National Academies Press: OpenBook
Suggested Citation:"Front Matter." Institute of Medicine. 2015. Emerging Viral Diseases: The One Health Connection: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/18975.
×

EMERGING VIRAL DISEASES

THE ONE HEALTH CONNECTION


Workshop Summary

Eileen R. Choffnes and Alison Mack, Rapporteurs

Forum on Microbial Threats

Board on Global Health

INSTITUTE OF MEDICINE
              OF THE NATIONAL ACADEMIES

THE NATIONAL ACADEMIES PRESS

Washington, D.C.

www.nap.edu

Suggested Citation:"Front Matter." Institute of Medicine. 2015. Emerging Viral Diseases: The One Health Connection: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/18975.
×

THE NATIONAL ACADEMIES PRESS     500 Fifth Street, NW     Washington, DC 20001

NOTICE: The workshop that is the subject of this workshop summary was approved by the Governing Board of the National Research Council, whose members are drawn from the councils of the National Academy of Sciences, the National Academy of Engineering, and the Institute of Medicine.

Financial support for this activity was provided by the U.S. Department of Health and Human Services: National Institutes of Health, National Institute of Allergy and Infectious Diseases, Centers for Disease Control and Prevention, and the Food and Drug Administration; U.S. Department of Defense: Armed Forces Health Surveillance Center, and U.S. Army Medical Research and Materiel Command; U.S. Department of Justice: Federal Bureau of Investigation; U.S. Department of Veterans Affairs; U.S. Department of Homeland Security; U.S. Agency for International Development; Uniformed Services University of the Health Sciences; Alfred P. Sloan Foundation; American Society for Microbiology; Infectious Diseases Society of America; Johnson & Johnson; Merck Company Foundation; and sanofi pasteur. The views presented in this publication do not necessarily reflect the views of the organizations or agencies that provided support for this activity.

International Standard Book Number-13: 978-0-309-31397-1
International Standard Book Number-10: 0-309-31397-X

Additional copies of this workshop summary are available for sale from the National Academies Press, 500 Fifth Street, NW, Keck 360, Washington, DC 20001; (800) 624-6242 or (202) 334-3313; http://www.nap.edu.

For more information about the Institute of Medicine, visit the IOM home page at: www.iom.edu.

Copyright 2015 by the National Academy of Sciences. All rights reserved.

Printed in the United States of America

The serpent has been a symbol of long life, healing, and knowledge among almost all cultures and religions since the beginning of recorded history. The serpent adopted as a logotype by the Institute of Medicine is a relief carving from ancient Greece, now held by the Staatliche Museen in Berlin.

Cover image: Global hotspot map of emerging infectious diseases (EIDs). This map illustrates the relative risk of a zoonotic emerging infectious disease of wildlife origin spilling over into the human population. It was produced by analyzing with logistic regression the presence/absence of all known wildlife-origin EIDs since 1940 against a series of known drivers, including human population density, change in human population density, and wildlife diversity (mammalian species richness), gridded at 1km2 resolution, and corrected for reporting bias by including a measure of the global distribution of infectious disease researchers. Map produced by EcoHealth Alliance and research funded by USAID-EPT PREDICT.

Suggested citation: IOM (Institute of Medicine). 2015. Emerging Viral Diseases: The One Health Connection. Washington, DC: The National Academies Press.

Suggested Citation:"Front Matter." Institute of Medicine. 2015. Emerging Viral Diseases: The One Health Connection: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/18975.
×

Knowing is not enough; we must apply.
Willing is not enough; we must do.
”      

                                                —Goethe

image

INSTITUTE OF MEDICINE
              OF THE NATIONAL ACADEMIES

Advising the Nation. Improving Health.

Suggested Citation:"Front Matter." Institute of Medicine. 2015. Emerging Viral Diseases: The One Health Connection: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/18975.
×

THE NATIONAL ACADEMIES

Advisers to the Nation on Science, Engineering, and Medicine

The National Academy of Sciences is a private, nonprofit, self-perpetuating society of distinguished scholars engaged in scientific and engineering research, dedicated to the furtherance of science and technology and to their use for the general welfare. Upon the authority of the charter granted to it by the Congress in 1863, the Academy has a mandate that requires it to advise the federal government on scientific and technical matters. Dr. Ralph J. Cicerone is president of the National Academy of Sciences.

The National Academy of Engineering was established in 1964, under the charter of the National Academy of Sciences, as a parallel organization of outstanding engineers. It is autonomous in its administration and in the selection of its members, sharing with the National Academy of Sciences the responsibility for advising the federal government. The National Academy of Engineering also sponsors engineering programs aimed at meeting national needs, encourages education and research, and recognizes the superior achievements of engineers. Dr. C. D. Mote, Jr., is president of the National Academy of Engineering.

The Institute of Medicine was established in 1970 by the National Academy of Sciences to secure the services of eminent members of appropriate professions in the examination of policy matters pertaining to the health of the public. The Institute acts under the responsibility given to the National Academy of Sciences by its congressional charter to be an adviser to the federal government and, upon its own initiative, to identify issues of medical care, research, and education. Dr. Victor J. Dzau is president of the Institute of Medicine.

The National Research Council was organized by the National Academy of Sciences in 1916 to associate the broad community of science and technology with the Academy’s purposes of furthering knowledge and advising the federal government. Functioning in accordance with general policies determined by the Academy, the Council has become the principal operating agency of both the National Academy of Sciences and the National Academy of Engineering in providing services to the government, the public, and the scientific and engineering communities. The Council is administered jointly by both Academies and the Institute of Medicine. Dr. Ralph J. Cicerone and Dr. C. D. Mote, Jr., are chair and vice chair, respectively, of the National Research Council.

www.national-academies.org

Suggested Citation:"Front Matter." Institute of Medicine. 2015. Emerging Viral Diseases: The One Health Connection: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/18975.
×

PLANNING COMMITTEE FOR THE WORKSHOP
ON EMERGING VIRAL DISEASES1

PETER DASZAK, EcoHealth Alliance, New York, New York

JEFFREY DUCHIN, Public Health–Seattle & King County, Seattle, Washington

CAROLE HEILMAN, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland

JAMES M. HUGHES, Global Infectious Diseases Program, Emory University, Atlanta, Georgia

RIMA KHABBAZ, Centers for Disease Control and Prevention, Atlanta, Georgia

DAVID SWAYNE, Agricultural Research Service, U.S. Department of Agriculture, Athens, Georgia

JOHN WATSON, Public Health England, London, United Kingdom

_______________

1 Institute of Medicine planning committees are solely responsible for organizing the workshop, identifying topics, and choosing speakers. The responsibility for the published workshop summary rests solely with the workshop rapporteurs and the institution.

Suggested Citation:"Front Matter." Institute of Medicine. 2015. Emerging Viral Diseases: The One Health Connection: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/18975.
×

FORUM ON MICROBIAL THREATS1

DAVID A. RELMAN (Chair), Stanford University, and Veterans Affairs Palo Alto Health Care System, Palo Alto, California

JAMES M. HUGHES (Vice chair), Global Infectious Diseases Program, Emory University, Atlanta, Georgia

LONNIE J. KING (Vice chair), Ohio State University, Columbus, Ohio

KEVIN ANDERSON, Biological and Chemical Defense Division, Science and Technology Directorate, U.S. Department of Homeland Security, Washington, DC

ENRIQUETA C. BOND, Burroughs Wellcome Fund (Emeritus), QE Philanthropic Advisors, Marshall, Virginia

ROGER G. BREEZE, Lawrence Livermore National Laboratory, Livermore, California

ARTURO CASADEVALL, Albert Einstein College of Medicine, Bronx, New York

ANDREW CLEMENTS, U.S. Agency for International Development, Washington, DC

PETER DASZAK, EcoHealth Alliance, New York, New York

JEFFREY S. DUCHIN, Public Health–Seattle and King County, Seattle, Washington

JONATHAN EISEN,2 Genome Center, University of California, Davis, California

MARK B. FEINBERG, Merck Vaccine Division, Merck & Co., Inc., West Point, Pennsylvania

AARON M. FIROVED,3 Office of Health Affairs, U.S. Department of Homeland Security, Washington, DC

JACQUELINE FLETCHER, Oklahoma State University, Stillwater, Oklahoma

CLAIRE FRASER, Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland

JESSE L. GOODMAN,4 Georgetown University, Washington, DC

EDUARDO GOTUZZO, Instituto de Medicina Tropical–Alexander von Humboldt, Universidad Peruaña Cayetano Heredia, Lima, Peru

CAROLE A. HEILMAN, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland

DAVID L. HEYMANN, Public Health England, London, United Kingdom

PHILIP HOSBACH, sanofi pasteur, Swiftwater, Pennsylvania

_______________

1 Institute of Medicine forums and roundtables do not issue, review, or approve individual documents. The responsibility for the published workshop summary rests with the workshop rapporteurs and the institution.

2 Forum member until July 31, 2014.

3 Forum member since November 14, 2014.

4 Forum member since August 7, 2014.

Suggested Citation:"Front Matter." Institute of Medicine. 2015. Emerging Viral Diseases: The One Health Connection: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/18975.
×

STEPHEN ALBERT JOHNSTON, Arizona BioDesign Institute, Arizona State University, Tempe, Arizona

GERALD T. KEUSCH, Boston University School of Medicine and Boston University School of Public Health, Boston, Massachusetts

RIMA F. KHABBAZ, Centers for Disease Control and Prevention, Atlanta, Georgia

MARK KORTEPETER, Uniformed Services University of the Health Sciences, Bethesda, Maryland

STANLEY M. LEMON, University of North Carolina, Chapel Hill, North Carolina

MARGARET McFALL-NGAI, University of Wisconsin, Madison, Wisconsin

EDWARD McSWEEGAN, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland

PAULA J. OLSIEWSKI, Alfred P. Sloan Foundation, New York, New York

STEPHEN OSTROFF, Food and Drug Administration, Silver Spring, Maryland

JULIE PAVLIN, Armed Forces Health Surveillance Center, Silver Spring, Maryland

GEORGE POSTE, Complex Adaptive Systems Initiative, Arizona State University, SkySong, Scottsdale, Arizona

DAVID RIZZO, Department of Plant Pathology, University of California, Davis, California

GARY A. ROSELLE, Veterans Health Administration, Department of Veterans Affairs, Cincinnati, Ohio

KEVIN RUSSELL, Armed Forces Health Surveillance Center, Silver Spring, Maryland

JANET SHOEMAKER, American Society for Microbiology, Washington, DC

JAY P. SIEGEL, Johnson & Johnson, Radnor, Pennsylvania

P. FREDERICK SPARLING,5 University of North Carolina, Chapel Hill, North Carolina

MARY E. WILSON, Harvard School of Public Health, Harvard University, Boston, Massachusetts

EDWARD H. YOU, Federal Bureau of Investigation, Washington, DC

IOM Staff

EILEEN CHOFFNES, Scholar and Director

KATHERINE McCLURE,6 Associate Program Officer

REBEKAH HUTTON,7 Research Associate

PRIYANKA NALAMADA, Senior Program Assistant

JOANNA ROBERTS,8 Senior Program Assistant (Temp)

_______________

5 Forum member until June 30, 2014.

6 Staff member until December 31, 2014.

7 Staff member until November 14, 2015.

8 Staff member until March 31, 2014.

Page viii Cite
Suggested Citation:"Front Matter." Institute of Medicine. 2015. Emerging Viral Diseases: The One Health Connection: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/18975.
×

This page intentionally left blank.

Suggested Citation:"Front Matter." Institute of Medicine. 2015. Emerging Viral Diseases: The One Health Connection: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/18975.
×

BOARD ON GLOBAL HEALTH1

THOMAS C. QUINN (Chair), Associate Director for International Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Professor of Medicine, International Health, Epidemiology, and Molecular Biology and Immunology, Johns Hopkins University School of Medicine, Baltimore, Maryland

JO IVEY BOUFFORD (Ex-Officio), President, New York Academy of Medicine, New York, New York

GARY DARMSTADT, Director, Family Health Division, Global Health Program, The Bill & Melinda Gates Foundation, Seattle, Washington

JACOB A. GAYLE, Vice President, Community Affairs, Executive Director, Medtronic Foundation, Minneapolis, Minnesota

GLENDA E. GRAY, Executive Director, Perinatal HIV Research Unit, Chris Hani Baragwanath Hospital, University of the Witwatersrand, Diepkloof, South Africa

STEPHEN W. HARGARTEN, Professor and Chair, Emergency Medicine, Director, Medical College of Wisconsin, Milwaukee, Wisconsin

CLARION JOHNSON, Global Medical Director, Medicine and Occupational Medicine Department, ExxonMobil, Fairfax, Virginia

ALAN LESHNER, Chief Executive Officer, Executive Publisher, American Association for the Advancement of Science, Washington, DC

MYRON LEVINE, Simon and Bessie Grollman Distinguished Professor and Director Center for Vaccine Development, University of Maryland at Baltimore, Baltimore

GUY PALMER, Regents Professor of Pathology and Infectious Diseases, Director of the School for Global Animal Health, Washington State University, Pullman, Washington

ANNE PETERSEN, Research Professor, Center for Human Growth and Development, University of Michigan, Ann Arbor

DAVID VLAHOV, Dean and Endowed Professor of Nursing Education School of Nursing, University of California, San Francisco, Schools of Nursing and Medicine

IOM Staff

PATRICK KELLEY, Director

ANGELA CHRISTIAN,2 Program Associate

_______________

1 Institute of Medicine boards do not review or approve individual workshop summaries. The responsibility for the content of the workshop summary rests with the workshop rapporteurs and the institution.

2 Staff member until January 31, 2015.

Suggested Citation:"Front Matter." Institute of Medicine. 2015. Emerging Viral Diseases: The One Health Connection: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/18975.
×

This page intentionally left blank.

Suggested Citation:"Front Matter." Institute of Medicine. 2015. Emerging Viral Diseases: The One Health Connection: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/18975.
×

Reviewers

This workshop summary has been reviewed in draft form by individuals chosen for their diverse perspectives and technical expertise, in accordance with procedures approved by the National Research Council’s Report Review Committee. The purpose of this independent review is to provide candid and critical comments that will assist the institution in making its published workshop summary as sound as possible and to ensure that the workshop summary meets institutional standards for objectivity, evidence, and responsiveness to the study charge. The review comments and draft manuscript remain confidential to protect the integrity of the process. We wish to thank the following individuals for their review of this workshop summary:

CLAIRE FRASER, Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland

JAMES M. HUGHES, Global Infectious Diseases Program, Emory University, Atlanta, Georgia

STANLEY M. LEMON, University of North Carolina, Chapel Hill, North Carolina

MICHAEL WOROBEY, University of Arizona, Tucson, Arizona

Although the reviewers listed above have provided many constructive comments and suggestions, they did not see the final draft of the workshop summary before its release. The review of this workshop summary was overseen by Melvin Worth. Appointed by the Institute of Medicine, he was responsible for making certain that an independent examination of this workshop summary was carried out in accordance with institutional procedures and that all review comments were carefully considered. Responsibility for the final content of this workshop summary rests entirely with the rapporteurs and the institution.

Suggested Citation:"Front Matter." Institute of Medicine. 2015. Emerging Viral Diseases: The One Health Connection: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/18975.
×

This page intentionally left blank.

Page xiii Cite
Suggested Citation:"Front Matter." Institute of Medicine. 2015. Emerging Viral Diseases: The One Health Connection: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/18975.
×

Acknowledgments

The Forum on Emerging Infections was created by the Institute of Medicine (IOM) in 1996 in response to a request from the Centers for Disease Control and Prevention (CDC) and the National Institutes of Health (NIH). The purpose of the Forum is to provide structured opportunities for leaders from government, academia, and industry to regularly meet and examine issues of shared concern regarding research, prevention, detection, and management of emerging, reemerging, and novel infectious diseases in humans, plants, and animals. In pursuing this task, the Forum provides a venue to foster the exchange of information and ideas, identify areas in need of greater attention, clarify policy issues by enhancing knowledge and identifying points of agreement, and inform decision makers about science and policy issues. The Forum seeks to illuminate issues rather than resolve them. For this reason, it does not provide advice or recommendations on any specific policy initiative pending before any agency or organization. Its value derives instead from the diversity of its membership and from the contributions that individual members make throughout the activities of the Forum. In September 2003, the Forum changed its name to the Forum on Microbial Threats.

The Forum on Microbial Threats, and the IOM, wish to express their sincere appreciation to the individuals and organizations who contributed their valuable time to provide information and advice to the Forum. Their participation in the planning and execution of this workshop made it greater than the sum of its parts. A full list of presenters, and their biographical information, may be found in Appendix E.

Suggested Citation:"Front Matter." Institute of Medicine. 2015. Emerging Viral Diseases: The One Health Connection: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/18975.
×

The Forum gratefully acknowledges the contributions of the members of the planning committee1: Peter Daszak (EcoHealth Alliance), Jeffrey Duchin (Public Health–Seattle & King County), Carole Heilman (National Institute of Allergy and Infectious Diseases, NIH), James M. Hughes (Emory University), Rima Khabbaz (CDC), David Swayne (U.S. Department of Agriculture), and John Watson (Public Health England).

The Forum is also indebted to the IOM staff who tirelessly contributed throughout the planning and execution of the workshop and the production of this workshop summary report. On behalf of the Forum, we unreservedly acknowledge these efforts led by Dr. Eileen Choffnes, Scholar and Director of the Forum; Katherine McClure,2 Associate Program Officer; Rebekah Hutton,3 Research Associate; Priyanka Nalamada, Senior Program Assistant; and Joanna Roberts,4 Senior Program Assistant (Temp). Without the contributions and dedication of the staff to the work of the Forum in developing this workshop’s agenda and for their thoughtful and insightful approach and skill in planning for the workshop and in translating the workshop’s proceedings and discussion into this workshop summary report, this report would not have been possible. We would also like to thank the following IOM staff and consultants for their invaluable contributions to this activity: Laura Harbold DeStefano, Chelsea Frakes, Rosalind Gomes,5 Greta Gorman, Faye Hillman, Sarah Kelley, Alison Mack, and Julie Wiltshire.

Finally, the Forum wishes to recognize the sponsors that supported this activity. Financial support for this activity was provided by the U.S. Department of Health and Human Services: National Institutes of Health, National Institute of Allergy and Infectious Diseases, Centers for Disease Control and Prevention, and the Food and Drug Administration; U.S. Department of Defense: Armed Forces Health Surveillance Center, and U.S. Army Medical Research and Materiel Command; U.S. Department of Justice: Federal Bureau of Investigation; U.S. Department of Veterans Affairs; U.S. Department of Homeland Security; U.S. Agency for International Development; Uniformed Services University of the Health Sciences; Alfred P. Sloan Foundation; American Society for Microbiology; Infectious Diseases Society of America; Johnson & Johnson; Merck Company Foundation; and sanofi pasteur. The views presented in this workshop summary are those of the workshop participants and have been summarized by the rapporteurs. They do not necessarily reflect the views of the Forum on Microbial Threats, its sponsors, or the IOM.

_______________

1 Institute of Medicine planning committees are solely responsible for organizing the workshop, identifying topics, and choosing speakers. The responsibility for the published workshop summary rests solely with the workshop rapporteurs and the institution.

2 Staff member until December 31, 2014.

3 Staff member until November 14, 2015.

4 Staff member until March 31, 2014.

5 Staff member until January 9, 2015.

Suggested Citation:"Front Matter." Institute of Medicine. 2015. Emerging Viral Diseases: The One Health Connection: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/18975.
×
Suggested Citation:"Front Matter." Institute of Medicine. 2015. Emerging Viral Diseases: The One Health Connection: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/18975.
×

A7   Medusa’s Ugly Head Again: From SARS to MERS-CoV

Trish M. Perl, Allison McGeer, and Connie Savor Price

A8   The Relationship Between Eco-social System Changes, the Animal–Human Interface, and Viral Disease Emergence

Dirk U. Pfeiffer

A9   From Risk Analysis to Risk Governance—Adapting to an Ever More Complex Future

Dirk U. Pfeiffer

A10 A One Health Perspective on HPAI H5N1 in the Greater Mekong Sub-region

Dirk U. Pfeiffer, Martin J. Otte, David Roland-Holst, and David Zilberman

A11 Zoonosis Emergence Linked to Agricultural Intensification and Environmental Change

Bryony A. Jones, Delia Grace, Richard Kock, Silvia Alonso, Jonathan Rushton, Mohammed Y. Said, Declan McKeever, Florence Mutua, Jarrah Young, John McDermott, and Dirk U. Pfeiffer

A12 Global Trends in Emerging Viral Diseases of Wildlife Origin

Jonathan Sleeman and Hon Ip

A13 Role of Poultry in Spread of Novel H7N9 Influenza Virus in China

Mary J. Pantin-Jackwood, Patti J. Miller, Erica Spackman, David E. Swayne, Leonardo Susta, Mar Costa-Hurtado, and David L. Suarez

B Agenda

C Acronyms

D Glossary

E Speaker Biographies

Page xviii Cite
Suggested Citation:"Front Matter." Institute of Medicine. 2015. Emerging Viral Diseases: The One Health Connection: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/18975.
×

WO-23 Number of confirmed human H7N9 cases by week as of July 14, 2014

WO-24 Confirmed cases and deaths from avian influenza A (H7N9) from October 1, 2013, to the present

WO-25 The PVS pathway

WO-26 Live bird market (LBM) networks in Guangxi, Yunnan, and Hunan

WO-27 Stratifying risk

WO-28 Ongoing surveillance for H7N9: Laos and Myanmar

A1-1     Map of the initial investigation of bats as a reservoir for MERS-CoV in Bisha and Unaizah

A1-2     The top five camel-producing countries (1992–2013)

A1-3     Geographic range of 14 species in the bat genus Taphozous (green; data from IUCN) and overlap with approximate geographic range of dromedary camels (blue)

A5-1     H1N1 influenza pandemic

A6-1     Emergence of zoonoses

A6-2     The outcome of disease severity is influenced by the host–pathogen interaction

A6-3     The host immune response to an infection influences the disease outcome

A8-1     Perceived impact and likelihood of different risks based on a global risk perception survey, 2013–2014

A8-2     Temporal pattern of meat production intensity for different parts of the world between 1961and 2012

A8-3     Temporal pattern of value (in US$) of imports of pigs and pig products to China from various regions of the world between 1986 and 2011

A8-4     Eco-social system components influencing spread of HPAIV H5N1 in parts of Asia

A8-5     A systems perspective on disease emergence

A8-6     Components of the risk governance framework

A11-1   Pathogen flow at the wildlife–livestock–human interface

A12-1   Emerging diseases investigated by the U.S. Geological Survey

A12-2   Contact between humans and great apes is increasing due to ecotourism, and without preventive measures could result in cross-species pathogen exchange

Suggested Citation:"Front Matter." Institute of Medicine. 2015. Emerging Viral Diseases: The One Health Connection: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/18975.
×

A13-1   Comparison of oropharyngeal virus shedding after experimental challenge

A13-2   Histopathology and immunohistochemical staining for avian influenza virus antigen in tissues of quail intranasally infected with the A/Anhui/1/2013 (H7N9) virus 3 dpi

TABLES

WO-1   Natural Reservoir Hosts and Susceptible Hosts Involved in Transmission of a Selection of Emerging Zoonotic Diseases

WO-2   Coronaviruses That Emerged as a Result of Interspecies Transmission or Tissue Tropism Changes and Suggested Associated Genomic Modifications

WO-3   Emerging Porcine Coronaviruses—Target Tissues and Diseases

WO-4   Avian Influenza A (H7N9) Update: March 17, 2014

A3-1     Some Major Factors That Underlie Disease Emergence and Reemergence

A5-1     World Health Organization (WHO) Pandemic-Phase Descriptions and Main Actions According to Phase

A5-2     Recommendations of the WHO Review Committee on the Functioning of the 2005 International Health Regulations (IHR) in Relation to the 2009 H1N1 Influenza Pandemic

A6-1     Natural Reservoir Hosts and Susceptible Hosts Involved in Transmission of a Selection of Emerging Zoonotic Viral Diseases, Including Those Deemed to Have Pandemic Potential

A11-1   Conceptual Framework of Types of Wildlife–Livestock–Human Interfaces and Their Characteristics

A12-1   Highly Pathogenic Avian Influenza Outbreaks in Poultry and Wild Birds Since 1959

A12-2   Factors That Contributed to the Success of One Health Projects

A13-1   Susceptibility of Poultry to Influenza A (H7N9) Virus

A13-2   Transmission of Influenza A (H7N9) Virus in Quail, Pigeons, and Ducks

A13-3   Comparison of Common Sequence Polymorphisms in H7 HA1 and PB2 Proteins Between Parental Strain A/Anhui/1/2013 (H7N9) and Derivative Viruses Recovered from Birds Inoculated with A/Anhui/1/2013

Suggested Citation:"Front Matter." Institute of Medicine. 2015. Emerging Viral Diseases: The One Health Connection: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/18975.
×

This page intentionally left blank.

Suggested Citation:"Front Matter." Institute of Medicine. 2015. Emerging Viral Diseases: The One Health Connection: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/18975.
×
Page R1
Suggested Citation:"Front Matter." Institute of Medicine. 2015. Emerging Viral Diseases: The One Health Connection: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/18975.
×
Page R2
Suggested Citation:"Front Matter." Institute of Medicine. 2015. Emerging Viral Diseases: The One Health Connection: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/18975.
×
Page R3
Suggested Citation:"Front Matter." Institute of Medicine. 2015. Emerging Viral Diseases: The One Health Connection: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/18975.
×
Page R4
Suggested Citation:"Front Matter." Institute of Medicine. 2015. Emerging Viral Diseases: The One Health Connection: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/18975.
×
Page R5
Suggested Citation:"Front Matter." Institute of Medicine. 2015. Emerging Viral Diseases: The One Health Connection: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/18975.
×
Page R6
Suggested Citation:"Front Matter." Institute of Medicine. 2015. Emerging Viral Diseases: The One Health Connection: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/18975.
×
Page R7
Page viii Cite
Suggested Citation:"Front Matter." Institute of Medicine. 2015. Emerging Viral Diseases: The One Health Connection: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/18975.
×
Page R8
Suggested Citation:"Front Matter." Institute of Medicine. 2015. Emerging Viral Diseases: The One Health Connection: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/18975.
×
Page R9
Suggested Citation:"Front Matter." Institute of Medicine. 2015. Emerging Viral Diseases: The One Health Connection: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/18975.
×
Page R10
Suggested Citation:"Front Matter." Institute of Medicine. 2015. Emerging Viral Diseases: The One Health Connection: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/18975.
×
Page R11
Suggested Citation:"Front Matter." Institute of Medicine. 2015. Emerging Viral Diseases: The One Health Connection: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/18975.
×
Page R12
Page xiii Cite
Suggested Citation:"Front Matter." Institute of Medicine. 2015. Emerging Viral Diseases: The One Health Connection: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/18975.
×
Page R13
Suggested Citation:"Front Matter." Institute of Medicine. 2015. Emerging Viral Diseases: The One Health Connection: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/18975.
×
Page R14
Suggested Citation:"Front Matter." Institute of Medicine. 2015. Emerging Viral Diseases: The One Health Connection: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/18975.
×
Page R15
Suggested Citation:"Front Matter." Institute of Medicine. 2015. Emerging Viral Diseases: The One Health Connection: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/18975.
×
Page R16
Page xvii Cite
Suggested Citation:"Front Matter." Institute of Medicine. 2015. Emerging Viral Diseases: The One Health Connection: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/18975.
×
Page R17
Page xviii Cite
Suggested Citation:"Front Matter." Institute of Medicine. 2015. Emerging Viral Diseases: The One Health Connection: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/18975.
×
Page R18
Suggested Citation:"Front Matter." Institute of Medicine. 2015. Emerging Viral Diseases: The One Health Connection: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/18975.
×
Page R19
Suggested Citation:"Front Matter." Institute of Medicine. 2015. Emerging Viral Diseases: The One Health Connection: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/18975.
×
Page R20
Next: Workshop Overview »
Emerging Viral Diseases: The One Health Connection: Workshop Summary Get This Book
×
Buy Paperback | $75.00 Buy Ebook | $59.99
MyNAP members save 10% online.
Login or Register to save!
Download Free PDF

In the past half century, deadly disease outbreaks caused by novel viruses of animal origin - Nipah virus in Malaysia, Hendra virus in Australia, Hantavirus in the United States, Ebola virus in Africa, along with HIV (human immunodeficiency virus), several influenza subtypes, and the SARS (sudden acute respiratory syndrome) and MERS (Middle East respiratory syndrome) coronaviruses - have underscored the urgency of understanding factors influencing viral disease emergence and spread.

Emerging Viral Diseases is the summary of a public workshop hosted in March 2014 to examine factors driving the appearance, establishment, and spread of emerging, re-emerging and novel viral diseases; the global health and economic impacts of recently emerging and novel viral diseases in humans; and the scientific and policy approaches to improving domestic and international capacity to detect and respond to global outbreaks of infectious disease. This report is a record of the presentations and discussion of the event.

  1. ×

    Welcome to OpenBook!

    You're looking at OpenBook, NAP.edu's online reading room since 1999. Based on feedback from you, our users, we've made some improvements that make it easier than ever to read thousands of publications on our website.

    Do you want to take a quick tour of the OpenBook's features?

    No Thanks Take a Tour »
  2. ×

    Show this book's table of contents, where you can jump to any chapter by name.

    « Back Next »
  3. ×

    ...or use these buttons to go back to the previous chapter or skip to the next one.

    « Back Next »
  4. ×

    Jump up to the previous page or down to the next one. Also, you can type in a page number and press Enter to go directly to that page in the book.

    « Back Next »
  5. ×

    Switch between the Original Pages, where you can read the report as it appeared in print, and Text Pages for the web version, where you can highlight and search the text.

    « Back Next »
  6. ×

    To search the entire text of this book, type in your search term here and press Enter.

    « Back Next »
  7. ×

    Share a link to this book page on your preferred social network or via email.

    « Back Next »
  8. ×

    View our suggested citation for this chapter.

    « Back Next »
  9. ×

    Ready to take your reading offline? Click here to buy this book in print or download it as a free PDF, if available.

    « Back Next »
Stay Connected!