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Suggested Citation:"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2018. Strategies for Effective Improvements to the BioWatch System: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25014.
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Appendix B

Workshop Agenda

Strategies for Effective Biological Detection Systems: A Workshop
September 18-19, 2017

AGENDA

Location: National Academy of Sciences Building
Fred Kavli Auditorium
2101 Constitution Avenue, NW, Washington, DC 20418

WORKSHOP OBJECTIVES

To explore alternative and effective biodetection systems for aerosolized agents that meet technical and operational requirements for the Department of Homeland Security’s BioWatch program.

To focus on the integration of improvements and new technologies into the existing biological detection architecture.

To focus on systems or strategies that could:

  • be deployed by 2027,
  • enable indoor surveillance, and
  • benefit day-to-day environmental surveillance by the public health and medical communities.

DAY ONE—Monday, September 18, 2017

8:30 am SESSION I: INTRODUCTION AND BIOWATCH OVERVIEW
Welcome, Introductions, and Workshop Objectives

Adel A. F. Mahmoud, Planning Committee Chair
Professor in Molecular Biology and Public Policy, Woodrow Wilson School of Public and International Affairs and Department of Molecular Biology
Princeton University
8:40 am Welcome from BioWatch Program
Michael V. Walter, BioWatch Program Manager, Department of Homeland Security
Suggested Citation:"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2018. Strategies for Effective Improvements to the BioWatch System: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25014.
×
8:55 am Panel Discussion 1: Scope of the Workshop

Moderator: Adel A.F. Mahmoud, Planning Committee Chair
John D. Clements, Professor and Chair of Microbiology & Immunology, Tulane University School of Medicine
Bruce Budowle, Director, Center for Human Identification, University of North Texas Health Science Center
Tom Slezak, Distinguished Member of the Technical Staff, Lawrence Livermore National Lab
Colin Stimmler, Senior Director for the Bureau of Agency Preparedness & Response (BAPR), New York City Department of Health and Mental Hygiene (DOHMH)
David W. Cullin, Vice President Research, Development and Programs, FLIR Systems
Grace Kubin, Director Laboratory Services Section, Texas Department of State Health Services
Norman Kahn, President, Counter-Bio LLC
Fred M. Rosa, Jr., Senior Advisor for Homeland Security, Johns Hopkins Applied Physics Laboratory

9:40 am Full Workshop Question and Answer (Q&A)
10:00 am BioWatch Overview: Summary of Invited Paper
Paul Biedrzycki, Director of Disease Control and Environmental Health, Milwaukee City Health Department (retired)
10:30 am BREAK
10:45 am SESSION II: ASSESSMENT OF CURRENT PERFORMANCE
Assessment of Current Performance: Summaries of Invited Papers

Current Quality Assurance (QA) Approach
Molly Isbell, Director of Quality Assurance (QA) and Data Science, Signature Science
Use of Dispersion Modeling Tools in Optimizing Biological Detection Architectures
David Brown, Research Scientist, Argonne National Laboratory (ANL)
11:25 am Panel Discussion 2: How Improvements Might Impact Current Operations and the QA Process

Moderator:  John Clements, Planning Committee Member
Molly Isbell, Signature Science
David Brown, ANL
Jennifer Rakeman-Cagno, Assistant Commissioner, New York City Department of Health and Mental Hygiene

Full Workshop Q&A
12:40 pm LUNCH
Suggested Citation:"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2018. Strategies for Effective Improvements to the BioWatch System: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25014.
×
1:40 pm SESSION III: DEVELOPING EFFECTIVE BIOLOGICAL DETECTION SYSTEMS
Technology-Focused Outlook for Future Biological Detection Systems: Summary of Invited Paper

Authors: Duncan MacCannell, Chief Science Officer, Office of Advanced Molecular Detection, Centers for Disease Control and Prevention (CDC), and Toby Merlin, Director of the Division of Preparedness and Emerging Infections, CDC
Presenter: Toby Merlin, CDC
2:10 pm PANEL DISCUSSION 3A: Enhancements to Existing Systems

Moderator: Bruce Budowle, Planning Committee Member
Capture and Extraction
Dana Kadavy, Director of Biological Sciences, Signature Science Improvements to PCR
Henry Erlich, Senior Scientist, Children’s Hospital Oakland Research Institute (CHORI)
Enhancing Informatics, Data Flow, and Connectivity
C. Titus Brown, Associate Professor, University of California, Davis

3:25 pm BREAK
3:40 pm PANEL DISCUSSION 3B: Novel Technologies to Expand Capabilities

Moderator: Tom Slezak, Planning Committee Member
Mass spectrometry
Wayne Bryden, President, Zeteo Tech
Point-of-need multiplex PCR
Lyle L. Probst, CEO, Excite PCR Corporation
Rapid targeted Next-Generation Sequencing (NGS)
Sam Reed, President, DNA Electronics

4:55 pm RECAP AND REVIEW
Adel A. F. Mahmoud, Planning Committee Chair
5:25 pm ADJOURN DAY 1

DAY TWO—Tuesday, September 19, 2017

8:30 am WELCOME AND RECAP OF DAY ONE
Adel A. F. Mahmoud, Planning Committee Chair
8:45 am SESSION III: DEVELOPING EFFECTIVE BIOLOGICAL DETECTION SYSTEMS (CONT.)
PANEL DISCUSSION 3C: Indoor Survellience Requirements

Moderator: Colin Stimmler, Planning Committee Member Modeling
James C. Liljegren, Research Scientist, ANL
Transit security

Suggested Citation:"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2018. Strategies for Effective Improvements to the BioWatch System: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25014.
×
Chuck Burrus, Deputy Chief, Department of Security, MTA [Metropolitan Transportation Authority]/New York City Transit 
Operations
Suzet McKinney, Executive Director, Illinois Medical District Commission
Full Workshop Q&A
10:00 am BREAK
10:15 am SESSION IV: COMPATIBILITY OF BIOWATCH IMPROVEMENTS WITHIN EXISTING BIOLOGICAL DETECTION ARCHITECTURE
BioWatch Improvements Within Existing Biological Detection Architecture: Summary of Invited Paper

George Dizikes, Director, Knoxville Regional Laboratory, Tennessee Department of Health
10:45 am PANEL DISCUSSION 4A: Perspectives from the Response Network on Improvements and Current Gaps

Moderator: David Cullin, Planning Committee Member
David Silcott, President, S3I
Maureen (Moe) Sullivan, Emergency Preparedness and Response
Laboratory Supervisor, Minnesota Public Health Laboratory Department of Health
Mark Buttner, Associate Laboratory Director, Nevada State Public
Health Laboratory, UNLV Branch
Toby Merlin, CDC

Full Workshop Q&A
12:00 pm LUNCH
1:00 pm PANEL DISCUSSION 4B: Operational Considerations of Novel Technologies and New Modalities

Moderator: Grace Kubin, Planning Committee Member
Dee Pettit, Assistant Director, North Carolina State Laboratory of Public Health
M. Allen Northrup, Chief Executive Officer (CEO), MIODx
Toby Merlin, CDC

Full Workshop Q&A
2:15 pm BREAK
Suggested Citation:"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2018. Strategies for Effective Improvements to the BioWatch System: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25014.
×
2:30 pm FINAL SESSION: OVERVIEW OF THE WORKSHOP
Scoping of the Final Session

Adel A. F. Mahmoud, Planning Committee Chair
Major Topics of the Workshop Within the Context of United States Biodefense Efforts
Asha M. George, Co-Director, Blue Ribbon Study Panel on Biodefense
3:05 pm FINAL PANEL DISCUSSION

Moderator: Adel A. F. Mahmoud, Planning Committee Chair
Panel: Planning Committee Members
John D. Clements
Bruce Budowle
Tom Slezak
Colin Stimmler
Grace Kubin
Norman Kahn
Fred M. Rosa, Jr.

3:55 pm Full Workshop Q&A and Comments

Moderator: Adel A. F. Mahmoud, Planning Committee Chair

4:45 pm WRAP UP
Adel A. F. Mahmoud, Planning Committee Chair
5:00 pm ADJOURN
Suggested Citation:"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2018. Strategies for Effective Improvements to the BioWatch System: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25014.
×
Page 91
Suggested Citation:"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2018. Strategies for Effective Improvements to the BioWatch System: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25014.
×
Page 92
Suggested Citation:"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2018. Strategies for Effective Improvements to the BioWatch System: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25014.
×
Page 93
Suggested Citation:"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2018. Strategies for Effective Improvements to the BioWatch System: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25014.
×
Page 94
Suggested Citation:"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2018. Strategies for Effective Improvements to the BioWatch System: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25014.
×
Page 95
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BioWatch is the Department of Homeland Security’s (DHS’s) system for detecting an aerosolized biological attack using collectors that are positioned strategically across the country to continuously monitor the air for biological threats. As currently deployed, BioWatch collectors draw air through filters that field technicians collect daily and transport to laboratories, where professional technicians analyze the material collected on the filter for evidence of biological threats.

As part of the BioWatch program’s efforts to enhance its effectiveness and capabilities, particularly with regard to detecting biological threats in challenging indoor environments, DHS requested the National Academies of Sciences, Engineering, and Medicine hold a workshop to explore alternative and effective biodetection systems for aerosolized biological agents that would meet BioWatch’s technical and operational requirements, integrate into the existing system architecture and public health infrastructure, and be deployable by 2027. This publication summarizes the presentations and discussions from the workshop.

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