Committee on Asbestos: Selected Health Effects
Jonathan M. Samet, M.D., M.S. (Chair, IOM Member), is professor and chairman of the Department of Epidemiology at the Johns Hopkins Bloomberg School of Public Health. He earned his M.D. from the University of Rochester School of Medicine and Dentistry and an M.S. in epidemiology from the Harvard School of Public Health. He is board-certified in internal medicine and the subspecialty of pulmonary disease. He was formerly professor and chief of the Pulmonary and Critical Care Division in the Department of Medicine at the University of New Mexico School of Medicine. He is past-president of the Society for Epidemiologic Research and the American College of Epidemiology. He has served on the US Environmental Protection Agency Science Advisory Board. He is an editor of Epidemiology. Dr. Samet was awarded the Surgeon General’s Medallion in 1990. He has served in numerous National Academies committees, and chaired the National Research Council Committee on Health Risks of Exposure to Radon (BEIR VI) and the Committee on Research Priorities for Airborne Particulate Matter. He is also the chair of the Research Council’s Board on Environmental Studies and Toxicology. He was elected to the Institute of Medicine (IOM) in 1997.
Lonnie R. Bristow, M.D., M.A.C.P. (IOM Member), was president of the American Medical Association (AMA), after earlier serving as vice chair and chair of the AMA’s Board of Trustees. He is a board-certified internist and has practiced medicine for more than 30 years. Dr. Bristow’s research interests and expertise are eclectic, and over the decades his writings have included papers on medical ethics, socialized medicine as practiced in Great
Britain and Canada, health-care financing in the United States, professional-liability insurance problems, sickle-cell anemia, and coronary-care unit use. Dr. Bristow recently retired from private practice, but continues his other activities as a professional consultant. In addition, he is a reviewer for the Journal of the American Medical Association. He was chair of IOM’s Committee on the Quality of Health Care in America, which wrote the widely read reports To Err Is Human and Crossing the Quality Chasm in 1999 and 2001, respectively. Dr. Bristow was elected to IOM in 1978.
Harvey Checkoway, M.P.H., Ph.D., is professor in the Departments of Environmental and Health Sciences and of Epidemiology at the University of Washington School of Public Health and Community Medicine. He received his M.P.H. from Yale University and his doctorate in epidemiology from the University of North Carolina, Chapel Hill. His research and teaching are in occupational and environmental determinants of chronic diseases. Research projects for which Dr. Checkoway has been principal investigator include epidemiologic studies of cancer mortality in nuclear workers, cancer mortality in phosphate-industry workers, silicosis and lung cancer in silica-exposed diatomaceous-earth industry workers, lung cancer among chromate-exposed aerospace workers, reproductive hazards among lead-smelter workers, and environmental and genetic risk factors for Parkinson’s disease.
Paul Demers, M.Sc., Ph.D., is associate professor at the University of British Columbia School of Occupational and Environmental Hygiene. He obtained his doctorate in epidemiology from the University of Washington. His research interests include occupational cancer, occupational respiratory disease, and occupational risk factors for sinonasal cancer. His current research projects concern cancer among sawmill workers exposed to wood dust and fungicides, occupational noise exposure, and the risk of injuries and heart disease among sawmill workers.
Ellen Eisen, M.S., Sc.D., is adjunct professor in the Department of Environmental Health at the Harvard School of Public Health and professor of epidemiology in the Department of Work Environment at the University of Massachusetts, Lowell. She received an M.S. in biostatistics, an Sc.D. in biostatistics and occupational health from the Harvard School of Public Health, and an M.S. in operations research and statistics from Massachusetts Institute of Technology. Dr. Eisen is interested in a variety of methodologic issues in occupational epidemiology, particularly new statistical methods to improve analysis of exposure-response data. She did early work toward standardizing measurement of pulmonary function for field studies. She has served on several National Academies committees.
George W. Guthrie, M.A., Ph.D., received his M.A. and doctorate in minerology-crystallography from Johns Hopkins University. He is a scientist at Los Alamos National Laboratory with the Geology and Geochemistry Group. His research interests include the health effects of minerals and concrete. Dr. Guthrie is interested in the mineralogic mechanisms that cause disease and is working to identify potential mineralogic properties important in disease, including mineral-catalyzed oxidation-reduction, cation exchange, and surface structure.
Rogene Henderson, Ph.D., D.A.B.T., is deputy director of the National Environmental Respiratory Center and senior biochemist and toxicologist at the Lovelace Respiratory Research Institute. Dr. Henderson also holds appointments as clinical professor of pharmacy at the University of New Mexico, Albuquerque, and as adjunct professor in the Departments of Veterinary Microbiology, Pathology, and Public Health at the School of Veterinary Medicine, Purdue University. She obtained her doctorate in chemistry from the University of Texas, was a Fulbright Scholar in physical chemistry at Ludwig Maximillians Universitaet in Munich, Germany, and is a Diplomate of the American Board of Toxicology. She has chaired the National Research Council (NRC) Subcommittee on Toxicological Hazard and Risk Assessment, Subcommittee on Pulmonary Toxicology, and standing Committee on Toxicology for six years, and she is currently a member of the Board on Environmental Studies and Toxicology. She has served as a member of the advisory council of the National Institute of Environmental Health Sciences (NIEHS) and the U.S. Environmental Protection Agency’s (EPA) Science Advisory Board, Environmental Health Committee. Dr. Henderson has received numerous appointments on scientific advisory committees, including her current appointment as a member of the Health Effects Institute Research Committee. Dr. Henderson has done extensive research in the areas of lung biochemistry, the pharmacokinetics of inhaled toxins and their metabolites, and biological markers of exposure.
Joseph W. Hogan, M.S., Sc.D., is associate professor in the Bisostatistics Section and Center for Statistical Sciences Department of Community Medicine at Brown University. He received a master’s degree in statistics from the University of Southern California and a doctorate in biostatistics from Harvard School of Public Health. His research interests include development of statistical methods for analyzing longitudinal data, for handling missing data, and for causal inference.
Agnes B. Kane, M.D., Ph.D., is professor and chair of the Department of Pathology and Laboratory Medicine at Brown University. She earned her M.D. and Ph.D. in experimental pathology at Temple University School of
Medicine and is board-certified in anatomic pathology. Her research has focused on mechanisms of fiber-induced toxicity, particularly on how asbestos produces mesotheliomas, using genetically engineered murine models, laser microdissection, and cDNA microarrays.
Fadlo R. Khuri, M.D., is professor in the Departments of Hematology, Oncology, Medicine, Pharmacology, and Otolaryngology at the Emory University School of Medicine. He is also associate director of clinical and translational research, chief medical officer, and director of the Aerodigestive Tract Cancer Program at the Winship Cancer Institute at Emory University. He received his M.D. from Columbia University and is board-certified in internal medicine, hematology, and medical oncology. Dr. Khuri’s research focuses on molecular therapeutic and prognostic approaches to tobacco-related cancers. He has been involved in the development of novel agents for aerodigestive tract cancers and has conducted some early phase I and II studies. The goal of his research is to identify specific pathways for better molecular, prognostic, and chemopreventive approaches.
Roberta B. Ness, M.D., M.P.H., is professor and chair of the Department of Epidemiology at the University of Pittsburgh Graduate School of Public Health and director of the school’s Epidemiology of Women’s Health Program, the first university program of its kind in the United States. She received an M.D. from Cornell University and an M.P.H. from Columbia University. In her current position, she oversees a comprehensive effort to improve women’s health through graduate-student education and research.
Michael J. Thun, M.D., M.S., is vice president of epidemiology and surveillance research at the American Cancer Society. He is also clinical professor of hematology and oncology at the Winship Cancer Institute at Emory University. He earned his M.D. from the University of Pennsylvania and his M.S. in epidemiology from the Harvard School of Public Health. Dr. Thun has a wide variety of research interests, including cancer-related aspects of smoking, aspirin and prostaglandins, alcohol abuse, heavy-metal toxicity (particularly cadmium, uranium, lead, and mercury), and occupational renal disease.
Assistants with Graphical Data
Li Su, Ph.D. candidate, Brown University
Yunxia Sui, Ph.D. candidate, Brown University
Rose Marie Martinez, Sc.D., is the director of the IOM Board on Population Health and Public Health Practices. Before joining IOM, she was senior health researcher at Mathematica Policy Research, where she studied the effects of health-system change on the public-health infrastructure, access to care for vulnerable populations, managed care, and the health-care workforce. Dr. Martinez is former assistant director of health financing and policy with the US General Accounting Office, for which she directed evaluations and policy analysis on national and public-health issues. Dr. Martinez received her doctorate from the Johns Hopkins School of Hygiene and Public Health.
Mary Burr Paxton, Ph.D., is a senior program officer in the IOM Board on Population Health and Public Health Practices. Before joining IOM, she worked as a consultant on the regulation of toxic substances and managed the conduct and analysis of several epidemiology studies on veterans’ health. She received a master’s of science in biostatistics from the Johns Hopkins School of Hygiene and Public Health and a doctorate in genetics from the George Washington University. She is a diplomate of the American Board of Toxicology. Dr. Paxton has worked on several National Academies reports, including Issues in Risk Assessment, Environmental Neurotoxicology, Gulf War and Health: Insecticides and Solvents, and Gulf War and Health: Fuels, Combustion Products, and Propellants.
Michael Schneider, M.P.H., is a senior program associate in the IOM Board on Population Health and Public Health Practices. He received his Masters in Public Health and an undergraduate degree in molecular and cellular biology from the University of Arizona. Michael has been with the IOM for over 5 years and has worked on several reports in the Gulf War and Health series.
Tia S. Carter, B.S., is a senior program assistant on the IOM Board on Population Health and Public Health Practices. She is working on a master’s in health-care administration at the University of Maryland University College. She received her undergraduate degree in community health from the University of Maryland, College Park. Before coming to IOM, she worked at the Greater Washington Urban League in the Division of Aging and Health Services as the health promotions coordinator, where she was responsible for health-promotion and disease-prevention education services and activities among the elderly. Asbestos: Selected Cancers is Tia’s first report with IOM.