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Acute Exposure Guideline Levels for Selected Airborne Chemicals: Volume 20 (2016)

Chapter: Appendix E Category Plots for Selected Chloroformates

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Suggested Citation:"Appendix E Category Plots for Selected Chloroformates." National Academies of Sciences, Engineering, and Medicine. 2016. Acute Exposure Guideline Levels for Selected Airborne Chemicals: Volume 20. Washington, DC: The National Academies Press. doi: 10.17226/23634.
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Appendix E

Category Plots for Selected Chloroformates

Image
FIGURE E-1 Category plot of toxicity data and AEGL values for methyl chloroformate.
Image
FIGURE E-2 Category plot of toxicity data and AEGL values for ethyl chloroformate.
Suggested Citation:"Appendix E Category Plots for Selected Chloroformates." National Academies of Sciences, Engineering, and Medicine. 2016. Acute Exposure Guideline Levels for Selected Airborne Chemicals: Volume 20. Washington, DC: The National Academies Press. doi: 10.17226/23634.
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Image
FIGURE E-3 Category plot of toxicity data and AEGL values for isopropyl chloroformate.
Image
FIGURE E-4 Category plot of toxicity data and AEGL values for n-propyl chloroformate.
Suggested Citation:"Appendix E Category Plots for Selected Chloroformates." National Academies of Sciences, Engineering, and Medicine. 2016. Acute Exposure Guideline Levels for Selected Airborne Chemicals: Volume 20. Washington, DC: The National Academies Press. doi: 10.17226/23634.
×
Image
FIGURE E-5 Category plot of toxicity data and AEGL values for allyl chloroformate.
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FIGURE E-6 Category plot of toxicity data and AEGL values for n-butyl, isobutyl, and sec-butyl chloroformate.
Suggested Citation:"Appendix E Category Plots for Selected Chloroformates." National Academies of Sciences, Engineering, and Medicine. 2016. Acute Exposure Guideline Levels for Selected Airborne Chemicals: Volume 20. Washington, DC: The National Academies Press. doi: 10.17226/23634.
×
Image
FIGURE E-7 Category plot of toxicity data and AEGL values for benzyl chloroformate.
Image
FIGURE E-8 Category plot of toxicity data and AEGL values for phenyl chloroformate.
Suggested Citation:"Appendix E Category Plots for Selected Chloroformates." National Academies of Sciences, Engineering, and Medicine. 2016. Acute Exposure Guideline Levels for Selected Airborne Chemicals: Volume 20. Washington, DC: The National Academies Press. doi: 10.17226/23634.
×
Image
FIGURE E-9 Category plot of toxicity data and AEGL values for 2-ethylhexyl chloroformate.
Image
FIGURE E-10 Category plot of toxicity data and AEGL values for ethyl chlorothioformate.
Suggested Citation:"Appendix E Category Plots for Selected Chloroformates." National Academies of Sciences, Engineering, and Medicine. 2016. Acute Exposure Guideline Levels for Selected Airborne Chemicals: Volume 20. Washington, DC: The National Academies Press. doi: 10.17226/23634.
×
Page 174
Suggested Citation:"Appendix E Category Plots for Selected Chloroformates." National Academies of Sciences, Engineering, and Medicine. 2016. Acute Exposure Guideline Levels for Selected Airborne Chemicals: Volume 20. Washington, DC: The National Academies Press. doi: 10.17226/23634.
×
Page 175
Suggested Citation:"Appendix E Category Plots for Selected Chloroformates." National Academies of Sciences, Engineering, and Medicine. 2016. Acute Exposure Guideline Levels for Selected Airborne Chemicals: Volume 20. Washington, DC: The National Academies Press. doi: 10.17226/23634.
×
Page 176
Suggested Citation:"Appendix E Category Plots for Selected Chloroformates." National Academies of Sciences, Engineering, and Medicine. 2016. Acute Exposure Guideline Levels for Selected Airborne Chemicals: Volume 20. Washington, DC: The National Academies Press. doi: 10.17226/23634.
×
Page 177
Suggested Citation:"Appendix E Category Plots for Selected Chloroformates." National Academies of Sciences, Engineering, and Medicine. 2016. Acute Exposure Guideline Levels for Selected Airborne Chemicals: Volume 20. Washington, DC: The National Academies Press. doi: 10.17226/23634.
×
Page 178
Acute Exposure Guideline Levels for Selected Airborne Chemicals: Volume 20 Get This Book
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Extremely hazardous substances can be released accidentally as a result of chemical spills, industrial explosions, fires, or accidents involving railroad cars and trucks transporting EHSs. Workers and residents in communities surrounding industrial facilities where these substances are manufactured, used, or stored and in communities along the nation's railways and highways are potentially at risk of being exposed to airborne EHSs during accidental releases or intentional releases by terrorists. Pursuant to the Superfund Amendments and Reauthorization Act of 1986, the U.S. Environmental Protection Agency (EPA) has identified approximately 400 EHSs on the basis of acute lethality data in rodents.

Acute Exposure Guideline Levels for Selected Airborne Chemicals, Volume 20 reviews and updates the technical support document on acute exposure guideline levels (AEGLs) for selected chloroformates. This update focuses on establishing AEGL-3 values for n-propyl chloroformate and isopropyl chloroformate, but will also consider whether any new data are available that would affect the proposed values for the other 10 chloroformates.

AEGLs represent threshold exposure limits (exposure levels below which adverse health effects are not likely to occur) for the general public and are applicable to emergency exposures ranging from 10 minutes (min) to 8 h. Three levels - AEGL-1, AEGL-2, and AEGL-3 - are developed for each of five exposure periods (10 min, 30 min, 1 h, 4 h, and 8 h) and are distinguished by varying degrees of severity of toxic effects. This report will inform planning, response, and prevention in the community, the workplace, transportation, the military, and the remediation of Superfund sites.

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