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Enhancing Food Safety: The Role of the Food and Drug Administration (2010)

Chapter: Appendix F: Food Safety Research at Intramural and Extramural U.S. Food and Drug Administration Research Centers, by Topic

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Suggested Citation:"Appendix F: Food Safety Research at Intramural and Extramural U.S. Food and Drug Administration Research Centers, by Topic." Institute of Medicine and National Research Council. 2010. Enhancing Food Safety: The Role of the Food and Drug Administration. Washington, DC: The National Academies Press. doi: 10.17226/12892.
×

Appendix F
Food Safety Research at Intramural and Extramural U.S. Food and Drug Administration Research Centers, by Topic

TABLE F-1 Intramural Research Centers

Topic

Project

Center for Food Safety and Applied Nutrition (CFSAN)

Additives

Development of Methodology to Detect and Quantitate Intermediates and Unsulfonated Impurities in Certifiable Color Additives

 

Use of Migration Models for Indirect Food Additive Approval

Allergens

Approaches to Establish Thresholds for Major Food Allergens and for Gluten in Food

 

The Detection of Food Allergens Using Rapid Immunology– Based Detection Devices

 

Direct Detection, Confirmation, and Measurement of Allergens in Food Matrices

 

Effects of Cleaning on Removal of Allergenic Foods from Food-Contact Surfaces

 

Food Allergen Research

 

Prevalence of Self-Reported Food Allergy in American Adults and Use of Food Labels

Filth and Spoilage

Assessment of Seafood Decomposition with Electronic Sensors

 

Evaluation of the 2-Day Hydrophobic Grid Membrane Filter, Simplate Yeast and Mold Color Indicator, and Petrifilm Dry Dehydratable Film Methods for the Enumeration of Fungi from Foods

 

Filth and Extraneous Materials in Foods

Suggested Citation:"Appendix F: Food Safety Research at Intramural and Extramural U.S. Food and Drug Administration Research Centers, by Topic." Institute of Medicine and National Research Council. 2010. Enhancing Food Safety: The Role of the Food and Drug Administration. Washington, DC: The National Academies Press. doi: 10.17226/12892.
×

Topic

Project

Food Defense: Control

Chemical and Thermal Inactivation of Ricin

Thermal Characterization of Botulinum Neurotoxin Using Scanning Differential Calorimetry

Food Defense: Detection

Counter Terrorism for Proteinaceous Toxins: Ricin, Clostridium botulinum, and Staphylococcal enterotoxin B

Detection of Clostridium botulinum Neurotoxins in Foods

The Detection of Proteinaceous Toxins and Biomarkers of Select Agents Using Multianalyte (Multiplex) and Agent Specific Technologies

Determination of the Characteristics in Foods of Bacillus anthracis in Comparison to Other Bacillus Species

Development of Rapid, Multiplexed Methods for Detection and Confirmation of Protein Toxins and Allergens in Food Using Matrix Assisted Laser Desorption/Ionization and Electrospray Mass Spectrometry

Isolation and Identification of Non-Traditional Pathogens from Food

Foodborne Pathogens: Detection, General

Alternative Molecular Subtyping Methods for Microbial Foodborne Pathogens

The Application of Deoxyribonucleic Acid (DNA) Microarray Technology in Bacterial Identification Using Different Food Matrices and the Detection of DNA Hybridization Constructs Using Infrared Spectroscopy

The Application of Interferometric Biosensor Technology to the Analysis of Food Matrices for Multiple Bacterial and Viral Pathogens, Allergens, and Toxins

Characterization of the Zinc-Containing Metalloprotease Encoded by zpx and Development of a Species-Specific Detection Method for Enterobacter sakazakii

Development and Validation of Methods for Species Identification of Potentially Hazardous Fish Species Based on DNA Bar-Coding

Development of Liquid Chromatography/Mass Spectrometry Protein Profiling as a Tool for Bacterial Differentiation

Diagnostic Methodology for Foodborne Illness (Bacteria and Virus)

Evaluation of Bioluminex Test Methods and Application to the Analysis of Foods

Evaluation of Direct Analysis in Real Time Ionization and Application to the Analysis of Foods and Food Contact Substances

Infrared Detection of Label-Free DNA Hybridization on a Microarray Platform for Use in the Identification of Virulence Genes in Foodborne Microorganisms

Molecular Applications for Identifying Microbial Pathogens in the Post-9/11 Era

Suggested Citation:"Appendix F: Food Safety Research at Intramural and Extramural U.S. Food and Drug Administration Research Centers, by Topic." Institute of Medicine and National Research Council. 2010. Enhancing Food Safety: The Role of the Food and Drug Administration. Washington, DC: The National Academies Press. doi: 10.17226/12892.
×

Topic

Project

 

Prevalence of Pathogens in Imported Product

Pulsed-Field Gel Electrophoresis (PFGE) of Microbial Foodborne Pathogens

Surface Plasmon Resonance Detection of Foodborne Pathogens and Toxins

Use of Gas Chromatography-Flame Ionization Detector and Gas Chromatography-Mass Spectrometry (GC-MS) for Identification and Classification of Foodborne Bacteria and Spores

Foodborne Pathogens: Emerging Pathogens

Genomic Analysis of Cyclopsora cayetenensis and Cryptosporidium spp: Methods Development for Viability and Molecular Epidemiological Applications

Identification and Analyses of Invasion Gene Targets for Use as Diagnostic Probes to Detect Virulent Enterobacter sakazakii

Molecular Characterization of Foodborne Pathogens and the Development of Virulence Factor

Foodborne Pathogens: Foodborne Viruses

Effects of Food Processing on Viruses in Foods

Microarray Based Identification of Foodborne Viruses

Viral Survival During Produce Processing and Storage: Determined by Cellar Infectivity and Real-Time Polymerase Chain Reaction (PCR)

Foodborne Pathogens: Gram-Negative Bacterial Pathogens (E. coli, Salmonella, Shigella, Yersina)

Development of a Method to Enrich and Detect Salmonella enteritidis in Whole Eggs

Ecology and Control of Salmonella Newport on Tomatoes

Genetic and Phenotypic Differentiation of Salmonella enteritidis Strains Derived from Poultry

Genetic Factors Regulating Salmonella Stress Response

Identification of Shigella Species by GC-MS/MS and Two-Dimensional Gas Chromatography-Time of Flight

Modification of Shigella Isolation and Detection Methods

Molecular Characterization of Atypical Strains of Enterohemorrhagic Escherichia coli

Molecular Evolution of Enteric Pathogens

Recurrent Multistate Outbreak of Salmonella Newport Associated with Tomatoes from Contaminated Fields

A Systems Approach to Minimize E. coli O157:H7 Food Safety Hazards Associated with Fresh and Fresh-Cut Leafy Greens

Thermal Resistance of Yersinia Species in Milk and Other Liquids Related to Food Composition

Foodborne Pathogens: L. monocytogenes

Comparative Genomic Analysis of Listeria monocytogenes for Survival in Food Processing Environments

Effect of Solids Levels on the Thermal Resistance of Listeria Species

Suggested Citation:"Appendix F: Food Safety Research at Intramural and Extramural U.S. Food and Drug Administration Research Centers, by Topic." Institute of Medicine and National Research Council. 2010. Enhancing Food Safety: The Role of the Food and Drug Administration. Washington, DC: The National Academies Press. doi: 10.17226/12892.
×

Topic

Project

 

Efficacy of Mitigation Techniques Against Listeria monocytogenes on Seafood and Seafood Processing Surfaces

Growth Modeling and Assessment of Technologies for Pathogen Reduction or Elimination of Listeria monocytogenes

Identification and Characterization of Factors Associated with the Virulence of Listeria monocytogenes Involved in Human Gastroenteritis

Optimization and Validation of Real Time PCR Most Probable Number Enumeration of Foodborne Listeria monocytogenes

Foodborne Pathogens: Processing

Decontamination of Dry Ingredients

Inactivation of Clostridium botulinum Spores Using High Pressure Processing

Post-Harvest Practices to Enhance the Safety of Fresh Tomatoes

Validation of Microwave Pasteurization of Multiple Shell Eggs

Foodborne Pathogens: Risk Assessment

Development of a Risk-Ranking Framework to Evaluate Potential High-Threat Microorganisms, Toxins, and Chemicals in Food

Development of Bacterial Pathogenesis Models Using Ceanorhabditis elegans as Host Organism to Study Bacterial Virulence and Host Defense Factors

Framework for Establishing Extended Shelf-Life Processes Using the Food Safety Objective Approach

Joint U.S. Food and Drug Administration (FDA)/Health Canada Public Health Risk Assessment of Listeria monocytogenes in Cheese

Risk Assessment for the Public Health Impact of Highly Pathogenic Avian Influenza Virus in Poultry Meat, Shell Eggs, and Egg Products

Risk Assessment to Determine Potential of Chronic Wasting Disease in Infected Cervids as a Human Health Risk

Foodborne Pathogens: Seafood Toxins

Biomarkers of Neurotoxic Shellfish Poisoning

Ciguatera Fish Poisoning

Detection Methods for Paralytic Shellfish Poisoning Toxins

Development of Conjugates of Saxitoxins for the Production of Antibodies

An Intervention Analysis for the Reduction of Exposure to Methylmercury from the Consumption of Seafood by Women of Child-Bearing Age

Mussel-Associated Azaspiracid Intoxication in the United States

Neurotoxic Shellfish Poisoning

Non-Traditional Vectors for Paralytic Shellfish Poisoning

Suggested Citation:"Appendix F: Food Safety Research at Intramural and Extramural U.S. Food and Drug Administration Research Centers, by Topic." Institute of Medicine and National Research Council. 2010. Enhancing Food Safety: The Role of the Food and Drug Administration. Washington, DC: The National Academies Press. doi: 10.17226/12892.
×

Topic

Project

 

Paralytic Shellfish Poisoning: Link Between Surface Algal Blooms and Deep Water Shellfish Toxicity in Federal Waters

Foodborne Pathogens: Surveys

Indicator Microorganisms and Viruses in Shellfish in Harvest Waters

Microbiological Survey of Raw Oysters Collected at Retail Across the United States

Survey of U.S. Raw Milk Supply for Pathogens

Toxicology: Detection

Analysis of Total Mercury in Foods by Compton Suppression Instrumental Neutron Activation Analysis

Determination of the Thyroid-Interactive Anions Iodide, Perchlorate, and Thiocyanate in Food

Development of Tuna Reference Material for Toxic Elements

Impact of Processing on Detection of Melamine and Cyanuric Acid

Methodology for Determination of Volatile Contaminants in Foods

Two-Dimensional Gas Chromatography and Time-of-Flight Mass Spectrometry for the Determination of Pesticides and Persistent Organic Pollutants in Foods

Validating the Predictive Performance of Caenorhabditis elegans as an Animal Model for Toxicity Testing

Toxicology: Mechanisms

Cellular and Cytokine Biomarkers for Infectious and Inflammatory Models

Denaturation/Renaturation Kinetics of Staphylococcal Enterotoxin in Acidic Foods

Evaluation of the Mass Transfer Properties of Perfluoro Chemicals from Paper Food Packaging

Hepatotoxicity—Role of Gender, Species and Inflammation on In Vitro and In Vivo Biomarkers of Liver Toxicity

Interaction of Combined Exposure to the Microbial Toxin Lipopolysaccharide (and Deficient or Graded Dietary Vitamin D Level

Toxicology: Monitoring

Acrylamide Testing at CFSAN: Exploratory Survey Results

Aquaculture Drugs and Chemicals

FDA Toxicity Databases and Real-Time Data Entry

FDA’s Total Diet Study: Dietary Intake of Perchlorate and Iodine

Health Care Provider Survey—re the Methylmercury Advisory

Suggested Citation:"Appendix F: Food Safety Research at Intramural and Extramural U.S. Food and Drug Administration Research Centers, by Topic." Institute of Medicine and National Research Council. 2010. Enhancing Food Safety: The Role of the Food and Drug Administration. Washington, DC: The National Academies Press. doi: 10.17226/12892.
×

Topic

Project

Center for Veterinary Medicine (CVM)

Animal Feed Safety

Antimicrobial Susceptibility of Native Enterococcus faecium from Chickens Given Feed Containing Virginiamycin

Detecting Animal Tissues in Feed and Feed Ingredients

Evaluation of Two Commercial Lateral-Flow Test Kits That Detect Animal Proteins in Finished Animal Feed

Validation of a PCR-Based Method for the Detection of Various Rendered Materials in Feedstuffs Using a Forensic DNA Extraction Kit

Compliance*

Develop Needed Enforcement Methods for Drug Residues

Evaluate Screening Test Performance

Perform Method Trials to Determine Drug Residues from Unapproved Uses

Use Tissue-Fluid Correlations to Predict Drug Residue Levels in Edible Tissues from Food-Producing Animals

Premarket Drug Review: Antimicrobial Resistance Mechanisms

The Clonal Spread of Multidrug-Resistant Non-Typhi Salmonella Serotypes

Determine Microbial Ecology of Antibiotic Resistance Development and Dissemination in the Food Animal Production Environment

Genetic Diversity and Antimicrobial Susceptibility Profiles Among Staphylococcus aureus Isolated from Bovine Mastitis

Interrogate Salmonella Diversity Using a Novel 35 Genome Salmonella Species Microarray—A Critical Path Study

Use Molecular and Biochemical Methods to Determine the Animal Origin of Foodborne Bacterial Pathogens

Premarket Drug Review: Microbiological Methods

Broth Microdilution Susceptibility Testing of Campylobacter jejuni and the Determination of Quality Control Ranges for 14 Antimicrobial Agents

Conduct Molecular Characterization of Foodborne Bacterial Pathogens Isolated from Animals and Retail Meats by Microarray Technology

Develop Antimicrobial Susceptibility Testing Methods and Interpretive Criteria for Aquatic Animal Microflora

Develop Standardized In Vitro Antimicrobial Susceptibility Testing Methods for Bacterial Pathogens

Salmonella Resistant to Extended-Spectrum Cephalosporins: Prevalence and Epidemiology

Suggested Citation:"Appendix F: Food Safety Research at Intramural and Extramural U.S. Food and Drug Administration Research Centers, by Topic." Institute of Medicine and National Research Council. 2010. Enhancing Food Safety: The Role of the Food and Drug Administration. Washington, DC: The National Academies Press. doi: 10.17226/12892.
×

Topic

Project

Postmarket Approval and Monitoring: Analysis of Survey Data

Characterize Antimicrobial Resistance Among Bacteria Isolated from Retail Meats

Characterize Antimicrobial Resistance Among Historical Isolates of Foodborne Pathogens

Characterize Antimicrobial Resistance Mechanisms of Animal Bacterial Pathogens

Determine the Prevalence of Pathogenic Escherichia coli Recovered from National Antimicrobial Resistance Monitoring System (NARMS) Retail Meats

DNA Fingerprinting of Foodborne Pathogens by PFGE (in conjunction with PulseNet)

Genotyping of Campylobacter coli Isolated from Humans and Retail Meats Using Multilocus Sequence Typing and PFGE

Molecular Serotyping of Salmonella spp by Using the Luminex Multianalyte Profiling (xMAP) Technology

Survey Susceptibility of Foodborne Pathogens from Humans, Food, and Animals in Mexico

Use of Tissue-Fluid Correlations to Estimate Gentamicin Residues in Kidney Tissue of Holstein Steers

Postmarket Approval and Monitoring: Survey Programs

Center for Veterinary Medicine (CVM) Participation in the NARMS Program

CVM Participation in PulseNet

Targeted Surveys as Needed

Veterinary Drug Residues

National Center for Toxicological Research (NCTR)

Antimicrobial Resistance

Antimicrobial Resistance Genetics of “Emerging” Salmonella enterica Serovar Javiana Phenotypes Involved in Clinical and Food-Related Outbreaks

Beta-Lactamase Resistance in enterococci

Heteroresistance to Vancomycin and Novel Point Mutations in Tn1546 of Enterococcus faecium ATCC 51559

Molecular Characterization of Multidrug-Resistant Enterococcus spp from Poultry and Dairy Farms: Detection of Virulence and Vancomycin Resistance Gene Markers by PCR

Substitutions of Amino Acids in Alpha-Helix-4 of Gyrase A Confer Fluoroquinolone Resistance on Clostridium perfringens

Suggested Citation:"Appendix F: Food Safety Research at Intramural and Extramural U.S. Food and Drug Administration Research Centers, by Topic." Institute of Medicine and National Research Council. 2010. Enhancing Food Safety: The Role of the Food and Drug Administration. Washington, DC: The National Academies Press. doi: 10.17226/12892.
×

Topic

Project

Methods Development

Biostatistical Modeling for Food Protection Plan

Development of Public Toxicogenomics Software for Microarray Data Management and Analysis

Evaluation of Certain Food Additives and Contaminants

Genotoxic Effects of Acrylamide and Glycidamide in Mouse Lymphoma Cells

In Vitro Antimicrobial Susceptibility, Genetic Diversity and Prevalence of Uridine Diphosphate-Glucose 4-Epimerase Gene in Campylobacter coli and Campylobacter jejuni from Turkey Production Facilities

Innovative, Static, and Dynamic Chemical Sensors for Food Safety—Litmus Cooperative Research and Development Agreement

Integrating Time-Course Microarray Gene Expression Profiles with Cytotoxicity for Identification of Biomarkers in Primary Rat Hepatocytes Exposed to Cadmium

Isolation and Characterization of Tetracycline-Resistant Citrobacter spp from Catfish

Mold2, Molecular Descriptors from Two-Dimensional Structures for Chemoinformatics and Toxicoinformatics

Molecular Characterization of Salmonella spp and Vibrio spp Isolated from Seafood and Development of Microarray Detection Method

Molecular Typing Methodologies for Microbial Source Tracking and Epidemiological Investigations of Gram-Negative Bacterial Foodborne Pathogens

Physiologically-Based Pharmacokinetic/Pharmacodynamic Model for Acrylamide and Its Metabolites in Mice, Rats, and Humans

Rapid Bacterial Identification with Subspecies-Level Specificity

Real-Time PCR Assays for Ricin and Related Potential Bioterrorism Agents in Foods

The Survivability of Bacillus anthracis (Sterne Strain) in Processed Liquid Eggs

Other

Chemical Inactivation of Protein Toxins on Food Contact Surfaces

Effect of Egg White Addition to Milk and Ground Beef on the Survival of Sterne Strain of Bacillus anthracis, Salmonella enterococci, and Staphylococci at Different Temperatures

Laboratory Studies in Melamine and Cyanuric Acid Biochemical Toxicology

Mechanistic Evaluation of the Induction of Lymphoproliferation and Apoptosis Inhibition by Probiotic Bacteria in Mice Infected with Salmonella enterica

Suggested Citation:"Appendix F: Food Safety Research at Intramural and Extramural U.S. Food and Drug Administration Research Centers, by Topic." Institute of Medicine and National Research Council. 2010. Enhancing Food Safety: The Role of the Food and Drug Administration. Washington, DC: The National Academies Press. doi: 10.17226/12892.
×

Topic

Project

Risk-Based Research

Anaerobic Metabolism of 1-Amino-2-Naphthol-Based Azo Dyes (Sudan Dyes) by Human Intestinal Microflora

Approaches in the Safety Evaluations of Veterinary Antimicrobial Agents in Food to Determine the Effects on the Human Intestinal Microflora

Identification and Characterization of Class 1 Integron Resistance Gene Cassettes Among Salmonella Strains Isolated from Imported Seafood

Influence of Erythromycin A on the Microbial Populations in Aquaculture Sediment Microcosms

Surveillance

Prevalence and Characterization of Salmonella enterica Serovar Weltevreden from Imported Seafood

Probiotic Bacteria Are Antagonistic to Salmonella enterica and Campylobacter jejuni and Influence Host Lymphocyte Responses in Human Microbiota-Associated Immunodeficient and Immunocompetent Mice

Office of Regulatory Affairs (ORA)

Food Science and Technology

Liquid Chromatographic Analysis of Vitamin B6 in Reconstituted Infant Formula: Collaborative Study

Potential Use of DNA Barcodes in Regulatory Science: Applications of the Regulatory Fish Encyclopedia

Foodborne Pathogens: General

Molecular Confirmation of Oyster as the Vector for Hepatitis A in a 2005 Multistate Outbreak

Recovery of Mycobacterium bovis from Soft Fresh Cheese Originating in Mexico

Foodborne Pathogens: Gram-Negative Bacterial Pathogens (Campylobacter, E. coli, Salmonella, Shigella, Yersina)

Comparison of Salmonella enterica Serovar Heidelberg Susceptibility Testing Results

*Compliance functions focus on methods development and validation, which includes incursion services as needed.

Suggested Citation:"Appendix F: Food Safety Research at Intramural and Extramural U.S. Food and Drug Administration Research Centers, by Topic." Institute of Medicine and National Research Council. 2010. Enhancing Food Safety: The Role of the Food and Drug Administration. Washington, DC: The National Academies Press. doi: 10.17226/12892.
×

TABLE F-2 Extramural Research Centers

Topic

Project

Joint Institute for Food Safety and Applied Nutrition (University of Maryland)

Additives

Predicting Exposure Estimates: Experimental Food Additive Partitioning Studies and Model Development

Filth and Spoilage

Moulds and Yeasts in Fruit Salads and Fruit Juices

Food Defense: Control

Studying Nisin and Sublancin to Strategize Protection of U.S. Food Supply from Bioterrorism

Foodborne Pathogens: General

Enzymatic Degradation of Prion Surrogate Proteins

Plant-Derived Vaccines Against Diarrheal Diseases

Public Health Impact and Cost-Effectiveness of Implementing Good Agricultural Practices in Tomato Farming

Foodborne Pathogens: Gram-Negative Bacterial Pathogens (Campylobacter, E. coli, Salmonella, Shigella, Yersina)

Campylobacter-Induced Interleukin-8 Secretion in Polarized Human Intestinal Epithelial Cells Requires Campylobacter-Secreted Cytolethal Distending Toxin- and Toll-Like Receptor-Mediated Activation of NF-B

Detecting and Identifying Shigella in Foods

Reducing and Controlling Salmonella and E. coli in Crops

Role of Efflux Pumps and Topoisomerase Mutations in Fluoroquinolone Resistance in Campylobacter jejuni and Campylobacter coli

Foodborne Pathogens: Processing

Survival of Enterobacter sakazakii in a Dehydrated Powdered Infant Formula

Risk-Based Research

Emotion Regarding a Food Crisis and Predicting Consumers’ Hesitancy to Eat the Food After the Crisis

Evaluation of the ALERT (Assure, Look, Employees, Reports, Threat) Campaign

Impact on Audience Attitudes and Behaviors of Risk Messages about Act of Bioterrorism on U.S. Food Supply

Toxicology: Detection

Characterizing and Predicting Drug Residues in Fish

National Center for Food Safety and Technolog (Illinois Institute of Technology)

Allergens

Cleaning and Other Control and Validation Strategies to Prevent Allergen Cross-Contact in Food-Processing Operations—A Review

Purification, Crystallization, and Preliminary X-Ray Characterization of Amandin, A Major Allergen in Almonds (Prunus dulcis)

Suggested Citation:"Appendix F: Food Safety Research at Intramural and Extramural U.S. Food and Drug Administration Research Centers, by Topic." Institute of Medicine and National Research Council. 2010. Enhancing Food Safety: The Role of the Food and Drug Administration. Washington, DC: The National Academies Press. doi: 10.17226/12892.
×

Topic

Project

Filth and Spoilage

Factors Affecting Mycotoxin Production in Fruits

Minimum Leak Size Determination, Under Laboratory and Commercial Conditions, for Bacterial Entry into Polymeric Trays Used for Shelf-Stable Food Packaging

Stability of Picrotoxin During Yogurt Manufacture and Storage

Food Defense: Detection

Detection and Decontamination Methods for Food Defense

Foodborne Pathogens: Detection, General

Rapid Tests for Pathogenic Microbes in Food-Producing Animals

Foodborne Pathogens: Foodborne Viruses

Inactivation of Hepatitis A Virus, Poliovirus and a Norovirus Surrogate by High-Pressure Processing

Foodborne Pathogens: L. monocytogenes

Multi-Virulence-Locus Sequence Typing Identifies Single Nucleotide Polymorphisms Which Differentiate Epidemic Clones and Outbreak Strains of Listeria monocytogenes

Foodborne Pathogens: Processing

Modeling the Inactivation of Bacterial Spores

New Kinetic Models for Inactivation of Bacterial Spores

Western Institute for Food Safety and Security (WIFSS, University of California, Davis)

Foodborne Pathogens: General

U.S. Food and Drug Administration Rapid Response Teams (to Enhance, Complement, Develop, and Improve State Manufactured Food Protection Regulatory and Surveillance Programs)

Food Safety Risks and Mitigation Strategies for Feral Swine (Sus scrofa) Near Agriculture Fields

Foodborne Pathogens: Gram-Negative Bacterial Pathogens (E. coli, Salmonella, Shigella, Yersina)

Escherichia coli O157:H7 in Feral Swine Near Spinach Fields and Cattle, Central California Coast

Incidence and Tracking of Escherichia coli O157:H7 in a Major Produce Production Region in California

A Multi-State Outbreak of Escherichia coli O157:H7 Linked to Consumption of Beef Tacos at a Fast-Food Restaurant Chain

 

Salmonella in Almonds

Funded by WIFSS

Foodborne Pathogens: General

Attachment, Uptake, Dissemination and Inactivation of Foodborne Enteric Caliciviruses in Vegetables

Fresh Express—Determining the Environmental Factors Contributing to the Extended Survival or Regrowth of Foodborne Pathogens in Composting Systems

Suggested Citation:"Appendix F: Food Safety Research at Intramural and Extramural U.S. Food and Drug Administration Research Centers, by Topic." Institute of Medicine and National Research Council. 2010. Enhancing Food Safety: The Role of the Food and Drug Administration. Washington, DC: The National Academies Press. doi: 10.17226/12892.
×

Topic

Project

 

Survival and Transmission of Pathogenic Viruses in an Agricultural Environment

Foodborne Pathogens: Gram-Negative Bacterial Pathogens (E. coli, Salmonella, Shigella, Yersina)

Ecology and Epidemiology of E. coli O157:H7 in Fresh Produce Production Regions of the Central California Coast

Effect of Wilting and Tissue Infiltration on the Behavior of E. coli O157:H7 on Leaf Lettuce Directly After Harvest

Evaluation of Growth Kinetics of E. coli O157:H7 on Bagged Spinach, Crisp Head Lettuce, and Romaine Lettuce in Relation to Consumption Decisions Based on Visual Quality and Off-Odors

Infiltration of Edible Plants by E. coli O157:H7

Suggested Citation:"Appendix F: Food Safety Research at Intramural and Extramural U.S. Food and Drug Administration Research Centers, by Topic." Institute of Medicine and National Research Council. 2010. Enhancing Food Safety: The Role of the Food and Drug Administration. Washington, DC: The National Academies Press. doi: 10.17226/12892.
×
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Suggested Citation:"Appendix F: Food Safety Research at Intramural and Extramural U.S. Food and Drug Administration Research Centers, by Topic." Institute of Medicine and National Research Council. 2010. Enhancing Food Safety: The Role of the Food and Drug Administration. Washington, DC: The National Academies Press. doi: 10.17226/12892.
×
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Suggested Citation:"Appendix F: Food Safety Research at Intramural and Extramural U.S. Food and Drug Administration Research Centers, by Topic." Institute of Medicine and National Research Council. 2010. Enhancing Food Safety: The Role of the Food and Drug Administration. Washington, DC: The National Academies Press. doi: 10.17226/12892.
×
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Suggested Citation:"Appendix F: Food Safety Research at Intramural and Extramural U.S. Food and Drug Administration Research Centers, by Topic." Institute of Medicine and National Research Council. 2010. Enhancing Food Safety: The Role of the Food and Drug Administration. Washington, DC: The National Academies Press. doi: 10.17226/12892.
×
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Suggested Citation:"Appendix F: Food Safety Research at Intramural and Extramural U.S. Food and Drug Administration Research Centers, by Topic." Institute of Medicine and National Research Council. 2010. Enhancing Food Safety: The Role of the Food and Drug Administration. Washington, DC: The National Academies Press. doi: 10.17226/12892.
×
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Suggested Citation:"Appendix F: Food Safety Research at Intramural and Extramural U.S. Food and Drug Administration Research Centers, by Topic." Institute of Medicine and National Research Council. 2010. Enhancing Food Safety: The Role of the Food and Drug Administration. Washington, DC: The National Academies Press. doi: 10.17226/12892.
×
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Suggested Citation:"Appendix F: Food Safety Research at Intramural and Extramural U.S. Food and Drug Administration Research Centers, by Topic." Institute of Medicine and National Research Council. 2010. Enhancing Food Safety: The Role of the Food and Drug Administration. Washington, DC: The National Academies Press. doi: 10.17226/12892.
×
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Suggested Citation:"Appendix F: Food Safety Research at Intramural and Extramural U.S. Food and Drug Administration Research Centers, by Topic." Institute of Medicine and National Research Council. 2010. Enhancing Food Safety: The Role of the Food and Drug Administration. Washington, DC: The National Academies Press. doi: 10.17226/12892.
×
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Suggested Citation:"Appendix F: Food Safety Research at Intramural and Extramural U.S. Food and Drug Administration Research Centers, by Topic." Institute of Medicine and National Research Council. 2010. Enhancing Food Safety: The Role of the Food and Drug Administration. Washington, DC: The National Academies Press. doi: 10.17226/12892.
×
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Suggested Citation:"Appendix F: Food Safety Research at Intramural and Extramural U.S. Food and Drug Administration Research Centers, by Topic." Institute of Medicine and National Research Council. 2010. Enhancing Food Safety: The Role of the Food and Drug Administration. Washington, DC: The National Academies Press. doi: 10.17226/12892.
×
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Suggested Citation:"Appendix F: Food Safety Research at Intramural and Extramural U.S. Food and Drug Administration Research Centers, by Topic." Institute of Medicine and National Research Council. 2010. Enhancing Food Safety: The Role of the Food and Drug Administration. Washington, DC: The National Academies Press. doi: 10.17226/12892.
×
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Suggested Citation:"Appendix F: Food Safety Research at Intramural and Extramural U.S. Food and Drug Administration Research Centers, by Topic." Institute of Medicine and National Research Council. 2010. Enhancing Food Safety: The Role of the Food and Drug Administration. Washington, DC: The National Academies Press. doi: 10.17226/12892.
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Enhancing Food Safety: The Role of the Food and Drug Administration Get This Book
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Recent outbreaks of illnesses traced to contaminated sprouts and lettuce illustrate the holes that exist in the system for monitoring problems and preventing foodborne diseases. Although it is not solely responsible for ensuring the safety of the nation's food supply, the U.S. Food and Drug Administration (FDA) oversees monitoring and intervention for 80 percent of the food supply. The U.S. Food and Drug Administration's abilities to discover potential threats to food safety and prevent outbreaks of foodborne illness are hampered by impediments to efficient use of its limited resources and a piecemeal approach to gathering and using information on risks. Enhancing Food Safety: The Role of the Food and Drug Administration, a new book from the Institute of Medicine and the National Research Council, responds to a congressional request for recommendations on how to close gaps in FDA's food safety systems.

Enhancing Food Safety begins with a brief review of the Food Protection Plan (FPP), FDA's food safety philosophy developed in 2007. The lack of sufficient detail and specific strategies in the FPP renders it ineffectual. The book stresses the need for FPP to evolve and be supported by the type of strategic planning described in these pages. It also explores the development and implementation of a stronger, more effective food safety system built on a risk-based approach to food safety management. Conclusions and recommendations include adopting a risk-based decision-making approach to food safety; creating a data surveillance and research infrastructure; integrating federal, state, and local government food safety programs; enhancing efficiency of inspections; and more.

Although food safety is the responsibility of everyone, from producers to consumers, the FDA and other regulatory agencies have an essential role. In many instances, the FDA must carry out this responsibility against a backdrop of multiple stakeholder interests, inadequate resources, and competing priorities. Of interest to the food production industry, consumer advocacy groups, health care professionals, and others, Enhancing Food Safety provides the FDA and Congress with a course of action that will enable the agency to become more efficient and effective in carrying out its food safety mission in a rapidly changing world.

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