B
PUBLIC MEETING AGENDAS
Committee on Preventing Dementia and Cognitive Impairment
First Committee Meeting
Open Sessions: December 15-16, 2015
National Academy of Sciences Building
2101 Constitution Avenue, NW | Washington, DC 20418
DAY ONE—TUESDAY, DECEMBER 15
11:00 a.m. | Welcome and Introductions |
Alan Leshner, Chair, Committee on Preventing Dementia and Cognitive Impairment CEO Emeritus, American Association for the Advancement of Science |
|
11:05 a.m. |
Delivery of Study Charge and Q&A/Discussion with Committee Objectives:
|
Delivery of Charge
Richard Hodes, Director, NIA Overview of AHRQ ProcessKim Wittenberg, Health Scientist Administrator, AHRQ Overview of EPC progress to date and areas for committee inputRobert Kane, Director, Minnesota Evidence-based Practice Center |
|
Discussion | |
12:30 p.m. | Lunch |
1:15 p.m. | Follow-Up Q&A/Discussion to Clarify Remaining Questions by the Committee on the Study Charge |
Alan I. Leshner, Chair, Committee on Preventing Dementia and Cognitive Impairment CEO Emeritus, American Association for the Advancement of Science |
|
Richard Hodes, Director, NIA Kim Wittenberg, Health Scientist Administrator, AHRQ Robert Kane, Mary Butler, and Howard Fink, Minnesota Evidence-based Practice Center |
|
2:30 p.m. | Public Comment Period |
3:15 p.m. | Adjourn Open Session |
DAY TWO—WEDNESDAY, DECEMBER 16
10:15 a.m. | Follow-Up Discussion/Q&A Regarding the Systematic Review Objective: Discuss any remaining issues, questions, or points of clarification for the systematic review. |
Alan I. Leshner, Chair, Committee on Preventing Dementia and Cognitive Impairment CEO Emeritus, American Association for the Advancement of Science |
Marie A. Bernard, Deputy Director, NIA Kim Wittenberg, Health Scientist Administrator, AHRQ Robert Kane, Mary Butler, and Howard Fink, Minnesota Evidence-based Practice Center |
|
11:15 a.m. | Adjourn Open Session |
Preventing Dementia and Cognitive Impairment: A Workshop
Open Session: October 25, 2016
National Academy of Sciences Building
2101 Constitution Avenue, NW | Washington, DC 20418
Background: Many organizations and individuals worldwide are interested in the state of the science on preventing Alzheimer’s disease and related dementias, mild cognitive impairment (MCI), and age-related cognitive decline (ARCD). To develop a better understanding of current scientific evidence, implications for public health messaging, and future research needs, the National Institute on Aging (NIA) asked the National Academies of Sciences, Engineering, and Medicine (the National Academies) to convene an expert committee to make recommendations that inform public health strategies and messaging on preventive interventions and recommendations for future research. To aid the committee in its work, NIA has asked the Agency for Healthcare Research and Quality (AHRQ) to commission and oversee a systematic review—conducted by the Minnesota Evidence-based Practice Center (EPC)—of the evidence on interventions associated with preventing, slowing, or delaying the onset of clinical Alzheimer’s-type dementia and MCI, and delaying or slowing ARCD. Other dementias such as frontotemporal dementia, Lewy body dementia, and dementias with a clear etiology, e.g., incident stroke, AIDS, traumatic brain injury will be excluded from the analysis. Interventions targeting stroke risk factors are a priority in this study. To help inform the National Academies committee’s recommendations, this public workshop will bring together key stakeholders to provide input to the committee on the draft AHRQ report. The National Academies committee’s report is expected to be released in June 2017.
Workshop Objectives:
- Collect reactions to the draft EPC systematic review on preventive interventions that might reduce the risk of developing clinical Alzheimer’s-type dementia and mild cognitive impairment, and slow or delay age-related cognitive impairment/decline.
- Explore the current state of evidence on preventive interventions and discuss areas where public health messaging might be warranted.
- Discuss promising, emerging data on interventions that did not meet the evidentiary standard of the systematic review, and identify gaps and areas for future research.
8:00 a.m. | Welcome and Overview of Workshop Alan Leshner, CEO Emeritus, American Association for the Advancement of Science, Committee Chair Story Landis, Director Emeritus, National Institute of Neurological Disorders and Stroke, Committee Vice-Chair |
8:05 a.m. | Background and Overview of the Committee’s Charge Marie A. Bernard, Deputy Director, National Institute on Aging |
8:15 a.m. | Overview of the Draft EPC Systematic Review Robert Kane, Director, Minnesota Evidence-based Practice Center |
9:00 a.m. | Discussion with Committee Members Additional Respondents: Mary Butler and Howard Fink, Minnesota Evidence-based Practice Center |
10:00 a.m. | BREAK |
10:15 a.m. |
Making Decisions About Areas for Public Health Messaging
|
Brian Southwell, Program Director, Science in the Public Sphere, Center for Communication Science, RTI International | |
10:45 a.m. | Discussion with Committee Members |
SESSION I: PUBLIC HEALTH MESSAGING AND FUTURE RESEARCH—PERSPECTIVES FROM ACADEMIA
Session Objectives:
- Reflect on the current state of evidence on preventive interventions (not risk factors) and where public health messaging might be warranted.
- Discuss promising, emerging data on interventions that did not meet the evidentiary standard of the systematic review.
- Identify gaps and priorities for future research.
11:00 a.m. | Session Overview Ronald Petersen, Director of the Alzheimer’s Disease Research Center and Mayo Clinic Study of Aging, Mayo Clinic |
11:05 a.m. | Public Health Trends: Understanding the Impact of Individual and Societal Factors on Delaying or Preventing the Risk of Dementia and Cognitive Impairment Walter Rocca, Professor of Neurology and Epidemiology, Mayo Clinic |
Panel I: Perspectives from Academia | |
11:20 a.m. | Interventions on Co-Existing Conditions (e.g., blood pressure control, depressive symptoms, diabetes prevention and control, and obesity and weight loss) |
Vascular Factors, Diabetes, and Obesity Rebecca Gottesman, Associate Professor of Neurology, Johns Hopkins University Jeff Williamson, Interim Chair of Internal Medicine; Program Director of the Sticht Center on Aging; Professor of Gerontology and Geriatric Medicine, Neurology, Epidemiology & Prevention, and Translational Science Institute, Wake Forest Baptist Health |
|
Multimodal Interventions Edo Richard, Neurologist, University of Amsterdam, Academic Medical Center; Radboud University Medical Center |
11:50 a.m. | Discussion with Committee Members Including questions on interventions using drugs and supplements (e.g., aspirin/nonsteroidal anti-inflammatory drugs, drugs for memory, hormone therapies, nutraceuticals, and vitamins) |
12:30 p.m. | LUNCH |
1:30 p.m. | Interventions on Lifestyle and Social Support Factors (e.g., cognitive stimulation and training, diet, physical activity, sleep quality and disorder, and substance use) |
Diet and Physical Activity Joe Verghese, Professor of Neurology and Medicine, Director of the Division of Cognition and Motor Aging, Director of the Jack and Pearl Resnick Gerontology Center, Albert Einstein College of Medicine |
|
Cognitive Training and Computer-Based Brain Games Sherry Willis, Research Professor, Department of Psychiatry and Behavioral Sciences, University of Washington |
|
Sleep Quality and Disorders Susan McCurry, Research Professor and Vice Chair of Research of Psychosocial and Community Health, University of Washington |
|
2:15 p.m. | Methodological Considerations Pertaining to the Prevention of Dementia (e.g., life course perspective, timing of interventions, and characteristics of people living with dementia) Mary Sano, Professor of Psychiatry and Director of the Alzheimer’s Disease Research Center, Mount Sinai School of Medicine |
2:30 p.m. | Individual Characteristics: Interventions Conducted in Minority Populations Julene Johnson, Professor of Cognitive Neuroscience; Professor and Associate Director at the University of California, San Francisco, Institute for Health & Aging |
2:45 p.m. | Discussion with Committee Members |
3:30 p.m. | BREAK |
SESSION II: PERSPECTIVES FROM PEOPLE LIVING WITH DEMENTIA, ADVOCACY ORGANIZATIONS, AND PROFESSIONAL SOCIETIES
Session Objectives:
- Comment on which preventive interventions and outcomes are of most interest to people living with dementia and their caregivers.
- Collect input from advocacy organizations and professional societies’ on the EPC draft systematic review, the current state of evidence on preventive interventions and where public health messaging might be warranted, and areas for future research.
3:45 p.m. | Session Overview Marilyn Albert, Professor of Neurology and Director of the Division of Cognitive Neuroscience, Johns Hopkins University School of Medicine |
3:50 p.m. | Panel II: Comments from Alzheimer’s Disease/Dementia Advocates Michael Ellenbogen, Alzheimer’s Disease/Dementia Advocate (video recording) Brian LeBlanc, National Public Speaker/Alzheimer’s Advocate |
4:10 p.m. | Panel III: Perspectives from Advocacy Organizations Matthew Baumgart, Senior Director of Public Policy, Alzheimer’s Association Sarah Lenz Lock, Senior Vice President-Policy in Policy Strategy & International Affairs, AARP Stacy Pagos Haller, President and Chief Executive Officer, BrightFocus Foundation |
4:25 p.m. | Discussion with Committee Members |
4:40 p.m. | Panel IV: Perspectives from Professional Societies James Appleby, Chief Executive Officer and Executive Director, The Gerontological Society of America Mary Ann Forciea, Clinical Professor of Geriatric Medicine, University of Pennsylvania Perelman School of Medicine; American College of Physicians Lisa Shulman, Eugenia Brin Professor of Parkinson’s Disease and Movement Disorders, Director of the University of Maryland Movement Disorders Center, University of Maryland; Treasurer, American Academy of Neurology Regina Davis Moss, Associate Executive Director of Public Health Policy and Practice, American Public Health Association |
5:00 p.m. | Discussion with Committee Members |
5:15 p.m. | Public Comment Period |
5:25 p.m. | Closing Remarks Alan Leshner, Committee Chair Story Landis, Committee Vice-Chair |
5:30 p.m. | Public Session Adjourns |
Third Committee Meeting
Open Session: January 31, 2017
Meeting Objective:
- Discuss significant changes from the draft to the final AHRQ systematic review, which forms the predominant basis for the work of the National Academies’ Committee on Preventing Dementia and Cognitive Impairment.
9:00-9:05 a.m. | Welcome Alan Leshner, CEO Emeritus, American Association for the Advancement of Science, Committee Chair |
Brief Remarks Richard Hodes, Director, NIA Marie A. Bernard, Deputy Director, NIA |
|
9:05-9:25 a.m. | Overview of Changes from the Draft to the Final AHRQ Systematic Review Robert Kane, Director, Minnesota Evidence-based Practice Center |
9:25-10:00 a.m. | Discussion with Committee Members Additional Respondents: Mary Butler and Howard Fink, Minnesota Evidence-based Practice Center |
10:00 a.m. | Adjourn open session |