childhood leukemias, brain and other central nervous system cancers or non-Hodgkin’s lymphoma

  • Parental preconception exposure to solvents and neuroblastoma or childhood brain cancers

Limited/Suggestive Evidence of NO Association

  • No findings

Neurologic Effects

Sufficient Evidence of a Causal Relationship

  • No findings

Sufficient Evidence of an Association

  • No findings

Limited/Suggestive Evidence of an Association:

  • Organophosphorous insecticide exposure with OP poisoning and long-term neurobehavioral effects (that is, abnormal results on neurobehavioral test batteries and symptom findings)

  • Solvents and neurobehavioral effects (that is, abnormal results on neurobehavioral test batteries and symptom findings)

Suggested Citation:"Appendix G: Consensus Conclusions Arranged by Health Outcome." Institute of Medicine. 2003. Gulf War and Health: Volume 2: Insecticides and Solvents. Washington, DC: The National Academies Press. doi: 10.17226/10628.
×

Inadequate/Insufficient Evidence to Determine Whether an Association Exists:

  • Insecticides and solvents and peripheral neuropathy

  • Insecticides and solvents and Parkinson’s Disease

  • Insecticides and solvents and amyotrophic lateral sclerosis

  • Insecticides and solvents and Alzheimer’s Disease

  • Solvents and multiple sclerosis

  • Solvents and a long-term reduction in color discrimination

  • Solvents and long-term hearing loss

  • Solvents and long-term reduction in olfactory function

Limited/Suggestive Evidence of NO Association

  • No findings

Reproductive Effects

Sufficient Evidence of a Causal Relationship

  • No findings

Sufficient Evidence of an Association

  • No findings

Limited/Suggestive Evidence of an Association:

  • No findings

Inadequate/Insufficient Evidence to Determine Whether an Association Exists:

  • Insecticides and solvents and male or female infertility after cessation of the exposure

  • Parental preconception exposure to insecticides or solvents and spontaneous abortion or other adverse pregnancy outcomes

  • Parental preconception exposure to insecticides or solvents and congenital malformations

Limited/Suggestive Evidence of NO Association

  • No findings

Other Health Effects

Sufficient Evidence of a Causal Relationship

  • Benzene and aplastic anemia

Sufficient Evidence of an Association

  • Propylene glycol and allergic contact dermatitis

Suggested Citation:"Appendix G: Consensus Conclusions Arranged by Health Outcome." Institute of Medicine. 2003. Gulf War and Health: Volume 2: Insecticides and Solvents. Washington, DC: The National Academies Press. doi: 10.17226/10628.
×

Limited/Suggestive Evidence of an Association:

  • Solvents and reactive airways dysfunction syndrome (RADS) which would be evident with exposure and could persist for months or years

  • Solvents and hepatic steatosis

  • Solvents and chronic glomerulonephritis

  • Insecticides and allergic contact dermatitis

Inadequate/Insufficient to Determine Whether an Association Exists:

  • Insecticides and aplastic anemia

  • Solvents other than benzene and aplastic anemia

  • Insecticides and solvents and irreversible cardiovascular outcomes

  • Insecticides and solvents and persistent respiratory symptoms or impairment after cessation of exposure

  • Solvents and alterations in liver function tests after cessation of exposure

  • Solvents and cirrhosis

  • Solvents and chronic pancreatitis or other persistent gastrointestinal outcomes

  • Solvents and the systemic rheumatic diseases: scleroderma, rheumatoid arthritis, undifferentiated connective tissue disorders, and systemic lupus erythematosus

Limited/Suggestive Evidence of NO Association

  • No finding

Suggested Citation:"Appendix G: Consensus Conclusions Arranged by Health Outcome." Institute of Medicine. 2003. Gulf War and Health: Volume 2: Insecticides and Solvents. Washington, DC: The National Academies Press. doi: 10.17226/10628.
×
Page 580
Suggested Citation:"Appendix G: Consensus Conclusions Arranged by Health Outcome." Institute of Medicine. 2003. Gulf War and Health: Volume 2: Insecticides and Solvents. Washington, DC: The National Academies Press. doi: 10.17226/10628.
×
Page 581
Suggested Citation:"Appendix G: Consensus Conclusions Arranged by Health Outcome." Institute of Medicine. 2003. Gulf War and Health: Volume 2: Insecticides and Solvents. Washington, DC: The National Academies Press. doi: 10.17226/10628.
×
Page 582
Suggested Citation:"Appendix G: Consensus Conclusions Arranged by Health Outcome." Institute of Medicine. 2003. Gulf War and Health: Volume 2: Insecticides and Solvents. Washington, DC: The National Academies Press. doi: 10.17226/10628.
×
Page 583
Next: Index »
Gulf War and Health: Volume 2: Insecticides and Solvents Get This Book
×
Buy Paperback | $150.00 Buy Ebook | $119.99
MyNAP members save 10% online.
Login or Register to save!
Download Free PDF

Gulf War and Health, Volume 2, is the second in a series of congressionally-mandated studies by the Institute of Medicine that provides a comprehensive assessment of the available scientific literature on potential health effects of exposure to certain biological, chemical, and environmental agents associated with the Gulf War. In this second study, the committee evaluated the published, peer-reviewed literature on exposure to insecticides and solvents thought to have been present during the 1990-1991 war.

Because little information exists on actual exposure levels – a critical factor when assessing health effects – the committee could not draw specific conclusions about the health problems of Gulf War veterans. However, the study found some evidence, although usually limited, to link specific long-term health outcomes with exposure to certain insecticides and solvents.

The next phase of the series will examine the literature on potential health effects associated with exposure to selected environmental pollutants and particulates, such as oil-well fires and jet fuels.

  1. ×

    Welcome to OpenBook!

    You're looking at OpenBook, NAP.edu's online reading room since 1999. Based on feedback from you, our users, we've made some improvements that make it easier than ever to read thousands of publications on our website.

    Do you want to take a quick tour of the OpenBook's features?

    No Thanks Take a Tour »
  2. ×

    Show this book's table of contents, where you can jump to any chapter by name.

    « Back Next »
  3. ×

    ...or use these buttons to go back to the previous chapter or skip to the next one.

    « Back Next »
  4. ×

    Jump up to the previous page or down to the next one. Also, you can type in a page number and press Enter to go directly to that page in the book.

    « Back Next »
  5. ×

    Switch between the Original Pages, where you can read the report as it appeared in print, and Text Pages for the web version, where you can highlight and search the text.

    « Back Next »
  6. ×

    To search the entire text of this book, type in your search term here and press Enter.

    « Back Next »
  7. ×

    Share a link to this book page on your preferred social network or via email.

    « Back Next »
  8. ×

    View our suggested citation for this chapter.

    « Back Next »
  9. ×

    Ready to take your reading offline? Click here to buy this book in print or download it as a free PDF, if available.

    « Back Next »
Stay Connected!