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Suggested Citation:"Acronyms." Institute of Medicine. 2010. A National Cancer Clinical Trials System for the 21st Century: Reinvigorating the NCI Cooperative Group Program. Washington, DC: The National Academies Press. doi: 10.17226/12879.
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Acronyms

AACI Association of American Cancer Institutes

AAMC American Association of Medical Colleges

ACOSOG American College of Surgeons Oncology Group

ACRIN American College of Radiology Imaging Network

ACS CAN American Cancer Society Cancer Action Network

AE adverse event

AHRQ Agency for Healthcare Research and Quality

AIPC androgen-independent prostate cancer

ALERT Act 21st Century Cancer Access to Life-Saving Early Detection, Research, and Treatment Act

ALL acute lymphoblastic leukemia

AML acute myeloid leukemia

ARRA American Recovery and Reinvestment Act of 2009

ASCO American Society of Clinical Oncology

BCG bacillus Calmette-Guérin

BICR blinded independent central review

BIG Breast International Group

BRB Biometric Research Branch

BSA Board of Scientific Advisors (National Cancer Institute)

CALGB Cancer and Leukemia Group B

CCG Children’s Cancer Group

CCOP Community Clinical Oncology Program

CCSG Cancer Center Support Grant

Suggested Citation:"Acronyms." Institute of Medicine. 2010. A National Cancer Clinical Trials System for the 21st Century: Reinvigorating the NCI Cooperative Group Program. Washington, DC: The National Academies Press. doi: 10.17226/12879.
×

CER comparative effectiveness research

CHOP cyclophosphamide, doxorubicin, vincristine, and prednisone

CIRB central institutional review board

CLL chronic lymphocytic leukemia

CMS Centers for Medicare & Medicaid Services

COG Children’s Oncology Group

CRADA Cooperative Research and Development Agreement

CRI Clinical Research Initiative (Association of American Cancer Institutes)

CSDD Center for the Study of Drug Development

CT computed tomography

CTAC Clinical Trials Advisory Committee

CTEP Cancer Therapy Evaluation Program

CTMB Clinical Trials Monitoring Branch

CTROC Clinical Trials and Translational Research Operations Committee

CTSA Clinical and Translational Science Awards

CTSU Cancer Trials Support Unit

CTTI Clinical Trials Transformation Initiative

CTU Clinical Trials Unit

CTWG Clinical Trials Working Group

CYP2D6 cytochrome P-450 2D6

DCE-MRI dynamic contrast-enhanced magnetic resonance imaging

DCPC Division of Cancer Prevention and Control

DCTD Division of Cancer Treatment and Diagnosis

DCTDC Division of Cancer Treatment, Diagnosis, and Centers

ECOG Eastern Cooperative Oncology Group

EGFR epidermal growth factor receptor

EMR electronic medical record

EORTC European Organisation for Research and Treatment of Cancer

ER estrogen receptor

ERISA Employee Retirement Income Security Act of 1974

5-FU fluorouracil

18F-FDG fluorine-18 fluorodeoxyglucose

FDA Food and Drug Administration

FDAAA Food and Drug Administration Amendments Act of 2007

FNIH Foundation for the National Institutes of Health

FOLFOX4 oxaliplatin, 5-fluorouracil, and leucovorin

Suggested Citation:"Acronyms." Institute of Medicine. 2010. A National Cancer Clinical Trials System for the 21st Century: Reinvigorating the NCI Cooperative Group Program. Washington, DC: The National Academies Press. doi: 10.17226/12879.
×

FTE full-time equivalent

GIST gastrointestinal stromal tumors

GOG Gynecologic Oncology Group

HER-2 human epidermal growth factor receptor 2

HHS U.S. Department of Health and Human Services

HIPAA Health Insurance Portability and Accountability Act

ICF informed-consent form

IDB Investigational Drug Branch

IDE investigational device exemption

IND investigational new drug

IOM Institute of Medicine

IP intellectual property

IRB institutional review board

I-SPY TRIAL Investigation of Serial studies to Predict Your Therapeutic Response with Imaging And moLecular analysis

KRAS Kirsten ras

LOI letter of intent

MAMS multiarm, multistage (trial design)

MARVEL Marker Validation for Erlotinib in Lung cancer

MINDACT Microarray in Node-negative Disease may Avoid ChemoTherapy

MMRC Multiple Myeloma Research Consortium

MRC Medical Research Council

MRD minimal residual disease

MRI magnetic resonance imaging

NBL neuroblastoma

NCAB National Cancer Advisory Board

NCCF National Children’s Cancer Foundation

NCCN National Comprehensive Cancer Network

NCCTG North Central Cancer Treatment Group

NCD National Coverage Decision

NCI National Cancer Institute

NIH National Institutes of Health

NNCO National Nanotechnology Coordination Office

NSABP National Surgical Adjuvant Breast and Bowel Project

NSCLC non-small-cell lung cancer

Suggested Citation:"Acronyms." Institute of Medicine. 2010. A National Cancer Clinical Trials System for the 21st Century: Reinvigorating the NCI Cooperative Group Program. Washington, DC: The National Academies Press. doi: 10.17226/12879.
×

NSET Nanoscale Science, Engineering, and Technology Subcommittee

OCR Office for Civil Rights (U.S. Department of Health and Human Services)

OEWG Operational Efficiency Working Group

OHRP Office for Human Research Protections (U.S. Department of Health and Human Services)

pCR pathologic complete response

PERCIST PET Response Criteria in Solid Tumors

PET positron emission tomography

Ph+ Philadelphia chromosome positive

POG Pediatric Oncology Group

QIBA Quantitative Imaging Biomarkers Alliance

QOPI Quality Oncology Practice Initiative

RECIST Response Evaluation Criteria in Solid Tumors

RTOG Radiation Therapy Oncology Group

SACHRP Secretary’s Advisory Committee on Human Research Protections

SPECT single-photon emission computed tomography

SPORE Specialized Programs of Research Excellence

STAMPEDE Systemic Therapy in Advancing or Metastatic Prostate Cancer: Evaluation of Drug Efficacy

STPI Science and Technology Policy Institute

SWOG Southwest Oncology Group

TAILORx Trial Assigning IndividuaLized Options for Treatment

TRWG Translational Research Working Group

Tufts CSDD Tufts Center for the Study of Drug Development

US ultrasound

VA U.S. Department of Veterans Affairs

VEGF vascular endothelial growth factor

Suggested Citation:"Acronyms." Institute of Medicine. 2010. A National Cancer Clinical Trials System for the 21st Century: Reinvigorating the NCI Cooperative Group Program. Washington, DC: The National Academies Press. doi: 10.17226/12879.
×
Page 275
Suggested Citation:"Acronyms." Institute of Medicine. 2010. A National Cancer Clinical Trials System for the 21st Century: Reinvigorating the NCI Cooperative Group Program. Washington, DC: The National Academies Press. doi: 10.17226/12879.
×
Page 276
Suggested Citation:"Acronyms." Institute of Medicine. 2010. A National Cancer Clinical Trials System for the 21st Century: Reinvigorating the NCI Cooperative Group Program. Washington, DC: The National Academies Press. doi: 10.17226/12879.
×
Page 277
Suggested Citation:"Acronyms." Institute of Medicine. 2010. A National Cancer Clinical Trials System for the 21st Century: Reinvigorating the NCI Cooperative Group Program. Washington, DC: The National Academies Press. doi: 10.17226/12879.
×
Page 278
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A National Cancer Clinical Trials System for the 21st Century: Reinvigorating the NCI Cooperative Group Program Get This Book
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The National Cancer Institute's (NCI) Clinical Trials Cooperative Group Program has played a key role in developing new and improved cancer therapies. However, the program is falling short of its potential, and the IOM recommends changes that aim to transform the Cooperative Group Program into a dynamic system that efficiently responds to emerging scientific knowledge; involves broad cooperation of stakeholders; and leverages evolving technologies to provide high-quality, practice-changing research.

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