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Sleep Disorders and Sleep Deprivation: An Unmet Public Health Problem (2006)

Chapter: Appendix F National Institutes of Health Sleep-Related Initiatives: 1994-2004

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Suggested Citation:"Appendix F National Institutes of Health Sleep-Related Initiatives: 1994-2004 ." Institute of Medicine. 2006. Sleep Disorders and Sleep Deprivation: An Unmet Public Health Problem. Washington, DC: The National Academies Press. doi: 10.17226/11617.
×

F
National Institutes of Health Sleep-Related Initiatives: 1994–2004

Suggested Citation:"Appendix F National Institutes of Health Sleep-Related Initiatives: 1994-2004 ." Institute of Medicine. 2006. Sleep Disorders and Sleep Deprivation: An Unmet Public Health Problem. Washington, DC: The National Academies Press. doi: 10.17226/11617.
×

TABLE F-1 Sleep Initiatives (RFAs) Sponsored by the National Institutes of Health, 1994–2004

Title

Primary Purpose

Participating Institutes/Centers

Funding Activity

Year

SCOR in Neurobiology of Sleep & Sleep Apnea: RFA-HL-96-014

Establish specialized centers of research (SCORs) programs to foster translational research.

NHLBI

P50

1996

Molecular Biology and Genetics of Sleep and Sleep Disorders: RFA-HL-96-015

Advance the understanding of the molecular and genetic basis of sleep and sleep disorders.

NHLBI, NIMH, NICHD

R01

1996

Sleep Academic Award: HL-97-015; HL-96-021

Develop and/or improve the quality of medical curricula for the prevention, management, and control of sleep disorders.

NHLBI

K07

1996, 1997

Obstructive Sleep Apnea in Children: HL-98-004

Define abnormalities in airway structure and function responsible for obstructive sleep apnea in children, and identify physiological and clinical measures associated with increased morbidity.

NHLBI, NIDR, NICHD

R01

1997

Phenotypic Characterization of Sleep in Mice: RFA-HL-99-001

Develop improved molecular, cellular, and systems approaches to investigate sleep and circadian phenotypes in mice.

NHLBI, NIMH, NIA, NINDS

R01

1998

Nocturnal Asthma, Chronobiology, and Sleep: RFA-HL-99-011

Establish the mechanisms that underlie the chronobiology of nocturnal exacerbations of asthma and airway inflammation, as well as the role played by sleep and sleep disturbances.

NHLBI

R01

1999

Implementation of the National Occupational Research Agenda: RFA-OH-99-002

Develop knowledge that can be used in preventing occupational diseases and injuries and to better understand their underlying pathophysiology.

NIOSH, NCI, NHLBI, NIA, NIDCD, NIEHS

R01, R18

1999

Data Coordinating Center for Sleep Heart Health Study: RFA-HL-99-014

Establish a new data coordinating center for the Sleep Heart Health Study.

NHLBI

U01

1999

Research on Alcohol and Sleep: RFA-AA-00-005

Stimulate research on alcohol and sleep in areas that may improve understanding of the etiology and treatment of alcoholism.

NIAAA

R01, R21

2000

Suggested Citation:"Appendix F National Institutes of Health Sleep-Related Initiatives: 1994-2004 ." Institute of Medicine. 2006. Sleep Disorders and Sleep Deprivation: An Unmet Public Health Problem. Washington, DC: The National Academies Press. doi: 10.17226/11617.
×

Oxygen Sensing During Intermittent Hypoxia: RFA-HL-00-004

Improve understanding of how intermittent hypoxia contributes to the pathophysiology of cardiopulmonary, vascular, hematological, and sleep disorders.

NHLBI

R01

2000

Ancillary Studies in Conjunction with SHOW Trial: RFA-DK-00-017

Develop basic, clinical, and behavioral ancillary research studies of the Study of Health Outcomes of Weight-Loss (SHOW) clinical trial.

NIDDK, NHLBI, NINR, NIAMS, NIDCR

R01

2000

Interrelationships Between Sleep and Heart, Lung, and Blood Diseases: RFA-HL-01-009

Elucidate characteristics of sleep physiology, sleep disorders, and pathophysiological mechanisms mediating the interrelationship between sleep disturbance and heart, lung, and blood diseases.

NHLBI, NIDA

R01

2001

Sleep and Sleep Disorders in Children: RFA-HL-01-006

Improve the understanding of fundamental biological mechanisms through which sleep deprivation and sleep disorders affect the cardiopulmonary, hematological, immunological, mental, and behavioral health of children.

NHLBI, NIMH, NINR, NICHD

R01

2001

Role of Sleep and Sleep Disordered Breathing in the Metabolic Syndrome: RFA-HL-03-008

Elucidate the relationship of sleep deprivation and sleep-disordered breathing to characteristics of the metabolic syndrome including obesity, high blood pressure, dyslipidemia, insulin resistance, and vascular inflammation.

NHLBI, NIA

R01

2002

Inter-relationships of Sleep, Fatigue, and HIV/AIDS: RFA-HL-04-010

Elucidate the etiology of sleep disturbances and fatigue associated with human immunodeficiency virus infection and acquired immunodeficiency disease syndrome.

NHLBI, NIMH

R01

2003

NOTE: Primary purpose of each PA and RFA are adapted from language in NIH announcements. NCCAM = National Center for Complementary and Alternative Medicine; NCI = National Cancer Institute; NCSDR = National Center on Sleep Disorders Research; NHLBI = National Heart, Lung, and Blood Institute; NIA = National Institute on Aging; NIAAA = National Institute on Alcohol Abuse and Alcoholism; NIAID = National Institute of Allergy and Infectious Diseases; NIAMS = National Institute of Arthritis and Musculoskeletal and Skin Diseases; NICHD = National Institute of Child Health and Human Development; NIDA = National Institute on Drug Abuse; NIDCD = National Institute on Deafness and Other Communication Disorders; NIDCR = National Institute of Dental and Craniofacial Research; NIDDK = National Institute of Diabetes and Digestive and Kidney Diseases; NIDR = National Institute of Dental Research; NIEHS = National Institute of Environmental Health Sciences; ; NIH= National Institutes of Health; NIMH = National Institute of Mental Health; NINDS = National Institute of Neurological Disorders and Stroke; NINR = National Institute of Nursing Research; NIOSH = National Institute for Occupational Safety and Health; PA = program announcement; RFA = request for application.

SOURCE: National Heart, Lung, and Blood Institute, 2003; National Sleep Disorders Research Plan, 2003 Bethesda, MD: NIH.

Suggested Citation:"Appendix F National Institutes of Health Sleep-Related Initiatives: 1994-2004 ." Institute of Medicine. 2006. Sleep Disorders and Sleep Deprivation: An Unmet Public Health Problem. Washington, DC: The National Academies Press. doi: 10.17226/11617.
×

TABLE F-2 Sleep Initiatives (PAs) Sponsored by the National Institutes of Health, 1994–2004

Title

Primary Purpose

Participating Institutes/Centers

Funding Activity

Year

Basic and Clinical Research Sleep & Wakefulness: PA-95-014

Enhance sleep research in the following areas: neuroscienceon and behavioral science; molecular and cellular mechanisms of sleep and circadian rhythms across the life span; development of sleep from fetal life through infancy; role of dreaming in humans; etiological factors and pathophysiology of transient or persistent insomnia; and the treatment of sleep disorders.

NIA, NIAAA, NICHD, NIDA, NHLBI, NIMH, NINDS, NINR

R01, R03, R29, P01

1994

Innovative Approaches to Developing New Technologies: PA-97-014

Support research to identify, create, and develop innovative technologies and to provide these technologies for biomedical research.

NCRR

R21

1996

Research on Musculoskeletal Fitness and Sports Medicine: PA-97-025

Study a broad range of basic and clinical topics related to musculoskeletal fitness, exercise physiology, and sports medicine.

NIAMS, NICHD, NINR

R01, R03, R29, K01, K02, K08, P01

1997

Institutional National Research Service Award in Sleep Research: PA-97-064

Ensure that scientists, highly trained in sleep research, are available in adequate numbers to address important gaps in our biomedical and biological understanding of sleep, including those outlined in the NIH director’s Sleep Disorders Research Plan.

NHLBI, NIA, NIAAA, NICHD, NIDA, NIMH, NINDS, NINR

T32

1997

Bioengineering Research Grants: PAR-99-009

Support basic bioengineering research whose outcomes are likely to advance health or health-related research within the mission of the NIH.

NCI, NCRR, NEI, NHGRI, NHLBI, NIA, NIAAA, NIAID, NIAMS, NICHD, NIDA, NIDCD, NIMH, NINDS, NINR, NLM

R01

1998

Suggested Citation:"Appendix F National Institutes of Health Sleep-Related Initiatives: 1994-2004 ." Institute of Medicine. 2006. Sleep Disorders and Sleep Deprivation: An Unmet Public Health Problem. Washington, DC: The National Academies Press. doi: 10.17226/11617.
×

Human Brain Project (Neuroinformatics): PAR-99-138

Encourage and support investigator-initiated, neuroinformatics research that will lead to new digital and electronic tools for all domains of neuroscience research.

NIMH, NIDA, NSF, NIA, NICHD, NIDCD, NLM, NASA, FIC, DOE, NIAAA, NHLBI, NIDCR, NCI, NINDS

R01, P01, P20

1999

Occupational Safety and Health Research: PA-99-143

Develop knowledge that can be used in preventing occupational diseases and injuries, and better understand their underlying pathophysiology.

NIOSH, NCI, NHLBI, NIA, NIAAA, NIAID, NIAMS, NIDCD, NIEHS

R01

1999

Restless Legs Syndrome and Periodic Limb Movement Disorder: PA-01-086

Develop an understanding of the pathogenesis of RLS and PLMD that will lead to new forms of treatment.

NINDS, NHLBI, NIA, NIMH

R01

2001

Research on Sleep and Sleep Disorders: PA-05-046

Advance biomedical knowledge related to sleep or sleep disorders; improve understanding of the neurobiology or functions of sleep over the life span; enhance timely diagnosis and effective treatment for individuals affected by sleep-related disorders; or implement and evaluate innovative community-based public health education and intervention programs.

NHLBI, NCSDR, NIA, NIAAA, NIAMS, NCI, NICHD, NCCAM, NIDA, NIMH, NINDS, NINR, ORWH

R01, R21

2004

NOTE: Primary purpose of each PA and RFA are adapted from language in NIH announcements. DOE = Department of Energy; FIC = Fogarty International Center; NASA = National Aeronautics and Space Administration; NCCAM = National Center for Complementary and Alternative Medicine; NCI = National Cancer Institute; NCRR = National Center for Research Resources; NCSDR = National Center on Sleep Disorders Research; NEI = National Eye Institute; NHGRI = National Human Genome Research Institute; NHLBI = National Heart, Lung, and Blood Institute; NIA = National Institute on Aging; NIAAA = National Institute on Alcohol Abuse and Alcoholism; NIAID = National Institute of Allergy and Infectious Diseases; NIAMS = National Institute of Arthritis and Musculoskeletal and Skin Diseases; NICHD = National Institute of Child Health and Human Development; NIDA = National Institute on Drug Abuse; NIDCD = National Institute on Deafness and Other Communication Disorders; NIDCR = National Institute of Dental and Craniofacial Research; NIEHS = National Institute for Environmental Health Sciences; NIH= National Institutes of Health; NIMH = National Institute of Mental Health; NINDS = National Institute of Neurological Disorders and Stroke; NINR = National Institute of Nursing Research; NIOSH = National Institute for Occupational Safety and Health; NLM = National Library of Medicine; NSF= National Sleep Foundation; ORWH = Office of Research on Women’s Health; PA = program announcement; RFA = request for application.

SOURCES: National Heart Lung and Blood Institute, 2003; National Sleep Disorders Research Plan, 2003.Bethesda, MD: NIH.

Suggested Citation:"Appendix F National Institutes of Health Sleep-Related Initiatives: 1994-2004 ." Institute of Medicine. 2006. Sleep Disorders and Sleep Deprivation: An Unmet Public Health Problem. Washington, DC: The National Academies Press. doi: 10.17226/11617.
×
Page 351
Suggested Citation:"Appendix F National Institutes of Health Sleep-Related Initiatives: 1994-2004 ." Institute of Medicine. 2006. Sleep Disorders and Sleep Deprivation: An Unmet Public Health Problem. Washington, DC: The National Academies Press. doi: 10.17226/11617.
×
Page 352
Suggested Citation:"Appendix F National Institutes of Health Sleep-Related Initiatives: 1994-2004 ." Institute of Medicine. 2006. Sleep Disorders and Sleep Deprivation: An Unmet Public Health Problem. Washington, DC: The National Academies Press. doi: 10.17226/11617.
×
Page 353
Suggested Citation:"Appendix F National Institutes of Health Sleep-Related Initiatives: 1994-2004 ." Institute of Medicine. 2006. Sleep Disorders and Sleep Deprivation: An Unmet Public Health Problem. Washington, DC: The National Academies Press. doi: 10.17226/11617.
×
Page 354
Suggested Citation:"Appendix F National Institutes of Health Sleep-Related Initiatives: 1994-2004 ." Institute of Medicine. 2006. Sleep Disorders and Sleep Deprivation: An Unmet Public Health Problem. Washington, DC: The National Academies Press. doi: 10.17226/11617.
×
Page 355
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Clinical practice related to sleep problems and sleep disorders has been expanding rapidly in the last few years, but scientific research is not keeping pace. Sleep apnea, insomnia, and restless legs syndrome are three examples of very common disorders for which we have little biological information. This new book cuts across a variety of medical disciplines such as neurology, pulmonology, pediatrics, internal medicine, psychiatry, psychology, otolaryngology, and nursing, as well as other medical practices with an interest in the management of sleep pathology. This area of research is not limited to very young and old patients—sleep disorders reach across all ages and ethnicities. Sleep Disorders and Sleep Deprivation presents a structured analysis that explores the following:

  • Improving awareness among the general public and health care professionals.
  • Increasing investment in interdisciplinary somnology and sleep medicine research training and mentoring activities.
  • Validating and developing new and existing technologies for diagnosis and treatment. This book will be of interest to those looking to learn more about the enormous public health burden of sleep disorders and sleep deprivation and the strikingly limited capacity of the health care enterprise to identify and treat the majority of individuals suffering from sleep problems.
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