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Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2016. Review of NASA's Evidence Reports on Human Health Risks: 2015 Letter Report. Washington, DC: The National Academies Press. doi: 10.17226/21844.
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Review of NASA’s Evidence
Reports on Human Health Risks

2015 LETTER REPORT

Committee to Review NASA’s Evidence Reports
on Human Health Risks

Board on Health Sciences Policy

Carol E. H. Scott-Conner, Daniel R. Masys, and
Catharyn T. Liverman, Editors

Institute of Medicine

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THE NATIONAL ACADEMIES PRESS

Washington, DC

www.nap.edu

Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2016. Review of NASA's Evidence Reports on Human Health Risks: 2015 Letter Report. Washington, DC: The National Academies Press. doi: 10.17226/21844.
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THE NATIONAL ACADEMIES PRESS • 500 Fifth Street, NW • Washington, DC 20001

This project was supported by Contract NNH13CK19B, Task Order NNH13CK20D, between the National Academy of Sciences and the National Aeronautics and Space Administration. Any opinions, findings, conclusions, or recommendations expressed in this publication do not necessarily reflect the views of any organization or agency that provided support for the project.

International Standard Book Number-13: 978-0-309-38061-4
International Standard Book Number-10: 0-309-38061-8
Digital Object Identifier: 10.17226/21844

Additional copies of this report available for sale from the National Academies Press, 500 Fifth Street, NW, Keck 360, Washington, DC 20001; (800) 624-6242 or (202) 334-3313; http://www.nap.edu.

Copyright 2016 by the National Academy of Sciences. All rights reserved.

Printed in the United States of America

Suggested citation: National Academies of Sciences, Engineering, and Medicine. 2016. Review of NASA’s evidence reports on human health risks: 2015 letter report. Washington, DC: The National Academies Press. doi: 10.17226/21844.

Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2016. Review of NASA's Evidence Reports on Human Health Risks: 2015 Letter Report. Washington, DC: The National Academies Press. doi: 10.17226/21844.
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The National Academy of Sciences was established in 1863 by an Act of Congress, signed by President Lincoln, as a private, nongovernmental institution to advise the nation on issues related to science and technology. Members are elected by their peers for outstanding contributions to research. Dr. Ralph J. Cicerone is president.

The National Academy of Engineering was established in 1964 under the charter of the National Academy of Sciences to bring the practices of engineering to advising the nation. Members are elected by their peers for extraordinary contributions to engineering. Dr. C. D. Mote, Jr., is president.

The National Academy of Medicine (formerly the Institute of Medicine) was established in 1970 under the charter of the National Academy of Sciences to advise the nation on medical and health issues. Members are elected by their peers for distinguished contributions to medicine and health. Dr. Victor J. Dzau is president.

The three Academies work together as the National Academies of Sciences, Engineering, and Medicine to provide independent, objective analysis and advice to the nation and conduct other activities to solve complex problems and inform public policy decisions. The Academies also encourage education and research, recognize outstanding contributions to knowledge, and increase public understanding in matters of science, engineering, and medicine.

Learn more about the National Academies of Sciences, Engineering, and Medicine at www.national-academies.org.

Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2016. Review of NASA's Evidence Reports on Human Health Risks: 2015 Letter Report. Washington, DC: The National Academies Press. doi: 10.17226/21844.
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Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2016. Review of NASA's Evidence Reports on Human Health Risks: 2015 Letter Report. Washington, DC: The National Academies Press. doi: 10.17226/21844.
×

COMMITTEE TO REVIEW NASA’S EVIDENCE REPORTS
ON HUMAN HEALTH RISKS

CAROL E. H. SCOTT-CONNER (Chair), University of Iowa Carver College of Medicine, Iowa City

DANIEL R. MASYS (Vice Chair), University of Washington, Seattle

SUSAN A. BLOOMFIELD, Texas A&M University, College Station

C. PATRICK DUNNE, Dunne Solutions, Framingham, MA

BRAD HOLSCHUH, University of Minnesota, Twin Cities

MICHAEL J. JOYNER, Mayo Clinic, Rochester, MN

JAMES A. PAWELCZYK, Pennsylvania State University, University Park

K. P. SANDEEP, North Carolina State University, Raleigh

ROBERT L. SATCHER, JR., University of Texas, Houston

JACK STUSTER, Anacapa Sciences, Santa Barbara, CA

SCOTT TRAPPE, Ball State University, Muncie, IN

PETER D. WAGNER, University of California, San Diego

GAYLE E. WOLOSCHAK, Northwestern University Feinberg School of Medicine, Chicago, IL

LAURENCE R. YOUNG, Massachusetts Institute of Technology, Cambridge

IOM Staff

CATHARYN T. LIVERMAN, Study Director

CLAIRE F. GIAMMARIA, Research Associate

JUDITH L. ESTEP, Program Associate

SOPHIE YANG, Research Assistant

ANDREW M. POPE, Director, Board on Health Sciences Policy

Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2016. Review of NASA's Evidence Reports on Human Health Risks: 2015 Letter Report. Washington, DC: The National Academies Press. doi: 10.17226/21844.
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Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2016. Review of NASA's Evidence Reports on Human Health Risks: 2015 Letter Report. Washington, DC: The National Academies Press. doi: 10.17226/21844.
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Reviewers

This report has been reviewed in draft form by individuals chosen for their diverse perspectives and technical expertise. The purpose of this independent review is to provide candid and critical comments that will assist the institution in making its published report as sound as possible and to ensure that the report meets institutional standards for objectivity, evidence, and responsiveness to the study charge. The review comments and draft manuscript remain confidential to protect the integrity of the deliberative process. We wish to thank the following individuals for their review of this report:

ELDON W. ASKEW, University of Utah

DENNIS R. HELDMAN, The Ohio State University

SUSAN R. HOPKINS, University of California, San Diego

DAVID KIRSCH, Duke University Medical Center

JOANNE LUPTON, Texas A&M University

NEAL W. POLLOCK, Duke University Medical Center

FRANK A. SLOAN, Duke University

JOHN B. WEST, University of California, San Diego

Although reviewers listed above have provided many constructive comments and suggestions, they did not see the final draft of the report before its release. The review of this report was overseen by GLORIA LEON, University of Minnesota, who served as the coordinator. She was responsible for making certain that an independent examination of this report was carried out in accordance with institutional procedures and that all review comments were carefully considered. Responsibility for the final content of this report rests entirely with the authoring committee and the institution.

Page viii Cite
Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2016. Review of NASA's Evidence Reports on Human Health Risks: 2015 Letter Report. Washington, DC: The National Academies Press. doi: 10.17226/21844.
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Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2016. Review of NASA's Evidence Reports on Human Health Risks: 2015 Letter Report. Washington, DC: The National Academies Press. doi: 10.17226/21844.
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Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2016. Review of NASA's Evidence Reports on Human Health Risks: 2015 Letter Report. Washington, DC: The National Academies Press. doi: 10.17226/21844.
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Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2016. Review of NASA's Evidence Reports on Human Health Risks: 2015 Letter Report. Washington, DC: The National Academies Press. doi: 10.17226/21844.
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Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2016. Review of NASA's Evidence Reports on Human Health Risks: 2015 Letter Report. Washington, DC: The National Academies Press. doi: 10.17226/21844.
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Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2016. Review of NASA's Evidence Reports on Human Health Risks: 2015 Letter Report. Washington, DC: The National Academies Press. doi: 10.17226/21844.
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Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2016. Review of NASA's Evidence Reports on Human Health Risks: 2015 Letter Report. Washington, DC: The National Academies Press. doi: 10.17226/21844.
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Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2016. Review of NASA's Evidence Reports on Human Health Risks: 2015 Letter Report. Washington, DC: The National Academies Press. doi: 10.17226/21844.
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Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2016. Review of NASA's Evidence Reports on Human Health Risks: 2015 Letter Report. Washington, DC: The National Academies Press. doi: 10.17226/21844.
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Page viii Cite
Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2016. Review of NASA's Evidence Reports on Human Health Risks: 2015 Letter Report. Washington, DC: The National Academies Press. doi: 10.17226/21844.
×
Page R8
Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2016. Review of NASA's Evidence Reports on Human Health Risks: 2015 Letter Report. Washington, DC: The National Academies Press. doi: 10.17226/21844.
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Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2016. Review of NASA's Evidence Reports on Human Health Risks: 2015 Letter Report. Washington, DC: The National Academies Press. doi: 10.17226/21844.
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Review of NASA's Evidence Reports on Human Health Risks 2015 Letter Report is the third in a series of five reports from the Institute of Medicine that will independently review more than 30 evidence reports that the National Aeronautics and Space Administration has compiled on human health risks for long-duration and exploration space flights. This report builds on the 2008 IOM report Review of NASA's Human Research Program Evidence Books: A Letter Report, which provided an initial and brief review of the evidence reports.

This letter report reviews seven evidence reports and examines the quality of the evidence, analysis, and overall construction of each report; identifies existing gaps in report content; and provides suggestions for additional sources of expert input. The report analyzes each evidence report's overall quality, which included readability; internal consistency; the source and breadth of cited evidence; identification of existing knowledge and research gaps; authorship expertise; and, if applicable, response to recommendations from the 2008 IOM letter report.

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