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Suggested Citation:"Appendix C: Glossary." National Academies of Sciences, Engineering, and Medicine. 2017. Implementation of Lung Cancer Screening: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/23680.
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Appendix C

Glossary

Coinsurance–the percentage of costs of a covered health care service that a patient is responsible for once the deductible has been paid (HealthCare.gov, 2016).

Decision aids–tools used to facilitate a shared decision-making conversation between a patient and clinician. These tools can help patients understand the clinical evidence and help them identify their preferences. Decision aids do not advise people to choose one option over another; instead, they help prepare patients to make informed decisions aligned with their values and preferences (Healthwise, 2016).

False negative–a person who has a disease but receives a negative test result.

False positive–a person who does not have a disease but receives a positive test result.

Incidental findings–clinical findings that are identified during diagnostic testing but are not related to the diagnostic test result (for lung cancer screening, this could include cardiac abnormalities, chronic obstructive pulmonary disease, aneurysms, or masses in other tissues).

Suggested Citation:"Appendix C: Glossary." National Academies of Sciences, Engineering, and Medicine. 2017. Implementation of Lung Cancer Screening: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/23680.
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Lead-time bias–an overestimation of a patient’s survival benefit among individuals without symptoms who are screened for cancer, compared to individuals with cancer that are detected by signs and symptoms when survival is measured from the time of diagnosis (American College of Physicians, 1999).

Length-time bias–an overestimation of a patient’s survival duration among individuals without symptoms who are screened for cancer due to the disproportionate number of slowly progressing cancers that will be detected (American College of Physicians, 1999).

Number needed to screen–the number of people who need to be screened to prevent one bad outcome.

Overdiagnosis–when a condition is diagnosed that would otherwise not go on to cause symptoms or death (Welch and Black, 2010, p. 605).

Pack-year–a way to measure the amount a person has smoked over a long period of time. It is calculated by multiplying the number of packs of cigarettes smoked per day by the number of years the person has smoked. For example, 1 pack-year is equal to smoking 1 pack per day for 1 year, or 2 packs per day for half a year, and so on (NCI, 2016).

Positive predictive value–the probability that individuals with a positive test result actually have the disease. True Positives/(True Positives + False Positives)

Screening–checking for disease when there are no symptoms. Because screening may find diseases at an early stage, there may be a better chance of curing the disease (NCI, 2016).

Sensitivity–the proportion of people with a disease who are correctly identified from all positive test results for the disease. True Positives/(True Positives + False Negatives)

Shared decision making–is a collaborative process that allows patients and their providers to make health care decisions together. It takes into account the best clinical evidence available, as well as the patient’s values and preferences. Shared decision making is not a goal. The goal is better health decisions to achieve outcomes that matter most to the patient. And shared

Suggested Citation:"Appendix C: Glossary." National Academies of Sciences, Engineering, and Medicine. 2017. Implementation of Lung Cancer Screening: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/23680.
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decision making is a way to reach that goal. A proven process to incorporate the patient’s voice in health care decisions, shared decision making is the pinnacle of patient-centered care (Healthwise, 2016).

Specificity–the proportion of people who are correctly identified as not having a disease from all negative test results for the disease. True Negatives/ (True Negatives + False Positives)

REFERENCES

American College of Physicians. 1999. Finding and redefining disease. http://ecp.acponline.org/marapr99/primer.htm (accessed September 30, 2016).

HealthCare.gov. 2016. Coinsurance. https://www.healthcare.gov/glossary/co-insurance (accessed September 30, 2016).

Healthwise. 2016. Why shared decision making? http://www.informedmedicaldecisions.org/shareddecisionmaking.aspx (accessed August 29, 2016).

IOM and NRC (Institute of Medicine and National Research Council). 2001. Mammography and beyond: Developing technologies for the early detection of breast cancer. Washington, DC: National Academy Press.

NCI (National Cancer Institute). 2016. NCI dictionary of cancer terms. https://www.cancer.gov/publications/dictionaries/cancer-terms (accessed September 19, 2016).

Welch, H. G., and W. C. Black. 2010. Overdiagnosis in cancer. Journal of the National Cancer Institute 102(9):605-613.

Suggested Citation:"Appendix C: Glossary." National Academies of Sciences, Engineering, and Medicine. 2017. Implementation of Lung Cancer Screening: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/23680.
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Suggested Citation:"Appendix C: Glossary." National Academies of Sciences, Engineering, and Medicine. 2017. Implementation of Lung Cancer Screening: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/23680.
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Page 103
Suggested Citation:"Appendix C: Glossary." National Academies of Sciences, Engineering, and Medicine. 2017. Implementation of Lung Cancer Screening: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/23680.
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Page 104
Suggested Citation:"Appendix C: Glossary." National Academies of Sciences, Engineering, and Medicine. 2017. Implementation of Lung Cancer Screening: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/23680.
×
Page 105
Suggested Citation:"Appendix C: Glossary." National Academies of Sciences, Engineering, and Medicine. 2017. Implementation of Lung Cancer Screening: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/23680.
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The public health burden from lung cancer is substantial: it is the second most commonly diagnosed cancer and the leading cause of cancer-related deaths in the United States. Given the individual and population health burden of lung cancer, especially when it is diagnosed at later stages, there has been a push to develop and implement screening strategies for early detection. However, many factors need to be considered for broad implementation of lung cancer screening in clinical practice. Effective implementation will entail understanding the balance of potential benefits and harms of lung cancer screening, defining and reaching eligible populations, addressing health disparities, and many more considerations.

In recognition of the substantial challenges to developing effective lung cancer screening programs in clinical practice, the National Academies of Sciences, Engineering, and Medicine held a workshop in June 2016. At the workshop, experts described the current evidence base for lung cancer screening, the current challenges of implementation, and opportunities to overcome them. Workshop participants also explored capacity and access issues; best practices for screening programs; assessment of patient outcomes, quality, and value in lung cancer screening; and research needs that could improve implementation efforts. This publication summarizes the presentations and discussions from the workshop.

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