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Nutrigenomics and Beyond: Informing the Future: Workshop Summary (2007)

Chapter: Appendix B: Workshop Agenda

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Suggested Citation:"Appendix B: Workshop Agenda." Institute of Medicine. 2007. Nutrigenomics and Beyond: Informing the Future: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/11845.
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Appendix B
Workshop Agenda

Nutrigenomics and Beyond: Informing the Future

June 1–2, 2006

National Academy of Sciences Auditorium

2100 C Street, NW

Washington, DC 20037

Day 1

8:30 a.m.

Welcome

Ann Yaktine, Senior Program Officer, Food and Nutrition Board

Robert M. Russell, Chair, Food and Nutrition Board

Harvey V. Fineberg, President of the Institute of Medicine

Nicholas Schork, Food and Nutrition Board Member and Workshop Moderator

8:45

Keynote Address

Why Nutrition and Genomics Are Important

  • Bernadine Healy, U.S. News & World Report

9:30

Introductory Comments on Scientific Sessions

  • John Milner, National Cancer Institute, National Institutes of Health

9:45

Scientific Session I: Human Genetic Variation and Nutrition

Moderator: Nicholas Schork, University of California, San Diego

Suggested Citation:"Appendix B: Workshop Agenda." Institute of Medicine. 2007. Nutrigenomics and Beyond: Informing the Future: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/11845.
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Human Genetic Variation: New Tools for Understanding Its Role in Health and Disease

  • Francis Collins, National Human Genome Research Institute, National Institutes of Health

10:15

Break

10:45

Implementation of the Human HapMap Initiative and Large-Scale Polymorphism Studies

  • David Cox, Perlegen Sciences, Inc.

 

Contemporary Nutrigenetics Studies

  • Jose Ordovas, Tufts University

 

Discussion

11:45

Economic Impact

Estimating the Economic Impact of Nutrigenomics in Managing Health Costs

  • Patricia Danzon, University of Pennsylvania

12:15 p.m.

Lunch

1:15

Scientific Session II: Epigenetics

Moderator: Rowena Matthews, Life Sciences Institute

 

Critical Events; Genomic Programming and Reprogramming

  • Rudolph Jaenisch, Massachusetts Institute of Technology

 

Nutrition Modulation of Epigenetic Programming and Reprogramming

  • Patrick Stover, Cornell University

 

Role of Maternal and Infant Nutrition in Genetic Programming and Epigenetics

  • Cutberto Garza, Boston College

 

Discussion

3:15

Break

Suggested Citation:"Appendix B: Workshop Agenda." Institute of Medicine. 2007. Nutrigenomics and Beyond: Informing the Future: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/11845.
×

3:30

Scientific Session III: Systems Biology

Moderator: Robert Cousins, University of Florida

 

Genetic Networks and Applied Systems Biology

  • C. Ronald Kahn, Joslin Diabetes Center, Harvard University

 

Genome-Scale Reconstruction of the Human Metabolic Network: Basic Concepts and Practical Uses

  • Bernhard Palsson, University of California, San Diego

 

Emerging Technologies Nanotechnology

  • Martin Philbert, University of Michigan

 

Discussion

5:30

Adjourn for the Day

Day 2

8:45 a.m.

Session IV: Implications for the Future

Introduction and Moderator: John Milner

9:00

Issues in Ethics

  • David Castle, University of Guelph

9:30

Science Journalism and the Nutrigenomics Revolution

  • Sally Squires, The Washington Post

  • Susan Okie, New England Journal of Medicine

10:00

Genes, Metabolism, and Behavior: Interacting Networks

  • Ralph Greenspan, Neuroscience Institute

 

Nutrigenomics: Industry’s Perspective

  • Peter Gillies, DuPont

11:00

Break

11:15

Needs and Opportunities in the Food and Agricultural Sciences

  • Joseph Spence, Agricultural Research Service, U.S. Department of Agriculture

Suggested Citation:"Appendix B: Workshop Agenda." Institute of Medicine. 2007. Nutrigenomics and Beyond: Informing the Future: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/11845.
×

 

Nutrigenomics in Public Health: Moving the Field Forward

  • Harvey V. Fineberg, President, Institute of Medicine, The National Academies

12:15 p.m.

Discussion and Next Steps

1:00

Adjourn

Suggested Citation:"Appendix B: Workshop Agenda." Institute of Medicine. 2007. Nutrigenomics and Beyond: Informing the Future: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/11845.
×
Page 65
Suggested Citation:"Appendix B: Workshop Agenda." Institute of Medicine. 2007. Nutrigenomics and Beyond: Informing the Future: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/11845.
×
Page 66
Suggested Citation:"Appendix B: Workshop Agenda." Institute of Medicine. 2007. Nutrigenomics and Beyond: Informing the Future: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/11845.
×
Page 67
Suggested Citation:"Appendix B: Workshop Agenda." Institute of Medicine. 2007. Nutrigenomics and Beyond: Informing the Future: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/11845.
×
Page 68
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The integration of biology, genomics, and health has opened the possibility of applying genomics technology to nutrition. In 2001, scientists associated with the Human Genome Project announced the successful mapping of the reference sequence of the human genome. Since then, a body of information has emerged. Genomics and related areas of research have contributed greatly to efforts to understand the cellular and molecular mechanisms underlying diet-disease relationships. Integration and application of genetic and genomics technology into nutrition research is, therefore, needed to develop nutrition research programs that are aimed at the prevention and control of chronic disease through genomics-based nutritional interventions. Of interest is the integration of relevant computational methods into nutritional genomics research; the enhancement of tools applicable to systems biology; and the effective dissemination of genomics-derived information to scientists, policy makers, and the interested public.

To address these issues, a workshop was held on June 1 and 2, 2006. The workshop included presentations that were structured around three focus sessions: human genetic variation, epigenetics, and systems biology. A fourth session presented discussions on the implications of nutrigenomics for the future of nutrition science research.

Numerous themes emerged from the workshop presentations. First, nutrigenomics is a complex field because it addresses issues related to multigenetic traits that can be modified by a number of nutritional and other environmental factors. Such complexity presents a challenge to the field; and the ensuing research opportunities will require cooperative work among scientific disciplines and across government, academic, and industrial centers, as well as adequate funding, to be realized.

Additionally, the ability to stretch the limits of conventional research methodologies afforded by new genetic and genomic applications at the level of the individual opens the door to a wealth of potential benefits to areas such as disease prevention and wellness, bearing in mind the necessity of ethical safeguards. This potential, however, must be wisely exploited to avoid the pitfalls of overpromising research results and prematurely setting unrealistic expectations for beneficial outcomes. Finally, careful and rigorous research must be employed to optimize outcomes and assure acceptance by the scientific community. In summary, nutrition science is uniquely poised to serve as the crossroads for many disciplines and, using genomics tools, can bring this knowledge together to better understand and address diet-related chronic diseases and molecular responses to dietary factors.

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