Acronyms
Akt protein kinase B
ALS amyotrophic lateral sclerosis
C-Path Critical Path Institute
caBIG cancer Biomedical Informatics Grid
CEO chief executive officer
CERN European Organization for Nuclear Research
CMS Centers for Medicare & Medicaid Services
EBI European Bioinformatics Institute
EMEA European Medicines Agency
FDA Food and Drug Administration
FDG-PET flurodeoxyglucose-positron emission tomography
FNIH Foundation for the National Institutes of Health
I-SPY 2 TRIAL Inspection of Serial studies to Predict Your Therapeutic Response with Imaging And moLecular analysis 2
IGFR insulin-like growth factor receptor
IMI Innovative Medicines Initiative
IND investigational new drug
IP intellectual property
IRB institutional review board
IT information technology
MEK mitogen-activated protein kinase 1
MIT Massachusetts Institute of Technology
MMRF Multiple Myeloma Research Foundation
MRF Myelin Repair Foundation
NCI National Cancer Institute
NHGRI National Human Genome Research Institute
NIH National Institutes of Health
NME new molecular entity
OBQI Oncology Biomarker Qualification Initiative
OSDD Open Source Drug Discovery
PI3K phosphatidylinositol-3 kinase
PMA premarket approval
R&D research and development
SEMATECH SEmiconductor MAnufacturing TECHnology
START Standard Terms of Agreement for Research Trial
TCGA The Cancer Genome Atlas
UCSF University of California–San Francisco